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Allergy and Immunology
Lymphatic tissue does not support hepatitis B replication in carriers
July 25th, 2005
Lymphatic tissue does not support hepatitis B replication in carriers. According to recent research published in the Journal of Hepatology, "hepatitis B virus (HBV) infection in extrahepatic tissues is controversial. To clarify whether episomal HBV can infect nonhepatic tissues, we investigated the molecular forms of HBV in the lymphatic cells of inactive HBV carriers who lacked viremia, thus avoiding contamination with HBV genomes originating from the viral particles present in the serum." "We assessed HBV genome, replicative forms, and viral integrants in the liver, serum, peripheral blood mononuclear cells (PBMC), and lymph nodes of 21...
Source: Health & Medicine Week (2005-07-25)
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