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Acetylcholine Receptors
Drosophila acetylcholine receptor studied, binding of bungarotoxin revealed
July 25th, 2005
According to a recent study from the United States, the Drosophila acetylcholine receptor subunit D alpha 5 is part of an alpha-bungarotoxin binding acetylcholine receptor. "The central nervous system of Drosophila melanogaster contains an alpha-bungarotoxin-binding protein with the properties expected of a nicotinic acetylcholine receptor. This protein was purified 5800-fold from membranes prepared from Drosophila heads," wrote P.P. Wu and colleagues, City University of New York, Hunter College. "The protein was solubilized with 1% Triton X-100 and 0.5 M sodium chloride and then purified using an alpha-cobratoxin column followed by a lentil...
Source: Health & Medicine Week (2005-07-25)
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