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Anesthesia
I.V. anesthetics restore cerebral autoregulation; volatile anesthetics do not
July 25th, 2005
Propofol, an intravenous anesthetic, restores cerebral autoregulation by reducing blood velocity while isoflurane, a volatile anesthetic, does not. According to recent research from Italy, "Volatile anesthetics are thought to impair cerebral autoregulation more than i.v. anesthetics. However, few comparative studies have been carried out in humans." G. Decosmo and associates reported, "The aim of our study was to evaluate the differences in cerebral hemodynamic changes after introduction of isoflurane (a volatile anesthetic) and propofol (an i.v. anesthetic). Eighteen consecutive patients submitted to laparoscopic cholecystectomy were selected. After...
Source: Health & Medicine Week (2005-07-25)
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