Neurology
Researchers' data advance neurology research
Published in Health and Medicine Week, October 10th, 2005
Study 1: A study from Japan has reported on the transcriptional regulation of neuronal genes and its effect on neural functions.
"Forkhead box transcription factor, class O (FOXO) is a mammalian homologue of DAF-16, which is known to regulate the lifespan of Caenorhabditis elegans and includes subfamilies of forkhead transcription factors such as AFX, FKHRL1, and FKHR," wrote K. Fukunaga and colleagues, Tohoku University.
"FKHR is phosphorylated on three sites (Thr-24, Ser-256, and Ser-319) in a phosphatidylinositol 3-kinase (PI3K)/Akt-dependent manner,...
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