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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . February 27th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Bacteriology - Studies report 2 million Americans carry drug-resistant Staph bacterium

Cancer Research - Genetics research may hold key to destroying cancer cells

Diet & Nutrition - Scientists dispel late-night eating/weight gain myth

Sleep Disorders - Couples sleep study looks at link between snoring and marital satisfaction

Sudden Infant Death Syndrome - Doctors urged to talk to parents of preemies about SIDS risk

Acinetobacter Baumannii Outbreaks - Single clone Acinetobacter baumannii strain spreads in Turkey ICU

Acute Myeloid Leukemia - Impaired C/EBP alpha function contributes directly to AML development

Acute Myeloid Leukemia - Large population-based study examines risk for AML following Hodgkin lymphoma

Addiction Medicine - Alcohol and drug use disorders were associated with smoking in youth from Puerto Rico

Addiction Medicine - Depictions of substance use in reality television send mixed messages

Addiction Medicine - New findings in addiction medicine described

Addiction Medicine - Opioid withdrawal symptoms not associated with buprenorphine dose, formulation or plasma levels

Addiction Medicine - Study supports a flexible approach to methadone dosing

Adenomatous Polyposis - Pancreas-sparing duodenectomy found effective in treating familial adenomatous polyposis

Adenovirus Vector - Rabbit VH domain antibody polyspecific to c-Met and adenoviral knob protein is generated

Adverse Drug Reactions - Anticholinergic drugs linked to mental impairment in elderly people

Adverse Drug Reactions - Antidepressant use in pregnancy appears associated with neonatal withdrawal symptoms

Adverse Drug Reactions - Cisplatin may trigger retinal neovascularization

Adverse Drug Reactions - Osteonecrosis of the jaw in cancer occurred after treatment with bisphosphonates

Adverse Drug Reactions - Ototoxicity in children receiving platinum chemotherapy may impact academic and social development

Age-Related Macular Degeneration - European commission approves Macugen for treatment of all types of wet AMD

Alcohol Use - Fourteen or more alcoholic drinks per week are associated with lowest CAD risk

Allergy & Immunology - Mice lacking T-cell protein develop lupus-like disease

Allergy & Immunology - Mouse model identifies method to reduce migration of white blood cells in autoimmune disease

Allergy & Immunology - U.S. FDA approves Clarinex-D 12 Hour

Alopecia - Alopecia a frequent complication in women receiving tacrolimus after SPK transplantation

Alzheimer Disease - Apolipoprotein E4 is a potential therapeutic target for Alzheimer disease

Alzheimer Disease - Genetic factors important in development and timing of Alzheimer disease

Alzheimer Disease - Genomic regulation in microglia perturbs genes relevant to Alzheimer disease

Alzheimer Disease - Link discovered between long-term depression and changes in the AD brain

Amyotrophic Lateral Sclerosis - Low vascular endothelial growth factor expression may encourage neurodegeneration in mice

Anesthesia - Fentanyl reduced emergent agitation for developmentally disabled dental patients

Anesthesia - TransDermal Delivery System beta suitable for local anesthesia in venipuncture

Anesthesia - Use of Lanz endotracheal tube lowers intubation injury in dogs

Anesthesia - Using intrathecal morphine with remifentanil enhances post-OPCAB analgesia

Angina - U.S. FDA approves Ranexa

Angiology - Adverse CV influence of low testosterone may be mediated via vascular structure, function

Angiology - Combined iliac endovascular intervention, infra-inguinal reconstruction may reduce operative risk

Angiology - Nebivolol is novel beta-blocker with endothelium-derived NO enhancement benefit

Angiology - Normal capillaries regress upon vascular endothelial growth factor inhibition

Angiology - PPARgamma regulates Ang II-stimulated phosphatidylinositol 3-kinase

Angiology - Remodeling characteristics of minimally diseased coronary arteries are consistent

Angiology - Researchers provide details of new studies and findings in the area of angiology

Angiology - Rho kinase mediates endothelial tension development in microvascular leakage

Angiology - Skin cholesterol content identifies increased carotid intima-media thickness

Anthrax Vaccines - Adenovirus expressing B. anthracis antigen protects against anthrax

Anthrax Vaccines - Effects of storage on plasmid stability in Bacillus anthracis are reported

Anthrax Vaccines - Researchers report details of new studies and findings in the area of anthrax vaccines

Anti-Inflammatories - COX mechanisms play a role in maintaining pain hypersensitivity

Anti-Inflammatories - Nitric oxide mediates the anti-inflammatory activity of extracorporeal shock waves

Antibiotics - Continuing antibiotics is associated with failure of metronidazole for C. difficile-associated diarrhea

Antibiotics - In vitro, in vivo studies support development of pharmacodynamic parameters to determine drug dose

Antimicrobials - Report presents limitations of linear model for antimicrobial risk management

Antimicrobials - Second study to test persistency of chlorhexidine hand sanitizer commissioned in Europe

Anxiety - Anxiety and depression were associated with impaired work performance and safety

Anxiety - Depression severity unrelated to psychic and somatic anxiety components

Anxiety - Reduced perceived control were associated with anxiety sensitivity and agoraphobia

Apolipoproteins - Apolipoprotein domain identified that is responsible for fibronectin binding

Apoptosis - Arsenic trioxide is a novel human neutrophil pro-apoptotic agent

Apoptosis - Data advance knowledge in apoptosis research

Apoptosis - Findings advance knowledge in apoptosis research

Apoptosis - Flavonoids inhibited cell growth and induced apoptosis in osteosarcoma cells

Apoptosis - Inhibition of P13K/PKB signaling did not directly result in apoptosis in cancer

Apoptosis - Interferon gamma-inducible protein 10 inhibits tumor angiogenesis

Apoptosis - Mechanism by which diosgenin induces apoptosis in COX-2 deficient K562 described

Apoptosis - P73 regulation may have implications for neurological disease treatment

Apoptosis - Phorbol ester-induced apoptosis in prostate cancer cells involves protein kinase C delta

Apoptosis - Suppression of PKCalpha may contribute to hepatic apoptosis during sepsis

Apoptosis - VSOR Cl-channels are involved in H2 O2 -induced apoptosis in cultured mesangial cells

Apoptosis - p53 deficiency rescues apoptosis and differentiation of multiple cell types

Arthroplasty - Locked condylar plating effective for managing periprosthetic knee fractures

Arthroplasty - Serum IL-8 correlates with osteolysis after hip replacement

Arthroplasty - Trabecular metal acetabular cup show promise for revision total hip arthroplasty

Arthroplasty - Wound compression superior to drainage for reducing blood loss after hip replacement

Asthma - Children with asthma more likely to have behavior difficulties

Asthma - Exercise induced asthma impacts 1 in 6 Olympic athletes

Asthma - Indoor nitrogen dioxide levels affect asthmatic children in multi-family housing

Asthma - Some masks used in children's asthma treatment not effective

Asthma Therapy - Treatment with budesonide does not affect pregnancy outcome

Astrocytic Gliomas - TSC-22 protein expression is decreased in astrocytic gliomas

Atherosclerosis - Chest radiotherapy does not affect outcome of myocardial internal thoracic artery grafts

Atherosclerosis - Estradiol valerate plus levonorgestrel therapy reduces plasma trans-fatty acid

Atherosclerosis - Local vascular endothelial growth factor gene transfer may not prevent arterial restenosis

Atherosclerosis - New findings in the area of atherosclerosis detailed

Atherosclerosis - Reports describe recent advances in atherosclerosis research

Atherosclerosis - Threshold value may exist in atherosclerosis progression

Atherosclerosis Vaccines - Pathogen-accelerated atherosclerosis can be prevented by immunization

Attention Deficit Hyperactivity Disorder - Drugmaker provides update on regulatory status of Sparlon

Attention Deficit Hyperactivity Disorder - Novel assay detects therapeutic and illicit amphetamine enantiomers in hair and blood

Attention Deficit Hyperactivity Disorder - U.S. FDA accepts new drug application for NRP104 as treatment for ADHD

Avian Influenza - Applications of Hemopurifier expanded to include avian influenza

Avian Influenza - Avian influenza pandemic planning kit introduced for businesses

Avian Influenza - Avian influenza virus infections in humans are focus of review

Avian Influenza - Safety issues may hamper production of bird flu vaccine

Awards - Kaiser Foundation, CNN International announce new award for HIV/AIDS journalism in Africa

Awards - Online revenue cycle software for medical practices tops KLAS 2005 Report Card

Awards - Unbiased Systems Architecture, Inc. named best overall IT vendor in KLAS top 20 report

Bacillus Sepsis Outbreaks -  Bacillus species sepsis outbreak in neonatal ICU may be related to construction work

Bacteremia Outbreaks - Heparin flush cause of Ralstonia pickettii bacteremia outbreak in neonatal ICU

Bacteriology - Aerosol treatment reduced bacteria concentrations

Bacteriology - Mouse model reveals importance of type 1 interferons in fighting bacterial infection

Bacteriology - Polyphenols protect cells from Porphyromonas gingivalis, may be useful for enamel diseases

Barrett Adenocarcinomas - Hypermethylation and loss of GPx3 expression linked to Barrett adenocarcinomas

Barrett Esophagus - Expression pattern of morphogenesis genes in Barrett esophagus studied

Behavior Disorders - Comprehensive Behavioral Care expands services to Maryland and Washington, DC

Behavioral Medicine - Endocannabinoids and leptin may modulate hypothalamic circuits involved in feeding behavior

Behavioral Therapy - Brief relationship therapy was more cost effective than other therapies for alcohol addiction

Biomedical Engineering - Injectable nanofibers allow controlled protein delivery to myocardium

Biomedical Engineering - Site-directed immobilization of antibody fragments allows detection of C-reactive protein

Biomedical Engineering - Vancomycin-loaded CaPO4 cement may resolve osteomyelitis and prosthesis infection

Bioterrorism - Global effort needed to foresee, prevent potential misuse of advances in life sciences

Bioterrorism - Pharmaceutical firm responds to call for acute radiation syndrome therapy for U.S. forces

Bipolar Disorder - Course of bipolar disorder in children described for the first time

Bipolar Disorder - Rapid mood switching and suicidality studied in familial bipolar disorder

Bipolar Disorder - Women with bipolar disorder do not have a higher rate of depressive episodes than men

Birth Defects - Comprehensive global analysis identifies birth-defect trends

Bladder Cancer - Intravesical gemcitabine used to treat superficial transitional cell carcinoma

Bladder Cancer - New drug inhibited in vitro bladder cancer migration and invasion

Bladder Cancer - Polymorphism in hGPX1 gene may be used as marker for bladder cancer recurrence

Bladder Cancer - Research in bladder cancer provides new insights

Bone Development - Bone morphogenetic protein-15 helps regulate oocyte maturation

Bone Development - The peripheral cannabinoid receptor CB2 regulates bone mass

Bone Repair - U.S. FDA 510(k) clears Collagen-Mineral Composite Bone Graft Material

Brain Cancer - Molecularly targeted therapy for pediatric brain tumors discussed

Breast Cancer - Breast cancer marker receives diagnostic and therapeutic patent approval

Breast Cancer - Bright-field metallography assay detects HER2 status and protein expression in breast cancer

Breast Cancer - Coffee consumption may have protective effect on breast cancer risk in premenopausal women

Breast Cancer - Data advance knowledge in breast cancer research

Breast Cancer - Decreasing risk of breast cancer is seen for women engaged in physical activity

Breast Cancer - Different subcellular localizations of ERK2 implicated in breast cancer patient survival

Breast Cancer - Endometrial thickness in breast cancer patients is not associated with tamoxifen

Breast Cancer - Findings advance knowledge in breast cancer research

Breast Cancer - Findings describe new data in breast cancer research

Breast Cancer - Findings in breast cancer provide new insights

Breast Cancer - Flow technique could simplify targeting cancer therapy

Breast Cancer - Fluorouracil-epirubicin-navelbine deemed effective in advanced breast cancer

Breast Cancer - Guidelines for intraoperative assessment of the breast detailed

Breast Cancer - HER-1 and HER-2 overexpression linked to adverse prognosis in breast cancer

Breast Cancer - Histopathology of primary breast cancer in 2005 reviewed

Breast Cancer - Infrared breast scanner hits milestone of units in service free to qualified doctors

Breast Cancer - KiSS-1 expression is increased in human breast cancer

Breast Cancer - Local cancer recurrence minimized with breast conserving therapy

Breast Cancer - Long-term treatment recommended in breast cancer patients with severe radiation-induced fibrosis

Breast Cancer - Low-density microarray useful for rapid breast tumor analysis

Breast Cancer - Macrophages can initiate breast tumor angiogenesis

Breast Cancer - Mitomycin c and capecitabine used to treat metastatic breast cancer patients

Breast Cancer - New data illuminates research in breast cancer

Breast Cancer - New findings in the area of breast cancer described

Breast Cancer - New research in the area of breast cancer detailed

Breast Cancer - Ospemifene inhibited growth of dimethylbenzanthracene-induced mammary tumors

Breast Cancer - PIK3Ca mutations correlate with gene expression and drug sensitivity

Breast Cancer - Post-pregnancy tissue changes promote breast tumor metastasis

Breast Cancer - Prediction and prevention of breast cancer discussed

Breast Cancer - Pregnancy hormones may influence rate of women with postbirth breast cancer

Breast Cancer - Protein found to control tumor growth in certain breast cancers

Breast Cancer - Recent findings illuminate research in breast cancer

Breast Cancer - Recent studies add new data to breast cancer research

Breast Cancer - Reports add new data to breast cancer research

Breast Cancer - Researchers detail new studies and findings in the area of breast cancer

Breast Cancer - Researchers report details of new studies and findings in the area of breast cancer

Breast Cancer - Researchers' findings advance breast cancer research

Breast Cancer - Skin-sparing mastectomy does not change risks to breast cancer patients

Breast Cancer - Spiritually-based breast cancer education may be more effective than secular methods

Breast Cancer - Studies describe new findings in breast cancer research

Breast Cancer - Surgery best for controlling breast cancer in older women

Breast Cancer - Surgery of liver metastases performed with low morbidity and mortality in select breast cancer patients

Breast Cancer - Survey reveals deficiencies in management of cancer treatment-induced bone loss for women

Breastfeeding - Babies breastfed for 6 months have significantly fewer respiratory illnesses

Bronchopulmonary Dysplasia - U.S. FDA grants Surfaxin fast track designation for prevention and treatment of BPD

Brucellosis Vaccines - Researchers report details of new studies and findings in the area of Brucellosis vaccines

Business & Finance - Allergan extends expiration date of exchange offer

Business & Finance - Cancer drug developer posts net loss of $0.17 per share

Business & Finance - Cancer drug developer reports loss of $0.23 per share

Business & Finance - Company reports Q4 revenue of $132.7M, discusses remarketing of Tysabri

Business & Finance - Dialysis systems maker responds to Nasdaq notification

Business & Finance - Dionex reports record sales for the second quarter, meets guidance

Business & Finance - Drug delivery-focused company receives notice of AMEX delisting

Business & Finance - Drug development company subsidiary CDE certified for new market tax credit program

Business & Finance - Healthcare company announces transfer of manufacturing part of Erie operations to Mexico

Business & Finance - Hematology-focused biotech firm adopts shareholder rights plan

Business & Finance - Maker of blood oxygen monitoring system files registration for public equity offering

Business & Finance - Nanomaterials company uses $1.15 million grant and loan package to expand its subsidiary, ND Life

Business & Finance - Orthopedic surgical products company reports Q4 2005 net sales up 6% to $848 million

Business & Finance - Pharmaceutical company regains Nasdaq compliance

Business & Finance - Pharmaceutical company reports Q4 05 revenues of $437,000, down from $2.6 million in Q4 04

Business & Finance - Pharmaceutical company shareholders approve spinout of targeted immunotherapy assets

Business & Finance - Polymun development and manufacturing agreement sold for $1 million

Business & Finance - Protein, antibody developer reports net loss of $73.2M for 2005

Business & Finance - Specialty oncology company completes merger, raises $5.9 million in private financing

Business & Finance - Supplier of rapid pregnancy, ovulation tests to sell 3,400,000 shares of common stock

Business Expansion - First Colony Corp. launches healthcare affiliate, expands to Nashville office

Business Update - Acadia Healthcare announces new operation

Business Update - Agfa HealthCare awarded extensions on two Premier contracts

Business Update - Altus forms physician support company

Business Update - American CareSource completes implementation of client agreement

Business Update - American Healthways changes name to Healthways, Inc.

