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Anesthesia
Clonidine is a safe and effective alternative to epinephrine in oral surgery
July 25th, 2005
Clonidine is a safe and effective alternative to epinephrine in oral surgery. According to recent research from Serbia Monteneg, "The admixture of clonidine or epinephrine to lidocaine for inferior alveolar nerve block was studied with regard to onset, duration, intensity of anesthesia, postoperative analgesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), ST segment depression 1 mm and cardiac arrhythmias. Forty healthy patients (ASA I) received 2 ml 2% lidocaine with clonidine (15 mg/ml; n=20) or epinephrine (12.5 mg/ml; n=20) in a double-blind fashion for lower third molar surgery." ...
Source: Health & Medicine Week (2005-07-25)
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