HIV/AIDS Pediatrics
HIV-infected children have poorer qualitative antibody response to PnCV
Published in Health and Medicine Week, August 15th, 2005
Researchers in South Africa conducted a study "to determine the quantitative and qualitative antibody responses to a pneumococcal conjugate vaccine (PnCV) in human immunodeficiency virus (HIV)-exposed infected and uninfected children. Children were randomized to receive either a PnCV or placebo at 6, 10 and 14 weeks of age.
"PnCV serotype-specific antibody concentrations were measured by a standard enzyme immunoassay (EIA) and a 22F modified EIA (22F EIA) on single serum samples drawn at 21-42 days postdose 3. Functional activities of the...
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