Business Update - CRO retains The Equity Group to provide investor relations services

Business Update - DNA-focused company expands licensing program, hires PatentBridge

Business Update - Healthcare compliance software provider posts Q4 contract sales of over $1.5 million

Business Update - Healthcare management software provider expands product lines and executive team

Business Update - Resuscitation device maker reports on deployment of equipment by EMS agencies

Business Update - Spacelabs receives $2.1 million order for patient monitoring equipment from hospital group

Business Update - Surgical products, services companies partner to target correctional health market

Business Update - Triad Hospitals finalizes joint venture with Akron General Health System

Business Update - Triad Hospitals finalizes joint venture with Tennessee-based Gateway Health System

Business Update - Wound care company strengthens its commercial organization to support growth strategy

Business Update - Zoll Medical signs 3-year contract with Novation for noninvasive cardiac support pump

Campylobacter Outbreaks - Precooked sausages cause of campylobacteriosis outbreak in New Zealand

Cancer Diagnostics - Diagnostic criteria and clinical implications of Gleason grading discussed

Cancer Diagnostics - Genetic testing used to diagnose pheochromocytoma or functional paraganglioma

Cancer Gene Therapy -  Spirulina platensis phycocyanin antitumoral activities are affected by CD59

Cancer Gene Therapy - AIM2 suppresses human breast cancer cell proliferation and mammary tumor growth

Cancer Gene Therapy - Adenovirus vector is more infective for esophageal and oral carcinoma cells

Cancer Gene Therapy - p27(KIP1) prolongs cell cycle and induces apoptosis in gastric cancer cells

Cancer Gene Therapy - p53 cDNA sequence mutations are introduced by a retroviral vector

Cancer Genetics - PKCalpha expression is regulated by Elk-1 and MZF-1 in hepatocellular carcinoma

Cancer Metastasis - Study shows tumors spread when blood vessel structural cell activity is limited

Cancer Research - Protein suppresses growth of head and neck tumors

Cancer Research - Structure of protein essential for promoting cancer development described

Cancer Research - Tobacco settlement aids research, returns substantial dividends to Pennsylvania's economy

Cancer Risk Factors - Cancer risk does not appear related to socioeconomic variation in Norwegian women

Cancer Risk Factors - Glucose transporter polymorphisms may increase susceptibility to clear-cell renal carcinoma

Cancer Screening - Pennsylvania governor proposes giving more women access to breast and cervical cancer screening

Cancer Survivors - Pathways for psychosocial care of cancer survivors discussed

Cancer Survivors - Prevalence of risky health behaviors among cancer survivors analyzed

Cancer Therapy - Advocacy might be a valuable strategy in cancer control

Cancer Therapy - Alemtuzumab induces caspase-independent cell death in lymphocytic leukemia cells

Cancer Therapy - Alternative regimens boost the efficacy of hypericin-photodynamic therapy

Cancer Therapy - Analysis of Genasense trial confirms major efficacy variables in patients with melanoma

Cancer Therapy - Cancer organization updates to several clinical practice guidelines

Cancer Therapy - Data advance knowledge in cancer therapy research

Cancer Therapy - Docking studies shed light on folate binding in cancer therapy

Cancer Therapy - Enrollment complete in pivotal phase III trial of FavId for follicular B-cell NHL

Cancer Therapy - Findings describe new data in cancer therapy research

Cancer Therapy - Gefitinib used to treat non-small cell lung cancer

Cancer Therapy - Gemcitabine and carboplatin used to treat non-small cell lung cancer

Cancer Therapy - High-dose therapy increased complete response rate in multiple myeloma patients

Cancer Therapy - Increased role for PET imaging could improve cancer care

Cancer Therapy - Lenalidomide and thalidomide exhibit distinct pharmacological profiles

Cancer Therapy - Magnetically labeled human natural killer cells are effective against osteosarcoma cells

Cancer Therapy - Monoclonal antibody therapy for cancer treatment is focus of review

Cancer Therapy - Multicenter phase II study with MKC-1 begins

Cancer Therapy - New findings in the area of cancer therapy detailed

Cancer Therapy - No evidence of gemcitabine accumulation during weekly administration detected

Cancer Therapy - Parathyroid hormone-related protein may be a target in immunotherapy for tumors

Cancer Therapy - Phase I trial of dendritic cell vaccine in patients with colorectal cancer meets endpoint

Cancer Therapy - Recent studies add new data to cancer therapy research

Cancer Therapy - Reovirus could be developed into an effective therapy for cancer

Cancer Therapy - Reports advance knowledge in cancer therapy research

Cancer Therapy - Research add new data to cancer therapy body of knowledge

Cancer Therapy - Researchers' work adds to cancer therapy body of knowledge

Cancer Therapy - Systemic chemotherapy produces antitumor activity for metastatic hepatocellular carcinoma

Cancer Therapy - TPA plus NF-kappaB may improve the therapeutic efficacy of TPA in some myeloid leukemia patients

Cancer Therapy - The small molecule inhibitor PS1145 targets activity in prostate cancer cells

Cancer Vaccines - Antitumor immunity was induced by epitopes linked to beta2 -microglobulin

Cancer Vaccines - Cancer vaccine peptides elicit skin reaction without anaphylaxis

Cancer Vaccines - Fusion of dendritic cells with osteosarcoma activates antitumor CTLs

Cancer Vaccines - Geron clarifies license rights for cancer vaccines

Cancer Vaccines - Imiquimod enhances dendritic cell survival and promotes T-cell priming

Cancer Vaccines - Monoclonal antibodies to IGF-II inhibit IGF receptor type I signal transduction

Cancer Vaccines - OX40 costimulation and GM-CSF whole-cell vaccination overcome tolerance to tumor antigen

Cancer Vaccines - Polyoma virus-like particles elicit cytokine responses in antigen-presenting cells

Cancer Vaccines - Report describes elements of analyzing T-cell immunity

Cancer Vaccines - Reports add new data to cancer vaccines research

Cancer Vaccines - Researchers describe findings in cancer vaccines studies

Cancer Vaccines - Studies advance knowledge in cancer vaccines research

Cancer Vaccines - TRICOM vector-based cancer vaccines are focus of review

Cancer Vaccines - p43 cytokine enhances IFN-gamma production in CD4+ T cells

Carcinogenesis - Domain functions of p63 isotypes regulate different aspects of epidermal homeostasis

Cardiac Arrhythmia - Cardiac Cryoablation System not approvable, U.S. FDA determines

Cardiac Regeneration - Evidence supports use of mesenchymal stem cells for cardiac regeneration

Cardiology - 16-slice MSCT suitable for monitoring of large coronary stents

Cardiology - A woman's waist measurement is a predictor of heart disease

Cardiology - Apex-to-base relaxation gradients may facilitate restoration of LV cavity in diastole

Cardiology - Avoiding microbubbles in RF ablation energy delivery yields best results

Cardiology - Beta-blockers remain a cornerstone of cardiovascular therapy

Cardiology - Coronary distal emboli particle size affects myocardial perfusion

Cardiology - Increase in QTc interval duration predicts mortality in heart transplant patients

Cardiology - Long Distance Corridor Walk provides valid estimate of peak VO2 in older adults

Cardiology - Most short-term heart rate variability measures are highly stable over time

Cardiology - New findings in the area of cardiology detailed

Cardiology - Novel steerable lead placement catheter enables direct His-bundle pacing

Cardiology - Reports add new data to cardiology research

Cardiology - Reports describe recent advances in cardiology research

Cardiology - Researchers provide details of new studies and findings in the area of cardiology

Cardiology - Researchers report details of new studies and findings in the area of cardiology

Cardiology - Researchers studied natural history of valvular regurgitation in anorexigen-treated subjects

Cardiology - Sirolimus-eluting stent may reduce re-blockage in complex coronary lesions, study shows

Cardiology - Studies add new findings to cardiology body of knowledge

Cardiology - Study compared mapping criteria for postinfarction ventricular tachycardia

Cardiology - Study found no differences in RF ablation between normal vs. scarred myocardium

Cardiology - T-wave ratio in 24-h ECG is an indicator of symptom history in long-QT syndrome

Cardiology - The role of GH in cardiovascular risk in aging and obese is reviewed

Cardiology - Thirty patients receive non-surgical replacement for diseased aortic heart valve

Cardiometabolic Disease - The role of insulin resistance in the cardiometabolic syndrome is reviewed

Cardiomyocytes - Beta-myosin heavy chain myocytes are more resistant to power output changes during ischemia

Cardiomyocytes - Human atrial cardiomyocytes express an outwardly rectifying chloride channel

Cardiomyocytes - Impaired coronary and myocardial flow in aortic stenosis is associated with apoptosis

Cardiovascular Disease - Cardiovascular benefits of nebivolol persist long after therapy withdrawal in rat model

Cardiovascular Disease - Caval division for partial anomalous pulmonary venous connection appears safe

Cardiovascular Disease - Clopidogrel with early interventional strategy is associated with low CV event rates

Cardiovascular Disease - Differences in disease presentation may require gender-specific therapy for heart disease

Cardiovascular Disease - Family CHD history is excluded from risk calculation in electronic health records

Cardiovascular Disease - Management of coronary heart disease is focus of review

Cardiovascular Disease - Nearly half of people who need cholesterol treatment don't get it

Cardiovascular Disease - Pharma company introduces heart disease campaign to help women with physician conversations

Cardiovascular Disease - Review focuses on diagnosis and screening of coronary artery disease

Cardiovascular Disease - Routine auscultation is valuable for pre-op detection of valvular heart disease

Cardiovascular Disease - Significant narrowings are present in septal branches in hypertrophic cardiomyopathy

Cardiovascular Disease - Single bolus dalteparin may be alternative to unfractionated heparin during PCI

Cardiovascular Disease - Socio-economically patterned access to medical care may be factor in SES and CVD relation

Cardiovascular Disease - Strategic sampling of NT-pro BNP concentration could inform management of ACS patients

Cardiovascular Disease - Study finds immune cells that protect against heart disease

Cardiovascular Disease - Thrombus formation, large plaque burden increase risk for transient no-reflow during PCI

Cardiovascular Disease - Urban U.S. black women underestimate heart disease risk

Cardiovascular Disease - Vascular or mixed hemodynamic profile measured during lab stress may be CVD risk marker

Cardiovascular Research - Engineered heart tissue offers insights into irregular heartbeats

Cardiovascular Research - Heart-type fatty acid-binding protein is an early marker of myocardial injury

Cardiovascular Therapy - Phase III study examines ability of drug to slow atherosclerosis

Cataract Surgery - Silicon contamination may promote calcification of hydrophilic acrylic IOLs

Central Nervous System - Glutamate receptor agonist may be an effective tool for investigating stress-related CNS disorders

Cervical Cancer - HPV-18 and -45 E7 proteins can be detected in cervical carcinoma biopsies

Cervical Cancer - HPV-DNA testing may be more sensitive than repeat cytology for predicting cervical intra-epithelial neoplasia

Cervical Cancer - Laparoscopic staging enhances treatment planning for women with advanced cervical cancer

Cervical Cancer - Nude rat is orthotopic model for cervical cancer

Cervical Cancer - RT-CHT resulted in prolonged suppression of NK-cells and T-suppressor cells

Cervical Cancer - Researchers' data advance cervical cancer research

Cervical Cancer - Review examines strategies for recruiting participants into cervical cancer screening trials

Cervical Cancer - Sentinel lymph node mapping/biopsy may aid detection of early cervical cancer

Cervical Cancer - Serum hemoglobin is prognostic indicator of neoadjuvant response to chemotherapy

Cervical Cancer Risk Factors - Human leukocyte antigen-A allele alters cervical cancer risk in Chinese women

Cervical Cancer Risk Factors - Study identified human papillomavirus type for adenocarcinoma and squamous cell carcinoma

Cervical Carcinoma - Cell death occurs independent of apoptosis signals in cervical squamous cell carcinoma

Charcot-Marie-Tooth Disease - Gene mutation discovered that causes rare form of inherited nerve disorder

Chemotherapy - Findings describe new data in chemotherapy research

Chemotherapy - Paclitaxel pharmacokinetics and effect in patients with advanced cancer studied

Childhood Cancer - Long-term outcomes of adult survivors of childhood cancer reviewed

Chronic Hepatitis C Virus - Interferon therapy is efficient in elderly patients with chronic hepatitis C

Chronic Obstructive Pulmonary Disease - Diurnal noninvasive ventilation beneficial in hypercapnic COPD

Chronic Obstructive Pulmonary Disease - Emotional burden of COPD may make patients reluctant to seek treatment, survey shows

Chronic Peritoneal Dialysis - Increasing chronic peritoneal dialysis cycles has low impact on phosphate removal

Cirrhosis - A model accurately predicts severe fibrosis or cirrhosis in chronic hepatitis C

Cirrhosis - Bilirubin might be a marker for sleep apnea syndrome and early stage cirrhosis

Clinical Trials - Blood cancer patients not directed by their specialists to clinical trials, survey shows

Clinical Trials - ComfortScan maker provides update

Clinical Trials - Enrollment opened in phase 2 trial of DNA vaccine against cytomegalovirus

Clinical Trials - Investigational New Drug Application filed to test safety of anticancer compound IT-101

Clinical Trials - Medical centers vary in disclosing conflicts of interest to clinical trial subjects

Clinical Trials - Microbiologic surrogate end points in otitis media trials are evaluated

Clinical Trials - Patient treatment begun in phase 1 clinical trial of anticancer cell-cycle inhibitor

Clinical Trials - Phase 2 program of antisense drug in patients with familial high cholesterol initiated

Clinical Trials - Plans for phase 2 trial of anticancer agent in elderly poor-risk AML patients announced

Clinical Trials - Report announces the MICHELANGELO OASIS-5 trial evaluating fondaparinux

Clinical Trials - TopoTarget, partner, initiate phase II clinical trial of PXD101 for T-cell lymphomas

Clinical Trials - WAVE trial to determine if oral anticoagulation improves on antiplatelet therapy alone

Clostridium Vaccines -  Clostridium haemolyticum phospholipase C elicits protective immunity in guinea pigs

Collaborations - ASI selected to deliver integrated consumer-directed healthcare solution

Collaborations - Abbott Laboratories grants rights for new cancer and transplantation drug tests

Collaborations - Advanced gene expression service provider expands globally

Collaborations - Alliance signed for promotion and support of clinical trials

Collaborations - Biosciences company, Bristol-Myers Squibb extend the term of research agreement

Collaborations - Cellomics and Evotec to collaborate on cell-biology solutions for life-science markets

Collaborations - Collaboration formed to provide primate-human gene expression and SNP assays

Collaborations - Collaboration to develop ophthalmic therapeutics built from synergistic drug combinations

Collaborations - Commercialization deal signed for atherosclerosis treatment

Collaborations - Deal signed in Taiwan for development of Immunogene therapy for cancer indication

Collaborations - Imaging services company announces partnerships with Meridian Health and Red Bank Radiology

Collaborations - Johnson Controls joins in effort to integrate disparate healthcare technologies

Collaborations - Licensing and commercialization agreements expanded into Europe for IGN311

Collaborations - Locus announces research agreement with Eli Lilly and Company for protein kinase target

Collaborations - Louisiana court partners with Southern University to evaluate substance abuse protocols

Collaborations - Partners form joint Center for Systems and Computational Biology

Collaborations - Partnership forged to develop new solutions for assessing drug toxicity

Collaborations - Partnership formed to develop RNAi therapeutics for childhood cancer

Collaborations - Research and development collaboration with Astellas Pharma extended

Collaborations - Study to evaluate research-stage diagnostic test to detect high-grade PIN

Colon Cancer - Disease-free survival after 3-year follow-up proposed as end point for colon cancer clinical trial

Colon Cancer - Expression of licensing factors, Cdt1 and Geminin in human colon cancer examined

Colon Cancer - New research in the area of colon cancer detailed

Colon Cancer - Open colon surgery for colon carcinomas deemed not problematic

Colon Cancer - Oral endostatin therapy does not significantly affect colon tumors

Colon Cancer - Physician recommendation may improve adherence to colorectal screening in minority women

Colon Cancer - SL4 cells used to study mechanism of hepatic metastasis of colon carcinoma cells

Colorectal Cancer - Colorectal cancers from the Middle East had different gene mutation frequencies

Colorectal Cancer - Fluorouracil-based chemotherapy does not improve survival among MSI-H patients

Colorectal Cancer - Identification of hiatus ligament needed to achieve laparoscopic total mesorectal excision

Colorectal Cancer - Nine or more lymph nodes should be examined in Dukes B colorectal cancer

Colorectal Cancer - Nitric oxide does not change colorectal cancer risk

Colorectal Cancer - Prognosis for colorectal metastases improved by major hepatectomy after portal vein embolization

Colorectal Cancer - Radical surgery used to treat T1 and T2 stage colorectal cancer patients

Colorectal Cancer - Research in colorectal cancer provides new insights

Colorectal Cancer - Risk of colorectal cancer may be reduced with higher dietary folate/vitamin B6 intake

Complementary & Alternative Medicine - A green tea extract cocktail with amino acids impedes tumor angiogenesis

Complementary & Alternative Medicine - Alternative medicine use is not uncommon following genetic testing results for BRCA1/2

Complementary & Alternative Medicine - Curcumin blocks the angiogenic capacity of endothelial cells

Complementary & Alternative Medicine - Danish agency decides medical products with ciclosporin may be substituted with caution

Complementary & Alternative Medicine - Fermented soy milk intake lowered cholesterol and TG liver buildup under oxidative stress

Complementary & Alternative Medicine - Laserpitin lowers hepatic triglyceride content in stroke-prone spontaneously hypertensive rats

Complementary & Alternative Medicine - Mindfulness-based stress reduction better for mood improvement, massage better for pain

Complementary & Alternative Medicine - Nutrition knowledge is linked to higher weight loss in obese and overweight low-income mothers

Complementary & Alternative Medicine - Perioperative magnesium doesn't prevent post-OPCAB atrial fibrillation

Complementary & Alternative Medicine - Vitaline Smart Q10 shown to be safe and well-tolerated

Contracts - Company focused on persons with special needs wins labor contract

Contracts - Dialysis products manufacturer signs Canadian distribution agreement with Genpharm, Inc.

