Crohn Disease
Cholera toxin subunit B inhibits IL-12 and IFN-gamma in colitis and Crohn disease
Published in Health and Medicine Week, December 19th, 2005
"Cholera toxin B subunit (CT-B) is a powerful modulator of immune responses. [We] have previously demonstrated that oral administration of recombinant CT-B (rCT-B) is able to prevent and cure the Crohn disease (CD)-like trinitrobenzene sulfonic acid (TNBS) mediated colitis," researchers in Italy report.
According to E.M. Coccia and colleagues at the Istituto Superiore di Sanita in Rome, "In this study [we] extended [these] observations and examined if rCT-B interferes with the molecular signaling underlying the Th1 type response both in TNBS...
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