Published in Health and Medicine Week, July 11th, 2005
Study 1: Researchers at the U.S. Food and Drug Administration have proposed a new antiviral pathway that mediates hepatitis C virus (HCV) replicon interferon sensitivity through ADAR1 (double-stranded RNA).
"While many clinical hepatitis C virus (HCV) infections are resistant to alpha interferon (IFN-alpha) therapy, subgenomic in vitro self-replicating HCV RNAs (HCV replicons) are characterized by marked IFN-alpha sensitivity. IFN-alpha treatment of replicon-containing cells results in a rapid loss of viral RNA via translation inhibition through...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Health and Medicine Week
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.