Contracts - Patient monitoring technology company signs 3-year agreement with Novation

Contracts - Proteomics company retains Glocap Advisors as financial advisory firm

Corneal Infections -  Pseudomonas vaccine elicits passive protection against corneal infection

Coronary Artery Bypass - Researchers report details of new studies and findings in the area of coronary artery bypass

Coronary Heart Disease - Diabetes increases risk of heart disease, even in women without prior cardiovascular events

Coronary Stenting - Heparin coronary stent coating may not reduce thrombosis risk

Critical Care Medicine - Chest re-exploration in ICU can be alternative to returning to operating theater

Critical Care Medicine - Noninvasive ventilation improves outcome of acute cardiogenic pulmonary edema

Critical Care Medicine - S-enantiomer of albuterol does not affect airway secretions in long-term intubated patients

Cyclosporin - Cyclosporin monitoring improves therapy in early and late stages post-transplantation

Cystic Fibrosis - Cationic lipid mediated gene transfer is inhibitory in CF tracheal gland cells

Cystic Fibrosis - Denufosol proceeding to phase III trials in cystic fibrosis

Cytokines - Splenocyte cytokines are induced by heat shock proteins and concanavalin A

Cytomegalovirus - Valcyte did not protect against CMV infection in liver transplant recipients

DNA Regulatory Sequences - Study finds 60 new genes controlled by DNA snippet

DNA Research - New anthracycline is more cytotoxic than a structurally related predecessor

DNA Research - Single-step, single-nucleotide polymorphism typing based on DNA hole transport achieved

DNA Research - Transcriptional activation is stimulated by bidirectional RNA polymerase II elongation

DNA Vaccines - Studies advance knowledge in DNA vaccines research

Dengue Virus - Biologists visualize protein interaction that may initiate dengue virus infection

Dengue Virus Vaccines - DNA vaccine protects mice against Dengue type 2 virus

Dental Health - Nation's dentists partner with bottled water brand for pediatric fluoride education program

Dental Health - Pennsylvania dental organization launches kid-friendly dental web site

Depression - Better access to primary care linked to improved care for patients with depression

Depression - Findings advance knowledge in depression research

Depression - Gene therapy used to prevent depression in mice

Depression - Individual illness characteristics are predictive of treatment expectations

Depression - Women with major depression at risk of relapse during pregnancy without medication

Dermatology - Report examines safety and efficacy of sunscreen products

Dermatology - Research may point to diagnostic tests for women predisposed to stretch marks

Dermatology - Survey shows majority of Americans did not know that OTC products can make scars worse

Developmental Biology - Crescent modulates Wnt signaling in early Xenopus embryogenesis

Developmental Biology - Gata 3 expression is needed for nephric duct formation in the developing kidney

Developmental Biology - Rac1 activation by RhoG regulates cell migration

Diabetes Complications - Angiotensin-converting enzyme is linked to angiogenic factors in diabetic retinopathy

Diabetes Complications - Diabetes alters bone gene expression, which may affect beta-cells and bone formation/resorption

Diabetes Complications - Elevated alpha-crystallin expression in STZ-induced diabetic rats leads to complications

Diabetes Complications - Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats

Diabetes Complications - Review discusses the impact of diabetes on cognition

Diabetes Complications - SR58611A improves wound healing in diabetic animal models

Diabetes Complications - STZ-induced diabetes may offer protection against cyclosporine A-induced renal dysfunction

Diabetes Complications - Taller patients with diabetes have higher risk of foot or leg amputation

Diabetes Complications - mTOR signaling inhibition with rapamycin eases renal hypertrophy in early diabetic mice

Diabetes Control - Poor control of diabetes found in large sample of Canadian patients

Diabetes Control - Studies evaluate quality of care for patients with diabetes

Diabetes Diagnostics - Modern classification methods for diabetes in young adults are discussed

Diabetes Diagnostics - New imaging technology detects subtle changes in brains of type 1 diabetics, study shows

Diabetes Drugs - Approval and availability of Avandaryl (rosiglitazone maleate and glimepiride) announced

Diabetes Epidemiology - Study identifies the spectrum of insulin sensitivity in the Korean population

Diabetes Management - Case management decreases diabetic retinopathy risk in patients with type 2 diabetes

Diabetes Pathogenesis - Diabetic youth demonstrate insulin resistance but retain first-phase insulin response

Diabetes Pathogenesis - High PCO, AOPP, and LHP levels in those with poor glycemic control may lead to complications

Diabetes Pathogenesis - Insulin and oleic acid raise PPARgamma2 expression in cultured mouse hepatocytes

Diabetes Pathogenesis - Leptin inhibits stimulation of fatty acid uptake by insulin in differentiated adipocytes

Diabetes Pathogenesis - Neuronal insulin signal transduction mechanisms may be disrupted in diabetes phenotypes

Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis described

Diabetes Pathogenesis - Overexpression of the coactivator Bridge-1 results in insulin deficiency and diabetes

Diabetes Pathogenesis - PI3K signaling pathway inhibition leads to lower insulin-stimulated adiponectin secretion

Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights

Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis

Diabetes Pathogenesis - Researchers publish new studies and findings in the area of diabetes pathogenesis

Diabetes Pathogenesis - Researchers' data advance diabetes pathogenesis research

Diabetes Pathogenesis - Semicarbazide-sensitive benzylamine oxidase expression controls methylamine hypophagia

Diabetes Pathogenesis - Tripalmitin shows adverse physicochemical properties in beta cells

Diabetes Pathogenesis - Vaspin gene expression in adipose tissue may be related to obesity and diabetes

Diabetes Research - Article indicates drug target RIP140 controls insulin sensitivity and glucose tolerance

Diabetes Research - Model for myocardial infarction and heart failure in db/db diabetic mouse is developed

Diabetes Research - Nitric oxide scavenger AMD6221 augments cardiac response to noradrenaline in rat model

Diabetes Risk Factors - Guidelines are needed for preventing diabetes from antipsychotic use

Diabetes Therapy -  Shakuyakukanzoto effect in diabetics may rely on descending noradrenergic neuron activation

Diabetes Therapy - Heat tolerance improves in diabetics when taking rosiglitazone for glycemic control

Diabetes Therapy - KCP256 shows lower drug-induced hypoglycemia risk compared with sulfonylurea drugs

Diabetes Therapy - Long-term treatment with novel GSK-3 inhibitor improves glucose homeostasis in ob/ob mice

Diabetes Therapy - MIRE did not improve sensation in diabetes related peripheral neuropathy

Diabetes Therapy - New data illuminates research in diabetes therapy

Diabetes Therapy - Researchers provide details of new studies and findings in the area of diabetes therapy

Diabetes Therapy - Rosiglitazone improves exercise capacity in individuals with type 2 diabetes

Diabetes Therapy - Studies add new findings to diabetes therapy body of knowledge

Diabetes Therapy - Studies advance knowledge in diabetes therapy research

Diabetic Retinopathy - Intravitreal hepatocyte growth factor reflects fibrotic processes in diabetic eyes

Diagnostics - 99mTc-sestamibi scintigraphy shows myeloma activity in bone marrow

Diagnostics - A new radioreceptor assay detects signs of angiogenic inhibition in preclinical models

Diagnostics - Analysis of regional wall motion abnormalities shows interobserver variability

Diagnostics - Anti-lipoarabinomannan antibody test detects latent TB in hemodialysis patients

Diagnostics - Cataracts can cause false positives on frequency doubling perimetry screening for glaucoma

Diagnostics - Contrast-enhanced subharmonic imaging may have use in perfusion assessment

Diagnostics - Denver firm inks agreement with Roche Diagnostics to expand molecular medical lab testing

Diagnostics - Dynamic contour tonometry suitable for use in assessment of glaucoma severity

Diagnostics - ECG and natriuretic peptide tests have comparable accuracy in LVSD diagnosis

Diagnostics - Elevated mycobacterial serine protease antibodies are active TB marker

Diagnostics - Endobronchial US-guided TBBX detects fluoroscopically invisible solitary pulmonary nodules

Diagnostics - Equipment and environment have little impact on speech-in-noise audiometry results

Diagnostics - Fibrotest accurately diagnoses HCV in hemodialysis and renal transplants

Diagnostics - First large order of HIV tests from Uganda since national protocol designation completed

Diagnostics - Gastroesophageal reflux disease is most common esophageal disease associated with noncardiac chest pain

Diagnostics - Human-blind probes and primers distinguish dengue virus serotypes

Diagnostics - I-MIBG scanning improves pheochromocytoma test accuracy

Diagnostics - Label change granted for Thyrogen

Diagnostics - Malignancy-associated changes in buccal mucosa cells may enable noninvasive screening

Diagnostics - Mitral leaflet separation index facilitates mitral stenosis assessment

Diagnostics - Parameters improve LV hypertrophy detection in resistant hypertension

Diagnostics - Parathyroid hormone testing predicts post-thyroidectomy hypocalcemia

Diagnostics - Production agreement inked with ASKION to produce MelaFind imaging device

Diagnostics - Pulmonary tuberculosis diagnosed in child presenting with acute hemoptysis

Diagnostics - Quantum dots detect early cervical cancer

Diagnostics - Recent studies add new data to diagnostics research

Diagnostics - Researchers publish new studies and findings in the area of diagnostics

Diagnostics - Researchers report details of new studies and findings in the area of diagnostics

Diagnostics - Serum DNA methylation markers useful in thyroid tumor diagnosis and monitoring

Diagnostics - Subset of patients may benefit from inclusion of bone biopsy into diagnostic procedure

Diagnostics - Utility of CT scans determined in nontuberculous mycobacterial infection

Diagnostics - Utility of three diagnostic tests for acute pancreatitis compared

Diagnostics - Vector magnetometers improve standardization of fetal MCG waveforms

Diagnostics - Wavefront system predicts post-LASIK night vision symptoms

Dialysis - Hematopoietic response to recombinant erythropoietin is modulated in dialysis

Dialysis - Levocarnitine therapy is justified in selected dialysis patients

Diet & Nutrition - Beef tallow increases linoleic acid potency in reduction of mammary tumor metastasis

Diet & Nutrition - Carbohydrate control achieved short-term weight loss but increased saturated fat intake

Diet & Nutrition - College freshmen susceptible to weight gain, but not always 15 pounds

Diet & Nutrition - Dairy-based high-calcium diet raised fat oxidation under acute energy deficit conditions

Diet & Nutrition - Dietary protein type and fat level can augment body fat-reducing activity of CLA in rats

Diet & Nutrition - Fortified chocolate is good for the heart, but there is a catch

Diet & Nutrition - IMCL content and changes favoring fat storage in muscle increased after high-fat feeding

Diet & Nutrition - Leptin secretion a strong predictor of long-term body fat accrual on a high-fat diet

Diet & Nutrition - Nutrition-/diet-induced changes in gene expression in white adipose tissue are reviewed

Diet & Nutrition - Nutritional therapy is a component of treatment of CVD in dyslipidemic patients

Diet & Nutrition - Older adults are vulnerable to adverse effects of dietary fat and to various forms of dementia

Diet & Nutrition - Palm oil replacement with polyunsaturated vegetable oil may lower myocardial infarction risk

Diet & Nutrition - Researchers' data advance diet & nutrition research

Diet & Nutrition - Retailer launches Women's Ultra Mega Bone Density supplement

Diet & Nutrition - Serum folate concentrations have decreased despite folic acid fortification in foods

Diet & Nutrition - Single nutrition session improves short-term clinical outcomes for chronic diseases patients

Diet & Nutrition - Soy's cardiovascular benefits may be overestimated

Disease Associations - Childhood poverty doubles obesity risk among black women

Disease Associations - Eotaxin and eotaxin mRNA levels in visceral adipose tissue were raised in obese

Disease Associations - Fruit fly research reveals potential connection between dementia and cancer

Disease Associations - Functional polymorphism identified in polycystic ovary syndrome

Disease Associations - High blood pressure, kidney disease increase heart disease risk in older Americans

Disease Associations - Increased pulse wave velocity, diastolic BP are demonstrated in subclinical hypothyroidism

Disease Associations - Increased risk of intestinal cancer studied in patients with Crohn disease

Disease Associations - Mild renal insufficiency is linked to reduced coronary flow in nonobstructive CAD patients

Disease Associations - Natural killer cells are immunoselected that lack stress-inducible ULBP

Disease Associations - Patients with vasculogenic erectile dysfunction should be evaluated for silent CAD

Disease Associations - Population-based study finds no link between prior myocardial infarction and dementia

Disease Control - Hospital guidelines/news media were information sources for doctors staffing SARS hotline

Disease Control - Massive quarantine effort helped control SARS epidemic in Singapore

Domestic Violence - Case-based online CME helps improve physician education in domestic violence

Doxorubicin - Doxoform suspected as a prodrug for doxazolidine

Drug Abuse - Chiropractors remind parents to discuss steroid abuse with young athletes

Drug Delivery - Age and tumor type influence transdermal fentanyl absorption in cancer pain patients

Drug Delivery - Biodegradable periodontal intrapocket device effective for antibiotic delivery

Drug Delivery - European Commission approves IONSYS

Drug Delivery - Findings describe new data in drug delivery research

Drug Delivery - In vitro tests support feasibility of transdermal iontophoretic triptorelin delivery

Drug Delivery - Novel HPLC assay developed for measuring atorvastatin in plasma

Drug Delivery - Novel dehydration-rehydration liposome vesicles show promise in antibiotic delivery

Drug Delivery - Same-day initiation of contraceptive patch does not improve continuation rates

Drug Delivery - Scientists characterize hot-melt extruded poly(ethylene oxide) films

Drug Delivery - Subcutaneous microsphere injection effective for sustained clonazepam release

Drug Delivery - Terpene enhancers improve transdermal selegiline delivery in vitro

Drug Development - APEX-AMI pexelizumab trial to complete enrollment in March

Drug Development - Access to investigational chickenpox product expanded to meet U.S. supply

Drug Development - Apoptosis induced by plant alkaloid sampangine in human HL-60 leukemia cells

Drug Development - Arixtra administered the morning after orthopedic surgery prevented VTE

Drug Development - Biologics license application for cervical cancer vaccine is on track

Drug Development - CD46-transgenic mice were used to study replication-incompetent adenoviral vectors

Drug Development - Data on Phenserine and Posiphen for Alzheimer disease to be presented in Geneva

Drug Development - Dendritic cell immaturity during infancy impairs vaccine-specific T-cell memory

Drug Development - Dengue proteins offer limited protection to interferon-deficient mice

Drug Development - Diphtheria toxin-mediated antigen delivery into dendritic cells stimulates CD8+ T cells

Drug Development - Dosing cycle completed on first patient in phase I trial of blood cancer drug

Drug Development - Dr. Gerald Yakatan joins allergy company's board of directors

Drug Development - Drugmaker provides CIP-Tramadol Extended Release update

Drug Development - European Design Examination Certificate granted for wound care management product

Drug Development - Good bioavailability reported from phase I trial of iclaprim

Drug Development - Hepatitis C candidate moves into preclinical development

Drug Development - Human T cell leukemia virus type 1 protease is target for anticancer drug design

Drug Development - IND application filed for anticancer drug with nanotechnology delivery platform

Drug Development - Icon retained for phase II/III trial for MBP8298 to treat multiple sclerosis

Drug Development - LgsKO mice show higher glucose tolerance and lower adiposity without fasting hypoglycemia

Drug Development - Lundbeck, collaborator to discover allosteric modulators of G-protein coupled receptors

Drug Development - Maryland Industrial Partnerships program approves 14 university-based research projects

Drug Development - Method is developed for generation of monoclonal antibody against SNEV protein

Drug Development - NDA submitted to U.S. FDA for involuntary emotional expression disorder therapy

Drug Development - New subsidiary to accelerate RNAi therapeutics programs

Drug Development - Novel boronated derivatives of 5,10,15,20-tetraphenylporphyrin developed

Drug Development - Pharma company in phase II trials of therapeutic for wet AMD

Drug Development - Pharma company initiates clinical trials of antisense drug in cancer patients

Drug Development - Pharma company receives milestone payment from Merck for ubiquitin ligases research

Drug Development - Pharmaceutical firm focused on diseases of aging and diabetes provides clinical pipeline update

Drug Development - Pharmacological improvements may help KRN633 beat diseases related to pathological angiogenesis

Drug Development - Phase I trial initiated with c-Met inhibitor in patients with multiple metastatic tumors

Drug Development - Phase I trial of Type 2 diabetes drug initiated

Drug Development - Phase I trial underway of skin patch for prevention of chemo induced emesis

Drug Development - Phase II trial of Hematide initiated in patients with anemia associated with cancer

Drug Development - Phase II trial of MF101 launched for treatment of menopausal symptoms

Drug Development - Positive results reported in phase III study of Entereg in postoperative ileus

Drug Development - Predictive modeling software company introduces new product for pharma companies

Drug Development - Prescription product with nutritional components for osteoarthritis introduced nationally

Drug Development - Study investigated effect of bacterial CpG DNA on immune system organs

Drug Development - Switching cytokine treatment induces monocyte differentiation into dendritic cells

Drug Development - Synthetic heparin could replace animal-derived anticoagulant

Drug Development - The new agent DN-9693 alters VEGF induction of connective tissue growth factor

Drug Development - U.S. FDA grants final approval for testosterone gel 1% product

Drug Development - U.S. FDA grants orphan medicinal product designation for rare disease protein therapeutic

Drug Development - U.S. FDA requests additional data for Delta opioid agonist; application on hold

Drug Interactions - Isoniazid-rifampin caused most adverse events in an outpatient study

Drug Resistance - Drug resistance may travel same path as quorum sensing

Drug Resistance - New findings in the area of drug resistance described

Drug Resistance - Routine screening for antiplatelet drug resistance should not yet be standard practice

Drug Safety - Chain-owned pharmacies less likely to provide prescription label translations

Drug Safety - Report on drug withdrawal in U.S. notes effect on selective COX-2 inhibitor market

Duodenal Cancer - Long-term results of radical resection for duodenal adenocarcinoma found positive

Echocardiography - Real-time transthoracic 3-dimensional ECG is feasible for volumetric analysis of abnormal LV

Echocardiography - Report presents an ECG LV wall area index for myocardial injury detection

Echocardiography - Report presents an ECG study of diastolic function in young patients with beta-thalassemia major

Electrocardiography - Electrocardiogram is a valuable tool in the primary care office

Electrocardiography - Electrocardiographic manifestations of noncoronary heart disease are focus of review

Electronic Medical Records - ConnectiCare to promote electronic health records with iHealthRecord

Electronic Medical Records - Family Health Center of Battle Creek selects EMR system to improve patient care

Embryonic Stem Cells - Scientists identify key protein involved in cell specialization process

Emphysema - Elastin fragments drive emphysema

Emphysema - Many emphysema patients would find lasting benefit from lung surgery

Endocrinology - Amygdala plays a role in regulating emotionality through glucocorticoids

Endocrinology - Effects of increased plasma ghrelin levels on metabolism and endocrine system are studied

Endocrinology - Estradiol stimulates vaginal Candida albicans through a ligand-binding mechanism

Endocrinology - Insulin upregulates angiogenic protein in regenerating livers after partial hepatectomy

Endocrinology - Newly discovered brain hormone puts brakes on reproduction

Endocrinology - Research reveals complexities of obesity/cortisol interactions

Endometrial Cancer - Aurora B expression used as predictor of poor prognosis in endometrial carcinoma

Endometrial Cancer - Gynecologic specialization may not affect survival in women with endometrial cancer

Endometrial Cancer - Tumor size may not independently predict recurrence in endometrial cancer

Endometriosis - Cytotoxic activity determined by endometrium may play role in development of endometriosis

Endometriosis - Endometriosis can cause symptoms after menopause

Environmental Health - Plasma Converter System in production at distributor PlasTech, New South Wales, Australia

Enzymology - Chymase-positive cells increase the angiogenic burden of gastric cancer

Enzymology - Protein related to vaccinia virus methyltransferase is involved in Trypanosoma cap 4 modification

Epidemiology - Discrepancy in acquired immunity against influenza is found between children and adults

Epidemiology - Filter-paper blood samples are useful for sero-epidemiology in developing countries

Epidemiology - Influenza immunization in children reduces influenza illnesses of unvaccinated elderly

Epidemiology - MTB strain analysis from four geographic sites indicates a clonal population structure

Epidemiology - Migration of AIDS patients has little impact on destination health care services

Epidemiology - Modeling strategies for statistical issues in life course Epidemiology are examined

Epidemiology - Nutrition researchers dispute claims that obesity problem is exaggerated

Epidemiology - Obesity epidemic will likely lead to increase in metabolic syndrome prevalence

Epidemiology - Prevalence of Staphylococcus aureus nasal colonization is high in U.S.

