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Allergy and Immunology
Patients coinfected with hepatitis C and HIV mount a full response to F protein
July 25th, 2005
Patients coinfected with hepatitis C and HIV mount a full response to F protein. According to recent research from Canada, "hepatitis C virus (HCV) F protein is encoded in an alternate reading frame overlapping the core protein region. Its precise sequence, biological function and mode of expression are currently unclear." "This study was conducted to examine the prevalence and characteristics of host humoral and cell-mediated immune responses directed against F protein in patients co-infected with HCV and HIV-1. Mutations were introduced to allow the expression of HCV-1a F protein in the absence of core," wrote M. Troesch and colleagues, Hopital...
Source: Health & Medicine Week (2005-07-25)
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