Embryology
Growth factors increase liver-specific gene expressions mouse midfetal liver
Published in Health and Medicine Week, July 18th, 2005
"Growth factors (GF) are thought to affect the growth and differentiation of hepatocytes during liver development. However, in the midfetal liver, little is known concerning the role of GF," scientists in Japan report.
"The DNA synthesis of fetal liver epithelial cells (FLEC) in monolayer culture and the liver-specific gene expressions of FLEC in 3-D culture were examined in medium supplemented with various GF. DNA synthesis of FLEC was higher than that of adult hepatocytes without GF and was increased by hepatocyte growth factor (HGF); heparin-binding epidermal...
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