Epidemiology - Report examines prevalence of hepatitis A virus infection in U.S. population

Epidemiology - Tuberculosis dynamics linked to economic growth

Epidemiology - Valley fever disease incidence associated with antecedent climate conditions

Epstein-Barr Virus - New data illuminates research in Epstein-Barr virus

Escherichia Coli Vaccines -  Escherichia coli vaccine strain is safe and immunogenic in healthy adults

Escherichia Coli -  Escherichia coli O157 survival varies according to type of metal surface

Esophageal Adenocarcinoma - Impact of operative volume assessed after esophagectomy

Esophageal Adenocarcinoma - Neoadjuvant and adjuvant chemotherapy for esophageal adenocarcinoma discussed

Esophageal Cancer - Barrett esophagus and gastroesophageal reflux disease linked to higher mortality rates

Esophageal Cancer - Use of neoadjuvant chemoradiation in squamous cell carcinoma of the esophagus examined

Facilities - Aptamer-based therapeutic developer moves to new headquarters

Facilities - Brain monitoring device developer signs lease agreement for new headquarters facility

Facilities - Critical Care Systems opens branch pharmacy featuring on-site ambulatory infusion suite

Facilities - Healthcare management systems company to open fifth medical facility in California

Facilities - Lifeline Biotechnologies to relocate Florida facilities to Boston, Massachusetts

Facilities - Maximum Performance, MSKCC execute energy management/monitoring agreement

Facilities - Medical staffing company plans to add 20 investor-backed offices

Facilities - Pacific Coast Imaging and Heart Institute opens in Newport Beach

Facilities - Pharma company divests AWD.pharma manufacturing plant in Dresden, Germany

Facilities - Sigma-Aldrich Group member forms entity to provide raw manufacturing materials

Facilities - Sunnylife Global accepts investment commitment to finance first hospital permit costs

Facilities - Supplier of materials for personal care products to close Georgia films plant

Facilities - Swedish Covenant Hospital to expand emergency department at north side Chicago facility

Fetal Medicine - Pro-inflammatory cytokines inhibit placental 11beta-hydroxysteroid dehydrogenase type 2 activity

Finance - Adult-stem-cell company receives $11.0 million milestone payment from Olympus-Cytori

Finance - Allied Healthcare International reports 12.4% decrease in revenue

Finance - Allion Healthcare completes sale of 5M plus shares

Finance - Alzheimer's Foundation seeks grant applications for innovative care

Finance - Amedisys updates 2006 guidance

Finance - American HealthChoice's 1Q net patient billings increase 20%

Finance - Analytical instruments company reports Q4 2005 revenue growth of 21%

Finance - Biopharmaceutical company focused on metabolic diseases files shelf registration statement

Finance - Biopharmaceutical company reports 2005 U.S. and Canada net sales of anti-HIV drug up 32%

Finance - Biophysical analysis technology developer reports earnings per share of $0.02

Finance - Biotech company receives $1.4 million NIH grant to develop nano-scale X-ray microscope

Finance - Breathmeter maker raises $2.9 million to continue commercialization of sensors

Finance - Canadian biopharmaceutical firm reports 9% increase in revenue

Finance - Cancer drug developer reports loss of $0.99 per share, provides clinical pipeline update

Finance - Cancer immunotherapies developer receives delist determination from NASDAQ panel

Finance - Cancer vaccine developer completes $3M institutional financing

Finance - Cancer-focused biotech firm announces put option

Finance - Cancer-focused biotechnology company sets IPO of common stock at $6 per share

Finance - Cardiac device maker reports 10% increase in revenue

Finance - Cardiovascular products company reports record Q4 revenue, 2005 revenues up 17% to $202 million

Finance - Cardiovascular technologies company reports Q4 2005 net revenue of $38.6 million

Finance - Chemically derived drug distributor posts decline in revenue

Finance - Coagulation monitoring systems maker reports Q1 revenue up 112%

Finance - Company focused on age-related macular degeneration receives investment

Finance - Connecticut to receive mental health state incentive grant of $13.6 million over 5 years

Finance - Consumer products company announces earnings per share of $.72 for quarter

Finance - DNA-focused biopharmaceutical company files $70 million shelf registration

Finance - Developer of radiation therapy device records $1.1 million in sales in fiscal 2006 Q1

Finance - Diagnostic tests maker raises $8.25M in Series C financing

Finance - Diagnostics company reports net income increased to $130 million

Finance - Drug developer focused on respiratory diseases reports 75% increase in sales

Finance - Drugstore chain reports 0.9% same store sales increase for January 2006

Finance - Endoscopic devices developer reports Q3 06 sales up 18% to $3.33 million over Q3 05

Finance - Exercise monitoring products company intends to become publicly reporting company

Finance - Gastroesophageal reflux disease drug developer completes Series E financing

Finance - Gastrointestinal drug maker reports 10% increase in sales

Finance - Health Management Associates reports 14.9% increase in patient service revenue

Finance - Health Net reports fourth quarter income of $.65 per share

Finance - Healthcare products company reports Q1 2006 earnings of 39 cents per share

Finance - Healthcare products company reports Q4 05 net revenue up 2% to $4.7 billion

Finance - Healthcare real estate company declares quarterly common dividend of $0.38 per share

Finance - Healthcare, drug company reports GAAP net Q4 05 sales of $2.3 billion, up 6% from year ago

Finance - Healthcare, life sciences company reports Q3 2006 revenue increase of 5% to $287.5 million

Finance - Hearing aid company reports full year 2005 net sales up 7%, down 3% in Q4

Finance - Imaging company announces record backlog of $158 million

Finance - Imaging technology company reports Q3 2005 revenue up 31%, net income up 37% over year ago

Finance - Infusion pump maker reports earnings of $0.60 per share

Finance - Innovent invests in Quantum Intech

Finance - Israel-based generic drug company sets pricing of $1.25 billion of convertible debentures

Finance - Kindred Healthcare announces $100 million increase to available credit capacity

Finance - Lilly reports $3.879 billion in sales

Finance - Maker of blood processing systems prices public offering of common stock at $4 per share

Finance - Maker of cardiology instruments announces closing of common stock offering

Finance - MedImmune reports revenues of $1.2 billion

Finance - Medical device company reports revenues of $2.1 million

Finance - Medical device company reports total revenues of $10.3 million for the fourth quarter 2005

Finance - Medical device maker reaffirms prior guidance for 2005

Finance - Medical laser developer posts earnings of $0.12 per share

Finance - Medical products company announces net revenues of $131.9 million

Finance - Medical products distributor reports revenue of $4.82 billion

Finance - Myeloma foundation awards over $8 million in 2005 to Multiple Myeloma Research Consortium

Finance - Mylan Laboratories reports earnings per share of $0.25 for third quarter

Finance - Nanomaterials company shareholders to receive one additional share for each share held

Finance - Natural and organic products company reports record Q2 2005 sales up 10% from year ago

Finance - Neurobiological Technologies receives $1.4 million quarterly royalty payment related to Memantine

Finance - Neuroscience drug maker receives $4.2M from exercise of warrants

Finance - Neuroscience drug maker reports loss of $0.10 per share

Finance - Nutritional products company reports net sales of $455 million for first quarter

Finance - Oncology diagnostics-focused company reports 2005 revenues increased 26% to $68.5 million

Finance - Ophthalmology company reports 10.7% increase in sales

Finance - Oral fluid diagnostics company reports on stock split

Finance - OrthoLogic reports net loss of 7.5 million or $0.20 per share for the fourth quarter

Finance - Pharma company announces Tarceva net sales of $25 million for fourth quarter

Finance - Pharma company announces intention to raise $40 million in new capital

Finance - Pharma company begins trading under symbol NHPI, announces $4.35 million private placement

Finance - Pharma company sales increase 16% in 2005

Finance - Pharma firm focused on Asian markets receives American Stock Exchange notification

Finance - Pharma giant reports 1.1% decline in sales

Finance - Pharmaceutical company reports revenues up 13% for fiscal Q3 2006 over year ago

Finance - Pharmaceutical company sets pricing of initial public offering at $9 per share

Finance - Pharmaceutical division to be separated from parent company

Finance - Pharmaceutical firm files amended report to the U.S. S.E.C.

Finance - Point-of-care technology provider experiences 70% revenue growth in 2005

Finance - Protein therapeutics developer prices initial public offering

Finance - Public offering of common stock priced by RNAi therapeutics company

Finance - Q4 2005 sales of Copaxone up 24% to $323 million, annual sales up 26%, company reports

Finance - QMed, Inc. announces revenue of $22,146,496

Finance - Quotesmith.com reports fourth quarter revenues of $3.9 million

Finance - Respiratory care product maker posts 72% increase in income

Finance - Risperdal Consta maker reports second consecutive profitable quarter

Finance - SBIR grant to be used for study of drug for stroke patients

Finance - Sierra Health reports Q4 2005 net income of $28.3 million, up from $28 million a year ago

Finance - Somanetics reports record net revenues for FY 2005

Finance - Specialty pharma company signs definitive agreement for $65 million private financing

Finance - StanCorp Financial Group reports 17.8% increase in net income per share in Q4 2005

Finance - Surgical device maker posts 10% increase in revenue

Finance - Surgical device maker records 59.3% increase in revenue

Finance - TEDCO awards grant for a smallpox DNA vaccine delivery project

Finance - UCI Medical Affiliates reports revenue up 20% for first quarter of fiscal year 2006

Finance - United American Healthcare reports total revenues for Q2 2006 down from year ago

Finance - Vascular intervention device maker reports earnings per share are up 15%

Finance - Walgreen Co. reports January 2006 sales increase 11.8% over same month 2005

Fitness & Wellness - Adding faith-based component to weight-loss programs enhances success for black women

Fitness & Wellness - DIO is linked to lower spontaneous physical activity and nonexercise activity thermogenesis

Fitness & Wellness - Estrogen replacement therapy was not found to enhance cardiopulmonary response to exercise

Fitness & Wellness - Free sialic acids may be an alternative oxidative stress marker in athletes

Fitness & Wellness - High-dose growth hormone increases glucose production and uptake

Fitness & Wellness - Inequality in recreational resources decreases physical activity, boosts weight gain

Fitness & Wellness - Physician counseling and at-home follow up may improve teen health behaviors

Fitness & Wellness - Reports add new data to fitness & wellness research

Fitness & Wellness - Three independent mechanisms for exercise-associated hyponatremia were identified

Food Allergies - Camel milk found to be potential alternative for children with milk allergies

Food Allergies - FAAN announces availability of free school food allergy programs

Food Safety - EPA registration for germicidal product received by food safety products company

Food Safety - Human clinical trials commenced on citroxin 02 ingestible

Food Safety - Microelectrode-based impedance test provides sensitive Salmonella detection

Food Safety - Report presents biomedical aspects of genetically modified food

Gallstones - Limiting gallstone obstruction to less than 48 hours reduces morbidity

Gastric Cancer - Diagnostic accuracy of gastroscopy to detect gastric tumors evaluated

Gastric Cancer - ELF/TGF-beta signaling inactivated in human gastrointestinal cancer

Gastric Cancer - Glutathione S-transferase M1 gene null genotype linked to gastric cancer risk

Gastric Cancer - High CD40 expression in gastric cancer implicated in liver metastasis

Gastric Cancer - Low intra-tumor variability revealed in gastric cancer

Gastric Cancer - Older age of gastric cancer patients was not a contraindication to surgical treatment

Gastric Cancer - Polo-like kinase 1 depletion inhibits mitosis and apoptosis of gastric cancer cells

Gastric Cancer - Recent studies add new data to gastric cancer research

Gastric Cancer - Sentinel lymph node biopsy using gamma probe in gastric cancer deemed feasible

Gastrinomas - Gastrinomas associated with MEN-1 syndrome

Gastroenterology - Conserved gene regions leave gastric cancers invulnerable to gefitinib

Gastroenterology - Endoscopic therapy optimal for bleeding peptic ulcer with adherent clot

Gastroenterology - Extensive study needed to define severity, type of illness in children with diarrhea

Gastroenterology - Gut protein protects against infection, intestinal breakdown

Gastroenterology - Multislice CT rapidly locates bleeding site in acute GI hemorrhage

Gastroenterology - U.S. FDA grants approval for oral treatment for chronic idiopathic constipation in adults

Gastroesophageal Reflux Disease - Medicare increases reimbursement rate for Plicator procedure

Gastrointestinal Bleeding - Endoscopic treatment can successfully manage bleeding from Dieulafoy's lesions

Gastrointestinal Cancer - Study finds no association between hormone replacement therapy and GI cancer

Gene Research - CST6 modulates genes linked to breast cancer progression

Gene Therapy - BACE1 deletion rescues temporal memory deficits in Alzheimer mouse models

Gene Therapy - Direct targeting of modified tumor cells to Fc gamma RI triggers cytotoxicity

Gene Therapy - Inhibitor of Apoptosis Protein 2 regulates innate immune signaling in Drosophila

Gene Therapy - STAT3 activation is differentially regulated in squamous cell carcinomas

Generic Drugs - Drug maker announces Aventis' preliminary injunction motion denied in Allegra litigation

Generic Drugs - Pharma company announces final U.S. FDA approval for alprazolam extended-release tablets

Generic Drugs - U.S. FDA approves ANDA for generic desmopressin acetate tablets

Genetics & Genomics - Altered molecular genetics and gene expression contribute to kidney tumors

Genetics & Genomics - Ethnic differences may exist in fasting insulin levels for postmenopausal women

Genetics & Genomics - Findings advance knowledge in genetics & genomics research

Genetics & Genomics - Genetic variation detection tool used on mutations associated with therapy in lung cancer

Genetics & Genomics - Genomic diagnostics company plans to meet with U.S. FDA

Genetics & Genomics - Insulin alleles and AIRE gene expression both influence thymus insulin expression

Genetics & Genomics - Key genes identified that enable growth of tuberculosis bacterium

Genetics & Genomics - Link between common deletion polymorphisms can be evaluated in whole-genome association studies

Genetics & Genomics - MT-II brain gene expression is primary candidate for ethanol preference control in mice

Genetics & Genomics - Manganese superoxide dismutase gene polymorphism is linked to stages of albuminuria

Genetics & Genomics - Metformin and oleic acid reduce resistin gene expression in isolated adipocytes

Genetics & Genomics - Nonobese diabetic DeltaY1 animals protected from diabetes but DeltaX mice remain at risk

Genetics & Genomics - RNAi Consortium member introduces lentiviral shRNA gene family set for gene silencing

Genetics & Genomics - Research tools company launches program enabling institution-wide access to shRNAmir libraries

Genetics & Genomics - Review examines sarcomeric proteins and familial hypertrophic cardiomyopathy

Genetics & Genomics - SNAI1, functioning as E-cadherin repressor, is implicated in gastric cancer

Genetics & Genomics - Scientists force viruses to evolve as better delivery vehicles for gene therapy

Genetics & Genomics - Some infants lose RSV strain-specific and group-specific immunity within months of epidemic

Geriatrics - Fat distribution is strongly influenced by genetic factors in young and elderly twins

Germ-Cell Tumors - Follow-up advised for 2 years after first-line treatment of germ-cell tumors

Gestational Diabetes - Effect of obesity on insulin resistance during pregnancy may vary by ethnicity

Glioma - Dihydroartemisinin enhanced radiosensitivity of human glioma cells

Glioma - Temozolomide might benefit glioma patients with deletions of chromosomes 9p/10q

Gonorrhea Vaccines - Peptide shows promise as vaccine candidate against gonorrhea

Gynecological Tumors - Hysterectomy may be best treatment option for placental site trophoblastic tumor

Gynecology - Calcyclin-binding protein may help regulate apoptosis during early pregnancy

Gynecology - Estradiol uses paracrine mechanisms to regulate VEGF receptor in the uterus

Gynecology - Researchers' findings advance gynecology research

HIV-2 Pathogenesis - HIV-2-specific T-cell response does not correlated with CD4 cell counts

HIV/AIDS & Childbearing - HIV status is an important influence on women's choices regarding childbearing

HIV/AIDS Behavioral Medicine - Alcohol consumption linked to high-risk sexual behavior in Gauteng province

HIV/AIDS Behavioral Medicine - Methadone maintenance therapy reduces heroin use and HIV risk behavior

HIV/AIDS Behavioral Medicine - Prevention counseling reduces HIV transmission among uninfected partners

HIV/AIDS Clinical Trials - MedDRA assessed for global events coding in HIV clinical trials

HIV/AIDS Drug Delivery - HIV Tat fusion proteins reduce brain injury following ischemic stroke

HIV/AIDS Drug Development - LC method provides accurate and precise analysis of ritonavir in soft capsules

HIV/AIDS Drug Interaction - Tenofovir drug interactions increase risk for acute renal failure

HIV/AIDS Drug Resistance - Impact of transmitted HIV-1 drug resistance on CD4 cell decline is time dependent

HIV/AIDS Education - Similar stigma attached to AIDS and SARS

HIV/AIDS Genetics - HIV-1 RNA binding protein interacts with Dicer and functions in RNA silencing

HIV/AIDS Genetics & Genomics - Genetic variants in associated host genes may play important role in HIV-1 susceptibility

