AIDS-Related Emphysema
AIDS-related emphysema partly due to direct alveolar macrophage HIV-1 infection
Published in Health and Medicine Week, August 15th, 2005
According to a study from the United States, "HIV-seropositive individuals are at an increased risk for an accelerated form of emphysema. The purpose of this study was to determine the distribution of HIV-1 RNA in lung tissues and correlate this with the histologic findings and expression of matrix metalloproteases (MMPs)."
"Reverse transcriptase (RT) in situ PCR analysis was performed on 11 AIDS lung autopsy specimens which showed varying degrees of emphysematous changes. In each lung," said the authors, "HIV-1 RNA was detected. In areas of histologically normal...
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