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Addiction Medicine

Vaccine pharmacotherapy for treatment of cocaine dependence determined

Published in Health and Medicine Week, September 19th, 2005

Scientists report vaccine pharmacotherapy for the treatment of cocaine dependence in a recent issue of Biological Psychiatry.

According to a study from the United States, "Cocaine abuse has no established pharmacotherapy, but active immunotherapy with a cocaine vaccine shows promise as a therapeutic intervention. An open label, 14 week, dose-escalation study evaluated the safety, immunogenicity, and clinical efficacy of a novel human cocaine vaccine (TA-CD) in eighteen cocaine-dependent subjects."

"Ten subjects (400 mcg total dose group) received four-100 mcg injections over the course of 8 weeks," said Bridget A. Martell and colleagues at...

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