HIV/AIDS HAART - HIV-1 K103N mutation after HAART withdrawal has little impact on viral fitness

HIV/AIDS HAART - Psychological distress and pain not associated with episodes of detectable viremia

HIV/AIDS HAART - Ritonavir and nelfinavir inhibit a DIDS-sensitive anion current in B-cells

HIV/AIDS HAART - Ritonavir impairs lipoprotein lipase-mediated lipolysis

HIV/AIDS HAART - Three of 8 mutations in ATV/RTV genotypic resistance score predict reduced response

HIV/AIDS Healthcare Costs - Feasible to effectively treat same number of patients at same or lower cost per patient

HIV/AIDS Hypoalphalipoproteinemia - Hypoalphalipoproteinemia in HIV/AIDS likely to be secondary to HIV infection itself

HIV/AIDS Infection - HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood

HIV/AIDS Mortality - Several factors cause HIV/AIDS-related deaths despite mortality rate decline

HIV/AIDS Mutations - HIV-1 subdomain insertions alter polymerase fidelity and mutation frequencies

HIV/AIDS Opportunistic Infection - Oral manifestations occur commonly among HIV-infected children in Romania

HIV/AIDS Palliative Care - HIV/AIDS patients report significant physical and psychological symptoms despite treatment

HIV/AIDS Pathogenesis - CD4 cells induce plasmacytoid dendritic cell activation and maturation in HIV/AIDS

HIV/AIDS Pathogenesis - HIV infection associated with increased NTPDase activity that correlates with CD39+ cells

HIV/AIDS Pathogenesis - HIV-1 Tat is directly involved in AIDS-associated intestinal dysfunction

HIV/AIDS Pathogenesis - LIF induced in initial stages of viral dissemination during primary HIV-1 infection

HIV/AIDS Pathogenesis - Neutralizing antibody responses drive HIV-1 Env evolution during recent infection

HIV/AIDS Pathogenesis - New research in the area of HIV/AIDS pathogenesis detailed

HIV/AIDS Pathogenesis - R362A mutation at the C-terminus of capsid inhibits HIV-1 RNA packaging

HIV/AIDS Pathogenesis - TNF-alpha contributes to induction of an effective immune response against HIV-1

HIV/AIDS Pharmaceutical Research - Extended-release clarithromycin well tolerated and bioequivalent to IR formulation

HIV/AIDS Prevention - Anti-HIV drug has potential to prevent transmission in women

HIV/AIDS Prevention - Call issued for Anglo-French alliance to combat AIDS epidemic

HIV/AIDS Prevention - HIV risks reduced among African American girls when mothers teach about disease

HIV/AIDS Prevention - Journal takes in-depth look at HIV/AIDS over the past 25 years

HIV/AIDS Prevention - Lewis X component in human milk inhibits HIV-1 transfer to CD4+ T lymphocytes

HIV/AIDS Risk Factors - Effectiveness of community outreach to prevent HIV/AIDS in drug users is examined

HIV/AIDS Risk Factors - Report presents results of the Expanded HIV Risk Factor Assessment Project

HIV/AIDS Risk Factors - Study reveals variables affecting HIV risk for African-American women

HIV/AIDS Sociology Research - Thailand community reactions are positive toward persons with HIV/AIDS and their parents

HIV/AIDS Testing - HIV subtype predicts likelihood of early death from AIDS

HIV/AIDS Therapy - Dextrin sulphate 4% appears to be well tolerated in low-risk HIV-negative women

HIV/AIDS Therapy - Sequencing antiretroviral drugs extends the suppression of HIV replication

HIV/AIDS Tobacco Use - Tobacco smoking increases mortality and decreases quality of life in HIV/AIDS

HIV/AIDS Transmission - HIV interacts with target cells in the genital mucosa in multiple ways

HIV/AIDS Transmission - Optimism is growing for acceptance of female condoms for preventing HIV transmission

HIV/AIDS Vaccines - Multigene HIV-1 subtype C DNA vaccine is ready for clinical trials

HIV/AIDS Vaccines - People at risk are most likely to volunteer for HIV vaccine clinical trials

HIV/AIDS Vaccines - Reports advance knowledge in HIV/AIDS vaccines research

HIV/AIDS Vaccines - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines

HIV/AIDS Vaccines - Study compared protocols to optimize production of HIV-1 lentiviral particles

HIV/AIDS-Related Infection - HIV/AIDS impacts skin diseases through multifaceted mechanisms

HIV/AIDS-Tuberculosis Coinfection - No particular MTB or M. avium clones prevail in HIV-infected persons in Japan

HIV/AIDS-Tuberculosis Coinfection - Tuberculosis modestly increases T-cell proliferation in the absence of HIV

Head & Neck Cancer - I-HDR brachytherapy and cervical dissection used to treat head and neck cancer

Head & Neck Cancer - p63 implicated as survival factor for tumor cells of head and neck cancers

Health Promotion - Campaign focuses on improving eye health of aging boomers

Health Promotion - New consumer education campaign focuses on immune system threats

Health Promotion - Recommendations for community interventions for cardiovascular disease are presented

Healthcare Access - Pennsylvania nonprofit organization launches for-profit seniors franchise system

Healthcare Access - Survival rates for black lung cancer patients may be linked to access to care

Healthcare Costs - Administration says Medicare drug coverage will drop overall costs substantially

Healthcare Costs - Generic drug makers speak out against President Bush's budget

Healthcare Costs - Health care costs are similar for heart failure with normal vs. reduced ejection fraction

Healthcare Costs - International differences persist in the cost of acute myocardial infarction

Healthcare Costs - Nurses group protests focus of Bush's healthcare proposals

Healthcare Costs - Pediatricians vote to cut children's healthcare

Healthcare Costs - Survey finds Americans split on national health plan support

Healthcare Coverage - Anthem Blue Cross and Blue Shield Plans expand eligibility for small group businesses

Healthcare Coverage - Anthem Blue Cross and Blue Shield in Nevada launches new options

Healthcare Coverage - Fallon renews contract with AXIA to offer Silver Sneakers fitness program

Healthcare Coverage - Garamendi seeks tighter regulation of PPOs, according to managed care intelligence firm

Healthcare Coverage - Golden Rule enters individual and family market in Georgia

Healthcare Coverage - New York, New Jersey, and Connecticut insurers will not be impacted by WellPoint for a few years

Healthcare Coverage - Reimbursement for minimally invasive procedures often pays surgeons less, study shows

Healthcare Coverage - State of South Carolina selects ActiveHealth Management to provide decision support services

Healthcare Coverage - Studies reveal mandates requiring businesses to provide health coverage are ineffective

Healthcare Coverage - Study shows employees take advantage of wellness benefits

Healthcare Coverage - Survey shows only 26% of adults feel they have saved enough to finance long-term care needs

Healthcare Coverage - U. of Michigan health plan partners to offer online health management tools

Healthcare Coverage - WorkWell Systems introduces functional capacity evaluation tool

Heart Failure - CHF patients with reduced ejection fraction had higher mortality rates

Heart Failure - Forty U.S. centers enrolling heart failure patients in new pacing device safety study

Heart Failure - NT-proBNP testing helps evaluate dyspnea with suspected congestive heart failure

Heart Failure - NT-proBNP testing is valuable for diagnosis, short-term prognosis in dyspneic patients

Heart Failure - Prognostic value of cardiopulmonary exercise testing in heart failure is unaffected by mode of exercise

Heart Failure - Report describes unrecognized syndrome associated with congestive heart failure

Heart Failure - Research reports a validated clinical, biochemical score for diagnosis of acute heart failure

Heart Failure - Review examines drugs for left ventricular remodeling in heart failure

Heart Failure - Studies add new findings to heart failure body of knowledge

Heart Failure - Systole is significantly prolonged, diastole correspondingly shortened in children with HF

Heart Failure - Unique patient profile characterizes HF with preserved systolic function

Heart Failure - Urodilatin may be new therapeutic agent in treatment of decompensated chronic heart failure

Heart Failure - Use of spironolactone in severe CHF patients does not preclude need for beta blockers

Helicobacter Vaccines - Oral H. pylori vaccine is not effective in mice with Fas ligand deficiency

Hematology - Antiphospholipid antibodies can affect point-of-care INR test results

Hematology - Dipyridamole decreases protease-activated receptor and annexin-v binding on platelets

Hematology - Prolyl hydroxylase domain protein 2 is essential for hypoxia-inducible factor regulation

Hematology - Researchers' data advance hematology research

Hemodialysis - Citrate anticoagulation regimen effective in continuous veno-venous hemofiltration

Hemodialysis - Outcome of tunneled femoral dialysis catheter placement elucidated

Hepatic Cancer - Visible light spectroscopy aided standard imaging during RF ablation of liver tumors

Hepatitis A Virus - HAV from clotting factors implicated in infections among hemophiliacs

Hepatitis B Immunization - Lipid microparticles aid in mucosal immunization against hepatitis B

Hepatitis B Virus - Apolipoprotein A-I may be a suitable serum marker in chronic hepatitis B

Hepatitis B Virus - CD58 expression is related to HBV infection severity and degree of liver damage

Hepatitis B Virus - HBV surface antigen is well-tolerated in healthy young adults

Hepatitis B Virus - Natural and lamivudine-induced HBV surface gene mutants characterized

Hepatitis B Virus - Outcome of interferon treatment of chronic hepatitis B determined histologically

Hepatitis B Virus - U.S. FDA approves hepatitis B-specific immune globulin for acute exposure

Hepatitis C Research - Most common HCV type grown in lab for first time

Hepatitis C Therapy - Molecular mechanism discovered that inhibits HCV replication in vitro

Hepatitis C Therapy - Scientists call for hepatitis treatment of young injection drug users

Hepatitis C Therapy - U.S. FDA grants Civacir fast track designation for hepatitis C

Hepatitis C Therapy - U.S. FDA grants fast track designation to investigational oral HCV protease inhibitor

Hepatitis C Virus - CD81 activates naive B lymphocytes

Hepatitis C Virus - Donor age impacts survival in HCV patients receiving liver transplantation

Hepatitis C Virus - Excess weight may protect against early fibrosis after liver transplantation

Hepatitis C Virus - HCV-like particles generated in different cells bind differently to target hepatoma cells

Hepatitis C Virus - Hepatitis B virus Ig-lamivudine combination protects liver allografts

Hepatitis C Virus - Hepatitis C virus core protein relieves transcriptional repression

Hepatitis C Virus - Hepatitis C virus protein 5A regions are not required for genome replication

Hepatitis C Virus - Histological HCV-related abnormalities are coincident with elevated aminotransferase levels

Hepatitis C Virus - Human leukocyte antigens participate in spontaneous clearance of HCV infection

Hepatitis C Virus - Nongenetic determinants operate in spontaneous clearance of HCV in hemophiliacs

Hepatitis Vaccines - HBV CpG-optimized protein and DNA vaccines perform poorly in chimpanzees

Hepatitis Vaccines - Immunoreactive hepatitis B and C epitopes are useful in vaccine development

Hepatocellular Cancer - Early hepatocellular cancer screening advised for HBs antigen-positive Japanese

Hepatocellular Cancer - Growth index used as prognosticator for patients undergoing resection for hepatocellular carcinoma

Hepatocellular Cancer - Inducible nitric oxide synthase and MMP-9 promote liver cancer angiogenesis and progression

Hepatocellular Cancer - Methylation-based molecular margin analysis used in prognosis of HCC patients

Hepatocellular Cancer - Percutaneous laser ablation used to treat hepatocellular cancer

Hepatocellular Cancer - Percutaneous microwave and radiofrequency ablation used to treat hepatocellular cancer

Hepatocellular Cancer - Portal venous pressure measurement helped select optimal resection type for HCC

Herpes Simplex Virus - Marine alga extract suppresses herpes simplex virus in in vivo models

Herpesvirus Infections - Pancreatic duct cell secretion may be protective against herpesvirus infection

Hip Replacement - Findings in hip replacement provide new insights

Hodgkin Disease - Chemotherapy alone used to treat Hodgkin disease in Indian children

Hospice - VITAS hospice care receives certifications to open facility in St. Louis, Missouri

Human Papillomavirus - Cervical mucosal antibodies protect against human papillomavirus 16

Hypertension - Active lifestyle may prevent hypertension in normotensive women

Hypertension - Beta-blockers worsen pulmonary dynamics in portopulmonary hypertension patients

Hypertension - Hypertension-associated nucleotide polymorphism did not diminish treatment efficacy with irbesartan

Hypertension - Hyperuricemia associated with need for antihypertensive therapy

Hypertension - Review examines role of the new beta-blockers in treating cardiovascular disease

Hypertension - Selective ANGII receptor antagonism raises insulin sensitivity and glucose transport rat model

Hypertension - White coat effect is strongly positive in most hypertensive patients

Imaging - Breast imaging report questioned by radiologists

Imaging - Contrast ultrasound perfusion imaging is a novel diagnostic method in peripheral arterial disease

Imaging - Data advance knowledge in imaging research

Imaging - Flat-panel detector volume CT enables high-resolution tooth imaging

Imaging - High-resolution real-time spiral MRI shows promise for guiding coronary interventions

Imaging - Imaging company introduces fetal monitors with new functionality and documentation

Imaging - Imaging company reports ISO certification

Imaging - Imaging reveals effects of bronchodilator and airway clearance treatment in cystic fibrosis

Imaging - Imaging techniques visualize hepatocellular carcinoma in chronic liver disease

Imaging - Michigan health system signs contract to upgrade ophthalmic digital imaging systems

Imaging - Monochromatic synchrotron radiation useful in small animal cortical bone study

Imaging - Myocardial perfusion imaging with ATP is as effective as dipyridamole for diagnosis of CAD

Imaging - New findings in imaging described

Imaging - New findings in the area of imaging described

Imaging - Trial to compare CT colonography with barium enema, optical colonoscopy picks systems

Immunology - New findings in the area of immunology detailed

Incontinence - ActiCuf, alternative to male adult diapers and pads, introduced

Infectious Bronchitis Virus - Infectious bronchitis variant viruses circulate in commercial poultry

Infectious Diseases -  Haemophilus influenzae adherence upregulates ICAM-1 expression

Inflammatory Bowel Disease - Inflammatory bowel disease is treatable using NF-kappaB decoy oligonucleotides

Inflammatory Bowel Disease - Prescription painkillers effective in patients with dormant IBD

Inflammatory Bowel Disease - Review examines complications of biological therapy for inflammatory bowel diseases

Influenza - Copper could help prevent the spread of flu infections

Influenza - Copper industry group says copper could help contain flu

Influenza - Media coverage on flu effective in influencing parents to vaccinate their children

Influenza - Thiovir proven active against various influenza A viruses

Influenza Vaccines - Antibody response to influenza vaccine is low in nursing home residents

Influenza Vaccines - Influenza vaccine effectiveness estimated during an outbreak

Influenza Vaccines - Influenza vaccine with broad spectrum of efficacy urgently needed

Influenza Vaccines - Misconceptions about influenza vaccination exist among healthcare workers

Influenza Vaccines - Modified surfactant stimulates IgA in response to influenza antigen

Influenza Vaccines - Repeated influenza vaccination of healthy children increases influenza risk later in life

Influenza Vaccines - Report presents hospitalization rates for children with viral infections

Influenza Vaccines - Resident physicians have low rates of influenza vaccination

Information Technology - ACS signs outsourcing contract with Johns Hopkins HealthCare

Information Technology - Abovehealth deploys web portal solution to Trinity Health subsidiary

Information Technology - American Family Care selects laboratory information system

Information Technology - Baridata chooses OpSource for on-demand healthcare solution

Information Technology - Bioinformatics group adds technology for computational life sciences research

Information Technology - Bioinformatics software developer awarded contracts with U.S. National Cancer Institute

Information Technology - California managed services organization licenses software for physician communications

Information Technology - Cardiac device maker deploys software to support continuous improvement

Information Technology - Cisco, Intel, and Oracle create consortium to accelerate exchange of medical information

Information Technology - Colorado-based redevelopment authority awards technology company outsourced supplier status

Information Technology - Communications company introduces portable video system for field communications

Information Technology - Company launches online course for lab staff on creating documents to meet ISO standards

Information Technology - Crosslink Orthopaedics selects vendors to deliver real-time inventory visibility

Information Technology - DINMAR links healthcare sites across Champlain region through Oacis EMPI

Information Technology - Eclipsys Knowledge-Based Charting selected by Fairview Health Services

Information Technology - FCG to implement core administrative system for PacificSource

Information Technology - FFF Enterprises uses ERP product-tracking software in electronic drug pedigree system

Information Technology - IT companies launch software for converting data from any source into SEND format

Information Technology - IT company releases upgrades of chemistry lab software tools

Information Technology - Kansas orthopedic hospital moves to paperless system with clinical informatics software

Information Technology - Organizations team to create multistate network to exchange health information

Information Technology - Partners In Care participates in federally funded test of electronic prescribing program

Information Technology - Pervasive Software partners to market compliance software to healthcare clients

Information Technology - Predictive analytics software company announces availability of data mining 30-day trial CD

Information Technology - QCSI announces strategic alliance with Ingenix to integrate products

Information Technology - Revenue cycle web-based software addresses state attorney general's Charity Care proposal

Information Technology - Sanofi-aventis Group signs 3-year software, services contract for sales management system

Information Technology - Software application to automate electronic and paper payment postings launched

Information Technology - Software simplifies connectivity between logic analyzers and oscilloscopes

Information Technology - Sunrise ED Manager activated at New York University Medical Center

Information Technology - Text messaging speeds up treatment for Chlamydia infection

Information Technology - U. of Alabama at Birmingham regional medical campus to implement electronic health record

Information Technology - U.S. biotechnology information center adds new standard submission format for its Trace Archive

Information Technology - Website helps consumers select a physician

Insomnia - Self-help behavioral intervention reported effective in alleviating insomnia symptomatology

Insulin - Biopharma announces improved production method for hESC-derived islet cells

Ischemia - A protein kinase modulates GluR6 Ser phosphorylation during cerebral ischemia

Ischemia - Findings in ischemia provide new insights

Ischemia - Intraluminal hyperoxygenated solution minimizes mitochondrial structural and functional changes

Japanese Encephalitis - European Commission grants Japanese encephalitis vaccine orphan drug status

Kaposi Sarcoma-Associated Herpesvirus - Researchers detail new studies and findings in the area of Kaposi sarcoma-associated herpesvirus

Kidney Cancer - Agency approves new treatment for gastrointestinal and kidney cancer

Kidney Disease - Continuous hemodynamic monitoring may improve volume management for dialysis patients

Kidney Disease - Endothelial function improves for dialysis patients after renal transplantation

Kidney Disease - Healthcare communications company implements kidney disease management project

Kidney Disease - Renal insufficiency remains an independent predictor of adverse outcome after PCI

Laryngeal Cancer - Defining appropriate treatment method early improves survival for advanced laryngeal cancer

Legal Issues - Drugmaker announces dismissal of amended class action complaint relating to Mucotrol

Legal Issues - Molecular diagnostics company, Innogenetics reach agreement and resolve patent litigation

Legal Issues - U.S. court denies OrthoClear's motion to stay proceedings in dental device lawsuit

Legionnaires Disease Outbreaks - Community-wide Legionnaires disease outbreak linked to industrial cooling towers

Leishmaniasis -  Phlebotomus alexandri is probable vector of Leishmania infantum

Leishmaniasis Vaccines - Recent findings illuminate research in leishmaniasis vaccines

Leukemia - Combination of HDAC inhibitors and TRAIL used to treat leukemia

Leukemia - ETS-related gene overexpression predicts a worse outcome in acute myeloid leukemia

Leukemia - Extracellular KIT receptor mutants in leukemia respond to imatinib mesylate

Leukemia - HRQOL concerns over use of dexamethasone in pediatric leukemia addressed

Leukemia - License agreement signed to develop Fodosine for use in oncology

Leukemia - Mutant nucleophosmin predicted favorable prognosis in acute myeloid leukemia

Leukemia - NS-187 proposed as novel agent for imatinib-resistant leukemia

Leukemia - New findings in leukemia described

Leukemia - Nucleophosmin gene mutations predicted favorable prognosis in leukemia

Leukemia - Reports add new data to leukemia research

Leukemia - Research add new data to leukemia body of knowledge

Leukemia - Researchers describe findings in leukemia studies

Leukemia - Studies advance knowledge in leukemia research

Licensing Agreements - License agreement set with Baylor, M.D. Anderson to develop antimicrobial coated implants

Licensing Agreements - Potential migraine compound licensed to BTG

Limb Regeneration - Limb regeneration prospects in humans considered from salamander regeneration perspective

Liposarcoma - p53 gene alterations and reduced p14(ARF) expression linked to poor prognosis in liposarcoma

Liver Cancer - Gastrointestinal complications after radiation therapy for hepatocellular cancer analyzed

Liver Cancer - New findings in the area of liver cancer detailed

Liver Disease - Leptin is not linked to hepatic steatosis, aminotransferases, and serum lipids in children

Liver Disease - Rebio Gen inks extension to technology agreement for hyaluronic acid

Liver Diseases - Angiogenic regulators drive sinusoidal changes after partial liver removal

Liver Diseases - Patients with nonalcoholic fatty liver disease display symptoms of obstructive sleep apnea

Liver Metastasis - Low-dose leucovorin and 5-fluorouracil used to treat liver metastasis

Louse Epidemic - Louse epidemic may have been major factor in French retreat from Russia Vilnius

Lung Cancer - Altered EGFR signaling implicated in genetic susceptibility to lung cancer

Lung Cancer - Causes for racial disparity in surgical treatment of early lung cancer evaluated

Lung Cancer - Extended resection of T4 lung cancer with invasion of the aorta justified

Lung Cancer - Maintenance/consolidation chemotherapy improved survival in lung cancer patients

Lung Cancer - Recent findings in lung cancer described

Lung Cancer - Recent findings in lung cancer provide new insights

Lung Cancer - Researchers provide details of new studies and findings in the area of lung cancer

Lung Cancer - Researchers publish new studies and findings in the area of lung cancer

Lung Cancer - Tumor cell-stromal fibroblast interaction revealed in model of human small-cell lung cancer

Lymphangiogenesis - Embryonic stem cells have the capacity to become lymphatic endothelial cells

Lymphoma - Local tumor invasiveness was most important predictor of survival in lymphoma

MMR Vaccine - Parents in England distrust safety of measles-mumps-rubella vaccine

Macular Degeneration - Macugen receives European regulatory marketing approval as AMD treatment

Macular Degeneration - Phase I study of VEGF Trap shows rapid, substantial and prolonged reductions in retinal thickness

Macular Degeneration - Retinal thickness mapping monitors choroidal neovascularization in treated eyes

Malaria - Climate forecasting systems help predict malaria risk in Africa

Malaria - Malaria-related lactic acidosis safely treated with dichloroacetate

Malaria - Microscopy can improve antimalarial drug targeting in low-transmission areas

Manufacturing Agreements - Sensor maker signs OEM agreement with OSIsoft for PI/RtPM product

Market Analysis - Avian influenza threat shakes doctors' confidence

Market Analysis - China to become a world leader in stem cell research, according report

Market Analysis - FTEs indicate brand challenges rather than dollars spent

Market Analysis - Generics erosion will lead to slow market growth for chronic heart failure treatment

Market Analysis - Market report says personalized medicine and molecular diagnostics to show robust growth

Market Analysis - Report finds every 1% increase in generic dispensing cuts pharmaceutical expenditures by 0.6%

Market Analysis - U.S. has the largest over-the-counter drug market in the world, according to new report

Market Analysis - Weight-loss products market searches for life after low-carb

Marketing - Abanco International expands sales operations

Marketing - Ascend Therapeutics selects sales and marketing services provider to promote EstroGel

Marketing - California foundation launches $1 million campaign to raise healthcare workforce diversity

Marketing - Campaign to take cancer therapy to patients set for launch

Marketing - Maker of genetic analyzer systems seeking North American distribution partners

Marketing - Market report says 2006 launch of cancer vaccine to prevent human papillomavirus expected

Marketing - Promotion "arms race" looks set to continue for the foreseeable future

Marketing - U.S. distribution rights for Medtronic anastomotic vascular surgery device acquired

Measles Vaccines - Combination of measles virus peptides elicit antigen-specific immune response

Measles Vaccines - More sclerosing panencephalitis is prevented by measles vaccine than recognized

Measles Vaccines - Saponins improve immune response to oral plant-made measles vaccine

Medical Devices - Angio-Seal vascular closure device suitable for use in neuroradiological interventions

Medical Devices - Contact lens developer launches aspheric, single-vision, 2-week disposable soft lens

Medical Devices - Disposable solid-state catheter measures swallowing pressure

Medical Devices - Fifth VentrAssist implanted in U.S. feasibility trial

Medical Devices - First patient enrolled in study of implantable cardioverter defibrillators and home monitoring

Medical Devices - High-powered behind-the-ear and open-fit hybrid hearing device introduced

Medical Devices - Immunoprofiling platform with global population coverage launched

Medical Devices - Inferonasal Baerveldt glaucoma drainage implant safe and effective

Medical Devices - MEMS SmartCaps useful for measuring cystic fibrosis treatment adherence

Medical Devices - Mobile trauma database improves point-of-care revenue capture

Medical Devices - Model lung devised for hydraulic testing of total liquid ventilation circuits

Medical Devices - New hypotube launched for catheter manufacturers

Medical Devices - New mass spectrometer products launched

Medical Devices - Novel device enables ab interno approach to trabeculectomy

Medical Devices - Novel microfluidic lab card facilitates rare cancer cell analysis

Medical Devices - Novel transdermal device may have use in alcohol consumption monitoring

Medical Devices - Ocular disease technology company introduces new photocoagulator

Medical Devices - Polyelectrolyte multilayer film coating suitable for oral devices

Medical Devices - Safety information released about older model pacemakers

Medical Devices - Stable polymer nanotubes may have a biotech future

Medical Devices - Study of cardiovascular EKG/ECG monitor completed at Duke University

Medical Devices - U.S. FDA clears combined blood glucose, blood pressure monitor for home use

Medical Devices - U.S. FDA clears two new Troponin-I assays

Medical Devices - U.S. FDA grants clearance for single use cartridge to assess metabolic status

Medical Devices - U.S. FDA grants clearance to market OrthoGlide knee implant

Medical Devices - U.S. FDA issues 510(k) clearance for Fetalgard Lite monitor

Medical Devices - Unilateral cochlear implant performance improved with opposite ear hearing aid

Medicare - ACLA objects to competitive bidding for lab services

Medicare - Cancer organization releases coded guidelines to support U.S. CMS oncology demonstration program

Medicare - Pennsylvania governor seeks to expand comprehensive drug package for seniors

Medicare - Pharmacy services firm questions perceived savings of Medicare drug plan

Medicare - U.S. HHS secretary issues progress report on Medicare Prescription Drug Benefit

Medullary Thyroid Cancer - Prophylactic thyroidectomy advised for C-cell hyperplasia

Melanoma - Biopsy type did not adversely affect locoregional/distant recurrence of melanoma

Melanoma - Data advance knowledge in melanoma research

Melanoma - Immunotherapy company may add additional trial to explore IVIg efficacy for melanoma

Melanoma - Paratumoral epidermal hyperplasia proposed as prognostic factor in melanoma

Melanoma Vaccines - Research add new data to melanoma vaccines body of knowledge

Melanoma Vaccines - Researchers' work adds to melanoma vaccines body of knowledge

Meningioma - Epidemiology of intracranial meningioma reviewed

Meningitis Vaccines - Meningococcal vaccine doses can be reduced with pertussis-containing vaccine

Meningitis Vaccines - Reports describe recent advances in meningitis vaccines research

Menopause - New look at HRT highlights the value of starting soon after menopause

Menopause - Study finds Remifemin reduces menopausal symptoms by 70% in 12 weeks

Mental Health - Depression is not linked to pro-inflammatory cytokine production in CAD patients

Mental Health - Electroconvulsive treatment elevates hippocampal BDNF in rat depression model

Mental Health - Good maternal connection acts as buffer for sexual abuse survivors in marriage

Mental Health - Guidelines are released on pharmacogenetic testing for CYP450 2D6 and CYP4502C19

Mental Health - High-fat diets and impaired glucose regulation decrease cognitive function in diabetics

Mental Health - Long-term poverty affects mental health of children

Mental Health - Lyrica receives positive opinion from CHMP for treatment of generalized anxiety disorder in adults

Mental Health - Men need lifestyle with work and play to prepare for retirement, Harvard publication says

Mental Health - Mental health alliance applauds Amnesty International report

Mental Health - New York medical center geriatric psychiatry program head says depression in elderly widespread

Mental Health - Onset, aggravation of serious illness is suggested as new criterion for depression severity

Mental Health - Research firm finds launch of triple reuptake inhibitors will drive the market for depression

Mental Health - Sequential bilateral rTMS effective for treatment-resistant depression

Mergers & Acquisitions - Acquisition of 25% of BioPad completed, human testing of noninvasive fetal monitor begun

Mergers & Acquisitions - Agreement signed to acquire European drug discovery service company

Mergers & Acquisitions - American Medical Instruments Holdings, Inc. to be acquired for $785M

Mergers & Acquisitions - Angiogenesis-focused biopharmaceutical firm merges with eClic, Inc.

Mergers & Acquisitions - Arcadia Resources acquires respiratory services provider

Mergers & Acquisitions - Chinese healthcare management company accepts Bioceuticals' merger withdrawal memorandum

Mergers & Acquisitions - Company focused on glaucoma acquires Pro Top and Mediking

Mergers & Acquisitions - Drug discovery company signs definitive agreement to acquire Montigen Pharmaceuticals

Mergers & Acquisitions - DrugMax acquires medical office-based oncology pharmacy in central Florida

Mergers & Acquisitions - Emergency medical assistance company set to sell Global Doctor subsidiary

Mergers & Acquisitions - Final results of merger consideration regarding acquisition of Ivax announced

Mergers & Acquisitions - IPC continues expansion through the acquisition of Michigan Hospitalists in Detroit

Mergers & Acquisitions - Innovate will acquire 50% interest in pancreatic chemoresistance inhibitor

Mergers & Acquisitions - Magellan Health Services completes acquisition of National Imaging Associates

Mergers & Acquisitions - Medical device maker acquires Neuroscience Therapy Corp.

Mergers & Acquisitions - Oncology services company to acquire ivpcare

Mergers & Acquisitions - Pathology, clinical reference lab complete merger

Mergers & Acquisitions - Private equity firm acquires majority interest in Bioniche Pharma Group Limited

Mergers & Acquisitions - Purchase of continuing medical education company completed

Mergers & Acquisitions - Rapid testing devices developer announces acquisition of Accu-Stat Diagnostics, Inc.

Mergers & Acquisitions - Rehab and pain management company acquires controlling stake in Amphora, LLC

Mergers & Acquisitions - Research firm acquires Millennium Research Group

Mergers & Acquisitions - United Surgical Partners announces agreement to acquire Surgis, Inc.

Metabolic Disease - 3-Hydroxyglutaric acid may produce the vasculopathy of glutaric aciduria type I

Metabolic Syndrome - Older adults may reduce risk of metabolic syndrome by eating more whole grains

Metabolic Syndrome - Tesaglitazar improves metabolic anomalies related to insulin resistance in nondiabetics

Metaplasia - Expression of small intestinal and colonic phenotypes in intestinal metaplasia examined

Migraine Headaches - U.S. FDA approves new formulation of Imitrex injection

Monoclonal Antibodies - VEGF inhibitors in cancer therapy are focus of review

Multiple Sclerosis - CD45 mutation may increase the risk of multiple sclerosis

Muscular Dystrophy - Biopharma company initiates phase II study of PTC124 in Duchenne muscular dystrophy

Mycobacterium Tuberculosis - Live B. malayi microfilariae pre-exposure alters innate dendritic cell response to MTB

Myeloid Leukemia - Nucleophosmin mutations linked to favorable prognosis in acute myeloid leukemia

Myocardial Infarction - Granulocyte colony-stimulating factor augments cellular cardiomyoplasty in the injured heart

Myocardial Infarction - New findings in myocardial infarction described

Myocardial Infarction - New findings in the area of myocardial infarction described

Myocardial Infarction - One in 14 Irish men having a heart attack drives self to hospital

Myocardial Infarction - ST deviation, troponin elevation are predictors of outcome in unstable angina

Nanotechnology - Framework for risk analysis of nanoparticles is developed

Natural Killer Cells - NK cell-mediated cytotoxicity involves three sequential membrane impairment steps

Natural Products - Curcumin and quercetin improve early outcomes in cadaveric kidney transplant recipients

Natural Products - Hyperforin has a direct effect on mammary tumor angiogenesis

Neisseria Vaccine -  Neisseria lactamica outer membrane vesicles are potential mucosal adjuvants

Neonatal Cardiology - Early surgical closure of ductus arteriosus allows earlier feeding, improved body growth

Neonatal Care - Georgia receives its first March of Dimes NICU Family Support project

Neoplastic Diseases - Intestinal transplantation used to treat intra-abdominal neoplastic disease

Neuroblastoma - New strategies needed for neuroblastoma patients with MYCN-amplified tumors

Neurodegenerative Diseases - Rosiglitazone may help prevent progressive neurodegenerative disease

Neurogenesis - Neural differentiation in chemically defined medium dependent on endogenous FGF signaling

Neurology - Calcium-modulated voltage channels could be the mediators of alcohol tolerance

Neurology - Monocytes foster vascular repair following brain injury

Neurology - New findings in the area of neurology detailed

Neurology - Study confirms that a single memory is processed in three separate areas of brain

Neuroprotection - Neurotrophic agent protects against mitochondrial dysfunction in cortical neurons

Neuroscience - Angiotensin II type 1 receptor blockade supports cerebral cortex angiogenesis

Neuroscience - Caspase-1 activates caspase-6 in human apoptotic neurons

Neuroscience - Recent findings illuminate research in neuroscience

Neuroscience - Recent findings in neuroscience described

Neuroscience - Research in neuroscience provides new insights

Neuroscience - Research paper validates radioiodinated clioquinol as a biomarker for beta-amyloid

Neuroscience - Researchers provide details of new studies and findings in the area of neuroscience

Neuroscience - Researchers report details of new studies and findings in the area of neuroscience

Nocardia Keratitis - Topical moxifloxacin and imipenem successful in complicated case of Nocardia asteroides keratitis

Non-Hodgkin Lymphoma - FDG-PET used in staging and follow-up of children with non-Hodgkin lymphoma

Norovirus Outbreaks - Norovirus gastroenteritis outbreak associated with raw frozen oysters

Nosocomial Infections -  C. difficile-associated disease treatment may include blocking toxin binding to cell surfaces

Nosocomial Infections - New, faster screening test for MRSA developed

Obesity - French may be headed for American levels of obesity, diabetes, and heart disease

Obesity Complications - AII-induced Na+, K+-ATPase activation in proximal tubules may lead to hypertension

Obesity Complications - Cardiac contractile dysfunction in ventricular myocytes found in mouse model

Obesity Complications - Overweight showed better visuospatial speed of processing performance than normal weight

Obesity Diagnostics - ADP can predict variance in visceral adipose tissue volume in children 13 to 14 years old

Obesity Epidemiology - Constant beta3-adrenoceptor stimulation by KTO-7924 improves lipid metabolism in obese rats

Obesity Epidemiology - Study identifies candidate genes for obesity susceptibility

Obesity Epidemiology - Tallness is significantly associated with increased obesity risk in 6-year-old children

Obesity Genetics - Expression of inflammation-related genes is increased in obese Pima Indians

Obesity Pathogenesis - -308A TNF-alpha gene variant is linked to 23% risk of developing obesity and related diseases

Obesity Pathogenesis - AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2alpha in adipocytes

Obesity Pathogenesis - Ataxin-2 is not critical in development or adult survival, but leads to adult-onset obesity

Obesity Pathogenesis - Cdk4 promotes adipogenesis through PPARgamma activation

Obesity Pathogenesis - Common promoter polymorphism in CD14 is linked to TG levels and BMI in nondiabetics

Obesity Pathogenesis - Effect of acute crowding stress on rat brown adipose tissue metabolic function was examined

Obesity Pathogenesis - Human adenoviruses may cause human obesity, studies suggest

Obesity Pathogenesis - IMT in childhood obesity indicates higher cardiovascular disease and diabetes risk

Obesity Pathogenesis - Inadequate sleep is a risk factor for obesity

Obesity Pathogenesis - Leu34Phe mutation leads to hypothalamic bioactive CART deficiency and may lead to obesity

Obesity Pathogenesis - Maternal obesity has a long-term effect on the beta cells of female offspring

Obesity Pathogenesis - Obesity is emerging epidemic in developing countries

Obesity Pathogenesis - Overweight, metabolic, and hormonal adult profile are controlled partly by nursing period

Obesity Pathogenesis - PLA2 activation is linked to generation of placental lipid signals and fetal obesity

Obesity Pathogenesis - PYY[3-36] treatment lowers respiratory quotient and adiposity in diet-induced obese mice

Obesity Pathogenesis - Reports describe recent advances in obesity pathogenesis research

Obesity Pathogenesis - Review discusses adipocytokines, adiponectin, and obesity link

Obesity Pathogenesis - SHP regulates PGC-1alpha expression and energy production in brown adipocytes

Obesity Pathogenesis - Study examines muscle type-dependent responses to insulin in imcTG turnover in obese rats

Obesity Pathogenesis - TSH stimulates IL-6 release from 3T3-L1 adipocytes through cAMP-protein kinase A pathway

Obesity Prevention - Obesity prevention is most critical in childhood and adolescence

Obesity Research -  ACDC and PPAR-gamma genes have differing implications in obesity

Obesity Research - Prolactin release is reduced in premenopausal obese women following weight loss

Obesity Research - Review discusses IGF-I, growth hormone and insulin in white adipose tissue

Obesity Therapy - Higher PYY levels after bariatric surgery improve weight loss and metabolic parameters

Obesity Therapy - Preoperative weight loss in patients undergoing gastric bypass improved outcome

Obesity Therapy - Rosiglitazone restores AMPK signaling in muscle of insulin-resistant obese rats

Obesity Therapy - Sibutramine may help achieve short-term weight loss in morbidly obesity adolescents

Obstetrics - Cesarean rates higher among Puerto Rican women in Puerto Rico than U.S. mainland

Obstetrics - High levels of HtrA1 protein may be biomarker of preeclampsia

Obstetrics - Maternal serum-soluble vascular endothelial growth factor receptor-1 signals preeclampsia

Obstetrics - Medical equipment company licenses placental protein 13, a biomarker for preeclampsia

Obstetrics - Multicenter study to improve obstetrical care quality and risk management announced

Obstetrics - New findings in the area of obstetrics detailed

Obstetrics - New study data support periodontitis link to increased risk of preeclampsia

Obstetrics - Obese women suffer more pregnancy complications, babies at higher birth defect risk

Obstetrics - Omega-3 fatty acids taken by pregnant women have positive impact on child's development

Obstetrics - Overactive bladder in first-time moms diminishes in 3 months after childbirth

Obstetrics - Smoking during pregnancy increases risk of overweight offspring

Oncology - Celecoxib challenges angiogenesis and bone metastasis in tumor models

Oncology - Glycochenodeoxycholate uses oxidative dysfunction to support biliary carcinogenesis

Oncology - Heat shock protein-90 inhibitors can control multiple myeloma

Oncology - Photodynamic therapy shuts down tumor angiogenesis and metastasis in cancer models

Oncology - Research in oncology provides new insights

Oncology - Researchers report details of new studies and findings in the area of oncology

Oncology - Study emphasizes women should see gynecological oncologists for ovarian cancer treatment

Ophthalmology - Hand and automated refractometers produce divergent contact lens assessments

Ophthalmology - Homocysteine may present a risk for age-related macular degeneration

Ophthalmology - New data illuminates research in ophthalmology

Ophthalmology - Phaco/trabeculectomy procedure effective for cataract and glaucoma treatment

Ophthalmology - U.S. FDA approves expanded use of Xibrom to treat post-cataract surgery pain

Ophthalmology - University eye institute, neurology program join to offer ophthalmology diagnostic program

Oral Squamous Cell Cancer - SIP1 expression could be used to prognosticate oral squamous cell carcinomas

Oral Surgery - Flexure deformation predicts outcome of TMJ disk displacement without reduction

Osteoarthritis - Osteoarthritis sufferers may benefit from bone resorption effect of oral salmon calcitonin

Osteoporosis - CHMP recommends first quarterly IV for postmenopausal osteoporosis for approval

Osteoporosis - Pharma companies collaborate to develop and commercialize nasal spray for osteoporosis

Osteoporosis - Premenopausal women with diabetes have more fractures, less bone density, study shows

Osteoporosis - Recent findings illuminate research in osteoporosis

Osteoporosis - Reports add new data to osteoporosis research

Osteoporosis - Researchers describe findings in osteoporosis studies

Osteoporosis - Studies add new findings to osteoporosis body of knowledge

Osteoporosis - Weight-bearing regimen, calcium citrate proven to increase bone mineral density

Osteosarcomas - Cytological differentiation in osteosarcomas examined

Osteosarcomas - Effect of ifosfamide in patients with osteosarcoma of extremity evaluated

Otolaryngology - Product launched to stem nosebleeds

Otorhinolaryngology - Computerized motion analysis superior to subjective assessment of facial synkinesis

Otorhinolaryngology - Nitinol stents effective for treatment of benign proximal tracheal stenosis

Ovarian Cancer - Influence of surgeon experience and hospital volume on ovarian cancer outcome studied

Ovarian Cancer - Loss of COX-2 expression does not contribute to ovarian cancer malignancy

Ovarian Cancer - Oxaliplatin-resistant ovarian carcinoma cells possess unique gene expression

Ovarian Cancer - Research add new data to ovarian cancer body of knowledge

Ovarian Cancer - Researchers' work adds to ovarian cancer body of knowledge

Ovarian Cancer - Suppression of natural killer cell response mediated by the ovarian tumor marker CA125

Pain Management - Brain activity readings show women with low estrogen levels are more sensitive to pain

Pain Management - Cannabis-based Sativex effective for rheumatoid arthritis pain relief

Pain Management - Dominion Diagnostics and "The Legal Side of Pain" announce a joint venture

Pain Management - Postop pain higher, more analgesics needed in laparoscopy patients versus laparotomy patients

Pain Management - Race may influence how disability due to chronic pain effects women

Pain Management - U.S. FDA accepts IND for OxyQD

Pain Management - U.S. FDA grants orphan drug status to high-concentration pain management therapy for PHN

Pancreatic Cancer - Chromosomal aberrations of ampulla of Vater and pancreatic head cancers detected

Pancreatic Cancer - Laparoscopic surgery used to treat pancreatic cancer

Pancreatic Cancer - New research in the area of pancreatic cancer detailed

Pancreatic Insufficiency - First of two phase III studies initiated for EUR-1008M in patients with EPI

Parasitology - Hookworm larvae metalloprotease is involved in tissue migration

Parkinson Disease - Study finds no association between welding and Parkinson disease, movement disorders

Patents - Angioplasty stent patent filed in 1987 issued in 2005

Patents - Company receives second U.S. patent protecting polymer composition of delivery vehicle

Patents - Dental device maker receives U.S. Patent Office action

Patents - Genomics company granted European patent on use of single molecules for DNA analysis

Patents - Ophthalmic company receives patent related to iZon Wavefront-Guided Lens

Patents - Patent allowed for heat shock protein-derived peptides

Patents - Patent application filed for enhanced cholesterol test technology

Patents - Patent covers unique method of isolating adult stem cells

Patents - Patent issued for transmissible spongiform encephalopathies rapid test

Patents - Pharma announces Federal Circuit Court of Appeals remands OxyContin patent case

Patents - Provectus receives fourth pharmaceutical patent for anticancer agents

Patents - Transdermal science company serves patent infringement notice for insulin delivery system

Patents - U.S. patent issued for system to form 3D image of anatomical structures from 2D data scans

Patient Care - Fear of pain associated with medical procedures and illnesses discussed

Pediatric Bone Fracture - Intramedullary nailing effective for unstable forearm fractures in children

Pediatric Cardiology - Catheter ablation in children and adolescents is focus of review

Pediatric Cardiology - Research in pediatric cardiology provides new insights

Pediatric Cardiology - Study determines predictors of survival in congenital diaphragmatic hernia

Pediatric Diagnostics - Prodigy and DPX-L bone densitometers cross-calibrated for children

Pediatric Immunizations - Systematically reviewing qualitative studies complements survey design

Pediatric Obesity - Women's volunteer group launches 2006 childhood obesity initiative "Kids in the Kitchen"

Pediatric Ophthalmology - Lang II stereotest not reliable as pediatric screening for binocular dysfunction

Pediatric Ophthalmology - Trans-sac fixation prevents displacement of silicon lacrimal tube in children

Pediatric Ophthalmology - Unilateral IOLs improve visual acuity development after pediatric cataract removal

Pediatric Otorhinolaryngology - Electronystagmography improves diagnosis of pediatric vestibular disorders

Pediatrics - Children's asthma care improves on state health insurance program

Pediatrics - New moms identify infant gas as stressor for babies and moms

Pediatrics - NightForm infant positioning mattress launched

Pediatrics - Parents of premature infants need to learn about protecting babies against RSV

Peripheral Arterial Disease - Clinical trial underway to test stem cell therapy for peripheral arterial disease

Peripheral Arterial Disease - U.S. FDA fast track status granted for rifalazil in peripheral arterial disease

Personnel - ATP-focused biopharma announces board change

Personnel - Accuro Healthcare Solutions names Patty Reupke senior VP of marketing

Personnel - Alan Ross named senior VP, human capital management, of TriZetto Group, Inc.

Personnel - Argeris 'Jerry' Karabelas named non-executive chair of drug delivery company board

Personnel - Biopharma company elects Jean-Pierre Millon as chairman of the board

Personnel - Biopharmaceutical company names Thomas E. Rathjen vice president of investor relations

Personnel - Biotech company names Neil Roth acting president

Personnel - Biotechnology Council of New Jersey's board of trustees elects Dr. Leslie J. Browne

Personnel - California division of national cancer organization names David Veneziano to top job

Personnel - Cardiovascular device veteran named to board of directors at emergency response firm

Personnel - Chemistry service firm adds two key human resources professionals

Personnel - Clinical research organization adds three experts to global product development services group

Personnel - Company focused on blood viscosity appoints Dr. Ralph E. Holsworth, Jr. to management team

Personnel - Contract research organization names Sara Vidmar executive director for medical devices

Personnel - David B. Nash, MD, and Bruce Morra, PhD, named to InforMedix, Inc. board

Personnel - Dean Lewis appointed Science Center CFO

Personnel - Dr. Nancy Rachman named senior director, safety evaluation and scientific affairs for FPA

Personnel - Drug delivery pharmaceutical company announces workforce reduction

Personnel - Drug delivery systems company appoints Mento A. Soponis chairman and CEO

Personnel - Drug development software company adds staff in product training and strategic consulting services

Personnel - Duncan Higgons joins biopharma as executive vice president, business operations

Personnel - Estracure announces new board appointment

Personnel - Former U.S. Surgeon General Joycelyn Elders joins pharmaceutical company

Personnel - George Pontiakos named president, CEO, North American operations, of nutrition company

Personnel - HealthSouth appoints new head of managed care

Personnel - Healthcare management and technology company announces promotion and senior level appointment

Personnel - Infectious disease-focused pharmaceutical firm appoints chairman of the board

Personnel - Kenneth G. Faulkner named VP, business development, of clinical trials services company

Personnel - Kenneth L. Coleman elected board chairman of computation, data mining software company

Personnel - Kevin O'Grady named head of sales and marketing for medical market communications company

Personnel - Laboratory automation provider appoints Fran Tuttle as president and CEO

Personnel - Liver assist device developer names Richard W. Bank to the board of directors

Personnel - Molecular diagnostics company announces management team changes

Personnel - Nanomaterials developer hires Dr. Jayant Tatake as VP research and development

Personnel - Nasal drug delivery developer forms scientific advisory board

Personnel - New thoracic cancer advisory board formed

Personnel - Ophthalmology firm promotes F. Michael Ball to president

Personnel - Optical products manufacturer CFO Rob Burrows resigns, Kenneth Brizel to serve as acting CFO

Personnel - Patient safety solutions provider names Peter Fisher as vice president of engineering

Personnel - Paul J. Gallagher named senior vice president, enterprise operations, of WellPoint, Inc.

Personnel - PerkinElmer appoints Robert F. Friel president, life and analytical sciences

Personnel - Peter Fellner named non-executive director at vaccines company

Personnel - Pharma company names Mark A. Varney as COO and chief scientific officer

Personnel - Pharma consulting company names Glenn A. Stiegman, III as vice president

Personnel - Pharma product development company appoints Rick A. Bright as VP vaccine research

Personnel - Physical therapy company interim CFO Mark A. Bogovich resigns

Personnel - RNAi therapeutics-focused company appoints Akshay Vaishnaw as VP

Personnel - Radioisotopes company appoints Christopher Wagner as senior VP of sales and marketing

Personnel - Regulatory consulting company hires Nick Nance to provide U.S. FDA related training

Personnel - Respiratory disease-focused drug maker appoints William J. Newell as president

Personnel - Rich Daly returns to pharma company as vice president of marketing and commercial strategy

Personnel - Robert F. Apple named senior VP and chief financial officer at drug delivery firm

Personnel - Sirtris names Garen Bohlin chief operating officer

Personnel - Walgreens names William M. Handal senior vice president of eastern store operations

Pertussis Outbreaks - Early pertussis diagnosis may limit transmission and protect susceptible infants

Pertussis Vaccines - New data illuminates research in pertussis vaccines

Pertussis Vaccines - Researchers report details of new studies and findings in the area of pertussis vaccines

Pharmaceutical Research - Cyclosporin A destroys established angiogenesis in laboratory models

Pharmaceutical Research - Drug delivery company, Donaldson launch jointly developed nanofiber cell culture product

Pharmaceutical Research - Market research firm introduces electronic format of Pharmcor report

Pharmaceutical Research - Market research firm study shows companies spent more than $1 trillion on acquisitions in 2005

Pharmaceutical Research - Phosphosulfomannan angiogenesis inhibitor analogues act variably

Pharmacoeconomics - Study shows taking medications as directed reduces overall healthcare costs

Pharmacology - Mouse pneumonia model requires human epithelial penetration data for extrapolation to human dosing

Philanthropy - Community Hospital of Long Beach announces $432,000 grant from S. Mark Taper Foundation

Philanthropy - Foundation receives grants from The Baxter International Foundation to help with disaster recovery

Physician Certification - American Board of Physician Specialties announces American Board of Disaster Medicine

Pituitary Adenomas - Effect of cAMP-PKA pathway in nonfunctioning pituitary adenomas explored

Pituitary Adenomas - Shh down-regulation implicated in pathogenesis of pituitary adenomas

Pleomorphic Cancer - Caveolin-1 expression in pleomorphic carcinoma correlated with poor prognosis

Pneumococcal Diseases - Epidemiology of childhood pneumococcal disease in U.S. is focus of review

Pneumococcal Vaccines - Study examined characteristics, isotype, and activity of antipneumococcal antibodies

Pneumonia - Pharmacological inhibition of a polymerase enzyme reduces gut inflammation and may limit bacterial translocation

Polycystic Kidney Disease - Scientists find cellular pathway that could lead to drug treatment for polycystic kidney disease

Polycystic Ovary Syndrome - Higher insulin levels/sleep disorders correspond with risk for polycystic ovary syndrome

Polycystic Ovary Syndrome - Hyperinsulinemia may be common trait in metabolic syndrome/polycystic ovary syndrome

Polycystic Ovary Syndrome - Pioglitazone decreases hyperinsulinemia in obese patients with polycystic ovary syndrome

Polycystic Ovary Syndrome - Possible candidate gene is identified for polycystic ovary syndrome

Pompe Disease - Biotech company receives positive opinion for Myozyme from European regulatory committee

Postpartum Depression - Persistent fatigue may be the best way to predict onset of postpartum depression

Premenstrual Dysphoric Disorder - U.S. FDA clarifies status of YAZ PMDD application

Prodrugs - Tumor necrosis factor prodrug restores membrane TNF-like activity

Product Distribution - Air purification company develops distribution in the Pacific Rim

Product Distribution - Patient compliance company named distributor of the SIMpill medication adherence system

Product Licensing - Beverly Hills California physician licenses Prometa physiological protocols

Product Licensing - Delta Chakir to market oral disease risk assessment software to dentists and insurers in Israel

Product Licensing - Hepatitis C virus license agreement signed with Chiron

Product Licensing - Molecular tests company licenses newly discovered coronavirus CoV-NL63 to bioMerieux

Product Licensing - Nutra Pharma to purchase certain medical test-kit patents and licenses from biotech company

Product Licensing - Orthopedic medical technology company secures rights to orthopedic implant material

Product Licensing - Pharma company licenses mitochondrial disease technology from Georgetown University

Product Licensing - Reproductive health organization licenses Biosyn-patented microbicides for the prevention of HIV

Product Licensing - Worldwide rights obtained for cetrorelix in benign prostate hyperplasia

Professional Education - Emergency nurses group selects online learning service to develop geriatric care course

Professional Education - Healthcare leadership project to expand university demonstration project

Prognostics - High tidal volume and positive fluid balance linked to worse outcome in acute lung injury

Prognostics - Low molecular weight heparin may improve prognosis of cancer patients

Prognostics - Presence of ITC in lymph nodes not a prognostic marker for stage I/II colorectal cancer

Prostate Cancer - Biopsy and radical prostatectomy specimen features of prostate cancer compared

Prostate Cancer - Combined androgen blockade with bicalutamide deemed cost-effective in prostate cancer

Prostate Cancer - Data show bicalutamide 150mg plus radiotherapy extends survival in locally advanced prostate cancer

Prostate Cancer - Diindolylmethane downregulates pro-survival pathway in prostate cancer

Prostate Cancer - Examination of antiestrogens as treatment for advanced prostate cancer advocated

Prostate Cancer - Feasibility of continuous infusion of epirubicin in prostate cancer assessed

Prostate Cancer - Ganglion curage in prostate cancer discussed

Prostate Cancer - Gleason scoring varied among pathologists and affected risk in prostate cancer

Prostate Cancer - High-risk black men in U.S. least likely to be screened for prostate cancer

Prostate Cancer - Influence of body size on PSA levels in men with low risk of prostate cancer studied

Prostate Cancer - Innovations in serum and urine markers in prostate cancer described

Prostate Cancer - Ixabepilone was active in patients with hormone-refractory prostate cancer

Prostate Cancer - Leuprolide acetate is available as subcutaneous extended-release injection

Prostate Cancer - Link between biochemical recurrence and interval between prostate biopsy and surgery assessed

Prostate Cancer - Omega-6 fats cause prostate tumors to grow twice as fast

Prostate Cancer - Outcome of patients with fortuitous prostate cancer analyzed

Prostate Cancer - Studies advance knowledge in prostate cancer research

Prostate Cancer - Studies describe new findings in prostate cancer research

Prostate Cancer - Therapeutic effect in prostate cancer assessed by magnetic resonance imaging

Prostate Cancer Vaccines - Provenge slows prostate cancer progression

Protein Production - Multi-product immunoassays are suitable to monitor host cell protein impurities

Proteomics - 2-D protein maps of rat gastrocnemius and soleus muscles constructed

Proteomics - Direct infusion nanoelectrospray QTOF MS enables efficient protein identification

Proteomics - Human chemokine CCL23 may boost angiogenesis by promoting matrix metalloproteinase-2

Proteomics - Nanoliter plugs in microfluidic devices facilitate protein crystallization analysis

Proteomics - Notch ligand Delta-like 4 hinders VEGF-related endothelial cell function

Proteomics - Recent findings in proteomics described

Proteomics - Researchers report details of new studies and findings in the area of proteomics

Pseudomonas Vaccines - Oral Pseudomonas vaccine is safe and immunogenic in healthy adults

Psoriasis - Common T cell receptor alpha-chain variable regions detected in psoriasis

Public Health - Campaign launched raise awareness of childhood cancer in emerging countries

Pulmonary Embolism - U.S. FDA awards conditional IDE for SafeFlo Retrievable Vena Cava Filter

Pulmonary Hypertension - Drugmaker in-licenses pulmonary hypertension compound for development

Quality Assurance - AAPPO calls for development of physician incentives to improve quality within its ranks

Quality Assurance - Healthcare quality organization releases updated standards for Physician Practice Connections

Quality Assurance - Results released from first-ever U.S. national study on cancer care quality

Quality Assurance - U.S. hospitals rated in top 5% have mortality rates 27% lower

Quality of Life - Noninvasive ventilation can improve survival and quality of life in ALS patients

Quality of Life - Standard and blue light-filtering IOLs have similar impact on HRQOL after cataract surgery

Rectal Cancer - Recent studies add new data to rectal cancer research

Rectal Cancer - Tumor-related factors were predictors of oncological outcome for rectal cancer

Renal Cell Cancer - Case of inflammatory myofibroblastic tumor associated with renal cell carcinoma

Renal Cell Cancer - Immunosuppressive acidic protein level used to detect renal cell carcinoma

Renal Disease - First patient enrolled in FREEDOM daily home hemodialysis study

Reproductive Biology - Recombinant human lutropin alfa is not useful in late stimulation assisted reproduction cycles

Reproductive Medicine - Preimplantation cell number may affect birthweight

Respiratory Medicine - Clinical practice guidelines on postinfectious cough are released

Respiratory Medicine - Group rankings shows no city is safe from asthma

Respiratory Medicine - Hydrocortisone therapy improves mechanical ventilator weaning

Respiratory Syncytial Virus - Respiratory syncytial virus outbreak occurred in neonatal intensive care unit

Retinoblastoma - More aggressive bone marrow screening in retinoblastoma patients not recommended

Retrotransposons - Missing steps of jumping-gene replication discovered

Rett Syndrome - Brain derived neurotrophic factor alleviates symptoms of Rett syndrome in mouse model

Rheumatoid Arthritis - Cholesterol lowering drugs shown to have beneficial effect on rheumatoid arthritis cells in vitro

Rheumatoid Arthritis - Pristane induces MHC class II-restricted, arthritogenic T cells

Ricin Vaccines - Positive phase I results of RiVax vaccine announced

Rotavirus - Newly-licensed rotavirus vaccine traveled long road in development

Rotavirus Vaccines - VP8*fragment of the rotavirus spike protein is expressed in yeast

Rubella - Many foreign-born women in Miami are not vaccinated for rubella

SARS Outbreaks - Lack of infection control measures could lead to large-scale hospital SARS outbreaks

SARS Outbreaks - Lessons from SARS outbreak incorporated into U.K. Health Protection Agency plan

SARS Vaccines - Researchers' work adds to SARS vaccines body of knowledge

Schizophrenia - Nicotine downregulates dopamine D2 receptor availability in antipsychotic drug treatment

Schizophrenia - Psychotic-like features may contribute to performance deficits across successive stages of learning

Schizophrenia - Schizophrenic patient's attitude toward drug therapy helps predict intervention compliance

Seizure Disorders - Oxycodone should be used with caution in patients with reduced threshold to seizures

Septicemia Vaccine - Immunization with detoxified endotoxin vaccine protects against sepsis

Sexual & Reproductive Health - Cervical cancer vaccine being altered to treat genital warts

Sexual & Reproductive Health - Endocrinological abnormalities may be underlying cause of recurrent pregnancy loss

Sexual & Reproductive Health - Majority do not believe abstinence programs are effective in preventing or reducing HIV/AIDS

Sexual & Reproductive Health - Male circumcision protects female partners from HIV, other STDs

Sexual & Reproductive Health - Soaring U.K. rates of Chlamydia infection partly due to more sensitive tests

Sexual & Reproductive Health - Vaginal swabs are best when screening for chlamydia and gonorrhea

Skin Cancer - Efficacy, reliability of photodynamic therapy shown for non-melanoma skin cancer

Skin Cancer - Harmful effects of sunlight outweigh benefit of vitamin D production

Sleep Apnea - Acetazolamide improves central sleep apnea in heart failure

Sleep Apnea - Continuous positive airway pressure trial may help diagnose sleep apnea

Sleep Apnea - Obstructive sleep apnea syndrome involves abnormal upper airway sensory input

Sleep Apnea - Researchers' findings advance sleep apnea research

Sleep Disorders - Regulatory update provided on status of NUVIGIL

Smoking Cessation - D-deprenyl, an L-deprenyl isomer, may have abuse potential

Smoking Cessation - Prenatal counseling on smoking cessation helps reduce tobacco use during pregnancy

Sociology Research - Bounded awareness, cognitive blinders can prevent risk recognition in decision making

Soft Tissue Sarcoma - BCOR and/or an ECM-like protein implicated in pathogenesis of PNET sarcomas

Spinal Muscular Atrophy - Licensing agreement aims to boost spinal muscular atrophy drug discovery efforts

Sports Medicine - Extra carbohydrate or protein calories does not improve athlete performance after recovery

Squamous Cell Carcinoma - Expression of p63 in intraepithelial neoplasia and squamous cell cancer analyzed

Squamous Cell Carcinoma - Human beta-defensin-2 participates in proliferation of transformed cervix cells

Squamous Cell Carcinoma - Pre-existing alterations exist in normal epithelium of patients with head and neck cancer

Staffing - Kenexa selects vendor for employment process outsourcing services

Staffing - Recruitment services firm establishes specialized healthcare group

Statins - Findings in statins provide new insights

Statins - New findings in the area of statins described

Statins - Questions regarding benefits of statin therapy are focus of review

Statistics - Multiple logistic regression is being applied to multiple inverse sampling design

Steatohepatitis - Steatohepatitis is associated with liver apoptosis and Bcl-2 expression

Stem Cell Research - FGF6 conditioning may expand immature cell pool by myoblast dedifferentiation

Stem Cell Research - Functional human embryonic stem cell-derived neurons develop in mouse brain

Stem Cell Research - Functional mammary gland generated from a single stem cell

Stem Cell Research - Researchers detail new studies and findings in the area of stem cell

Stem Cell Research - Spermatogonia stem cells and somatic environment in the testis are involved in the aging process

Stem Cell Research - Synovium-derived mesenchymal stem cells have greater chondrogenesis potential than bone marrow-derived mesenchymal stem cells

Stem Cell Research - Testicular side population cell subpopulation lacks Oct4 expression

Stem Cell Transplantation - HHV-6 infection associated with SCT from an allelic-mismatch donor and steroid therapy

Stem Cell Transplantation - HSCT feasible in infants with acute lymphoblastic leukemia

Stem Cell Transplantation - High cure rate of isolated CNS relapse by ASCT in pediatric acute lymphoblastic leukemia

Stem Cell Transplantation - IL-12 associated with reduced relapse without increased incidence of GVHD after AHSCT

Stem Cell Transplantation - Preemptive once-daily ganciclovir safe/effective for CMV viremia after ASCT

Stem Cell Transplantation - Researchers provide details of new studies and findings in the area of stem cell transplantation

Stem Cell Transplantation - Small synthetic cyclic heptapeptide enhances donor bone marrow engraftment

Stem Cell Transplantation - Study examined kinetics of dendritic and T-cell chimerism in stem cell recipients

Stem Cell Transplantation - Transplanted neural stem cells engraft into injured newborn brain

Stem Cell Transplantation - Varicella-zoster virus infection in pediatric post-HSCT may be preceded by transaminitis

Streptococcus Vaccines - Antipolysaccharide Ig responses to S. pneumoniae depend on B-cell receptor signaling

Stroke - Gender differences in attitude may influence decision-making for stroke patients

Stroke - Half of patients with atherothrombotic cerebral infarction have other atherothrombotic sites

Stroke - Low-dose Botox with short electrostimulation improves poststroke spastic drop foot

Stroke - Recent findings illuminate research in stroke

Sudden Infant Death Syndrome - Test results show baby mattress eliminates the heat buildup associated with SIDS

Surgical Technology - Biofragmentable anastomosis ring safe and effective in enterocolic surgery

Surgical Technology - Data advance knowledge in surgical technology research

Surgical Technology - DuraSeal Sealant receives CE Mark for vascular applications

Surgical Technology - Electrothermal bipolar vessel sealing system lowers total thyroidectomy time

Surgical Technology - Endovenous laser treatment eliminates great saphenous vein reflux

Surgical Technology - Novel balloon-type device may facilitate atrial fibrillation surgery

Surgical Technology - Onyx embolization shows promise for endovascular CAVM treatment

Surgical Technology - PTA with selective stent placement in iliac artery had better symptomatic success

Surgical Technology - Subcutaneous gentamycin implant does not prevent infections after loop-ileostomy closure

Surgical Technology - Surgical approach for placement of totally implantable access ports has high failure rate

Surgical Technology - TRS-guided prostate biopsy performed without anesthesia in 90% of study patients

Surgical Technology - Technique for open nerve-sparing radical retropubic prostatectomy described

Surgical Technology - Use of frozen sections in pediatric and adolescent surgical pathology examined

Synovial Sarcomas - Loss of p16(INK4A) expression implicated in development of synovial sarcomas

Synovial Sarcomas - Role of adjuvant therapies to treat grossly-resected synovial sarcoma discussed

T Cells - CD8+ and CD4+ T-cell tolerances can be broken

T Cells - TNF receptor type 2 co-stimulates antigen-driven T cell responses in vivo

T-Cell Lymphoma - CD21 remains most reliable marker of FDCs in angioimmunoblastic T-cell lymphoma

Tendinopathy - NSAIDS may do more harm than good in non-inflammatory tendon conditions

Testicular Cancer - Guidelines on testicular cancer updated

Testicular Tumors - Retroperitoneal lymphadenectomy used to treat non-seminomatous testicular tumors

Thrombocytopenia - Recombinant factor VIIa can control bleeding caused by thrombocytopenia

Thrombosis - Higher levels of whole blood aggregation with anti-alpha(IIb)beta(3) suggest subacute thrombosis

Thyroid Cancer - Galectin-3 expression used as marker for papillary thyroid carcinoma

Thyroid Cancer - U.S. FDA grants fast track designation for Zactima for the treatment of thyroid cancer

Tick-Borne Disease - Research add new data to tick-borne disease body of knowledge

Tissue Engineering - 3D scaffolds compared for osteogenic differentiation potential of dermal fibroblasts

Tissue Engineering - Bioactive scaffold supports fibroblast growth for connective tissue regeneration

Tissue Engineering - Bone chips are suitable for culturing high numbers of differentiated osteoblast-like cells

Tissue Engineering - Collagen composite hydrogels developed for vocal fold lamina propria restoration

Tissue Engineering - Dexamethasone-functionalized gels induce osteogenic encapsulated MSC differentiation

Tissue Engineering - Enzymatic biodegradable multilayered films developed for gene applications

Tissue Engineering - Hepatocyte culture system developed

Tissue Engineering - Hybrid scaffold/cell construct repairs high-load-bearing osteochondral defects

Tissue Engineering - Modified PLGA scaffolds increase osteoblast adhesion and proliferation

Tissue Engineering - Osteoblast-like cells cultured on scaffolds support bone regeneration

Tissue Engineering - Researchers' work adds to tissue engineering body of knowledge

Tissue Engineering - Secrets of the sea yield stronger artificial bone

Tissue Regeneration - Deer antlers may reveal role for stem cells in organ renewal

Tissue Sterilization - Sterilization service selected by Community Tissue Services

Tobacco Use - Healthcare supplier receives U.S. FDA approval to market nicotine lozenges

Tobacco Use - Low level laser therapy for smoking cessation clinic opens in New York City

Tonsillar Carcinoma - P16(INK4A) overexpression used to predict prognosis in tonsillar carcinoma

Tonsillitis - Parents happier with alternative to liquid medications for tonsillectomy

Transplant Medicine - Findings describe new data in transplant medicine research

Transplant Medicine - Findings in transplant medicine provide new insights

Transplant Medicine - HBsAg seropositive status after renal transplantation decreases positive outcomes

Transplant Medicine - Pediatric immune response zones are established for Cylex ImmuKnow assay

Transplant Medicine - Research in transplant medicine provides new insights

Transplant Medicine - Rituximab therapy is effective for cryoglobulinemia in renal transplants

Transplant Medicine - Studies describe new findings in transplant medicine research

Transplant Medicine - Unrelated BMT is feasible for adult T-cell leukemia/lymphoma treatment

Treponema Pallidum - Different classes of superoxide reductases have different structures

Tuberculosis - Medical technology company signs agreement to develop tuberculosis biomarkers

Tuberculosis Infection -  M. tuberculosis infection may protect against allergy in TB endemic area

Tuberculosis Vaccines - Advances in tuberculosis vaccine development summarized

Tuberculosis Vaccines - BCG causes quantitative changes in T-cell subpopulations in infants

Tuberculosis Vaccines - New data illuminates research in tuberculosis vaccines

Tuberculosis Vaccines - Reports add new data to tuberculosis vaccines research

Tuberculosis Vaccines - Review focuses on preclinical testing of new vaccines for tuberculosis

Tumor Staging - Accuracy of tumor staging using various imaging modalities compared

Type 1 Diabetes - Diabetic children have higher osteoprotegerin levels, which may be reduced bone mass marker

Type 1 Diabetes - Lipid peroxidation increases during postprandial phase with glucose and triglyceride changes

Type 1 Diabetes - PTPN22 polymorphism 1858 C/T may be involved in diabetes mellitus pathogenesis in females

Type 2 Diabetes - Elevated visfatin plasma levels are found in type 2 diabetics

Type 2 Diabetes - Increase in prebeta1 HDL is mainly due to higher alpha to prebeta1 HDL conversion rate

Type 2 Diabetes - Increased NT-proBNP plasma levels were found in diabetics with vascular complications

Type 2 Diabetes - Independent 3 year study shows cinnamon can relieve diabetes by lowering blood sugar levels

Type 2 Diabetes - PC-DAC:Exendin-4 to advance into human clinical testing for type 2 diabetes

Type 2 Diabetes - Rosiglitazone plus sulfonylurea drugs improved insulin resistance and beta-cell function

Type 2 Diabetes - Serum insulin, insulin resistance, and beta-cell dysfunction increase GSD risk in females

Type 2 Diabetes - Timing of Humalog Mix25 injections did not impact after meal glucose fluctuations in elderly

Ulcerative Colitis - European Medicines Agency CHMP recommends approval of Remicade for ulcerative colitis

Urology - Reports advance knowledge in urology research

Uterine Cancer - Platinum-based chemotherapy is efficacious in uterine papillary serous carcinoma

Uterine Cancer - Radiation therapy after uterine cancer surgery may have limited impact on survival

Vaccine Delivery - Dendritic cells were targeted using pH-responsive microparticle vaccine carriers

Vaccine Development - Hookworms impair immune response to exogenous antigen during infection

Vaccine Development - Multivalent liposome-based vaccines protect against Neisseria meningitidis

Vaccine Development - Protection induced by BCG vaccine can be augmented using plasmid DNA

Vaccine Development - T cells require TNF-alpha to protect against Histoplasma capsulatum

Vaccine Efficacy - Need exists for vaccination against childhood diseases in Italian paramedical students

Vaccine Safety - Clinicopathological features of persistent nodules at injection sites are presented

Vector Development - Dendrimers in gene delivery are focus of review

Veno-Occlusive Disease - Defibrotide shows success treating severe veno-occlusive disease

Virology - Study compared drug therapy regimens in antiretroviral therapy-naive adults

Virology - Transfer of orf virus from sheep, goats to humans is easily prevented

West Nile Virus - Study subjects had 23 single nucleotide polymorphisms not found in controls

Wound Care - Ag Mesh dressing with silver launched as antimicrobial barrier

Wound Healing - Cytokine integration enhances the angiogenic potential of collagen matrices during wound repair

Zygomycosis - Zygomycosis is an emerging fungal infection

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