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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . April 13th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Bladder Cancer - Bladder cancer mortality in the U.S. influenced by gender and geography

Hypertension - Early blood pressure treatment may postpone hypertension

Lung Cancer - Dana Reeve's death highlights women's lung cancer risks

Obesity Complications - Obesity is an independent risk factor for coronary heart disease mortality

Pott Puffy Tumors - Pott puffy tumor described as rare complication of mastoiditis

Acid Reflux - Rabeprazole may be a valuable step-down therapy for gastroesophageal reflux disease

Acute Myeloid Leukemia - Acute myeloid leukemia outcome not improved after daunorubicin, cytarabine, and thioguanine therapy

Addiction Medicine - Hythiam's PROMETA approved for marketing and reimbursement by CompCare

Addiction Medicine - Stimulant abusers reduce stimulant use with contingency management

Addiction Medicine - Under-age alcohol sales were reduced with compliance checks

Adenovirus Epidemiology - Adenovirus type 3 hexon gene genetic heterogeneity may affect antigenic Ad3 characteristics

Adverse Drug Reaction - BCG vaccination is linked to septic dislocation of the hip

Adverse Drug Reaction - Chiron recalls, withdraws Morupar MMR vaccine from Italian and developing world markets

Adverse Drug Reaction - ICH codes alone are not helpful in evaluating adverse drug reactions

Alcohol Use - Same genes may underlie alcohol and nicotine abuse

Allergy & Immunology - Advances in food allergy research presented at meeting in Miami Beach

Allergy & Immunology - Antibiotic use in infants may double asthma risk

Allergy & Immunology - Autoantibodies to diacyl-phosphatidylethanolamine recognize cytoplasmic domains

Allergy & Immunology - B cell-induced lymphangiogenesis mobilizes dendritic cells

Allergy & Immunology - Interferon-alpha stimulates an anti-viral protein in human hepatocytes

Allergy & Immunology - T cell activation is increased in the absence of the autoimmune regulator

Allergy & Immunology - Verus Pharmaceuticals reports study supporting two doses of epinephrine for anaphylaxis

Allergy & Immunology - Verus donates 5,000 epinephrine auto-injector demonstrators for Anaphylaxis Day at meeting

Alzheimer Disease - Alzheimer study explains death of brain cells

Alzheimer Disease - Medications that lower blood pressure linked to reduced risk of Alzheimer disease

Alzheimer Disease - Myriad Genetics' follow-on study of Flurizan demonstrates continued benefit in Alzheimer disease

Alzheimer Disease - Oregon Health & Science University study aims to prevent Alzheimer by blocking enzyme

Alzheimer Disease - Protein-fibril interaction suggests a novel therapeutic strategy for neurodegenerative diseases

Alzheimer Disease - Report concludes Alzheimer costs will stagger government, family budgets in future

Amyloid Fibrils - Physiological factors affecting beta2 -microglobulin amyloid formation are documented

Amyotrophic Lateral Sclerosis - Amyotrophic lateral sclerosis patients benefit from treatment with non-invasive ventilation

Amyotrophic Lateral Sclerosis - Cognitive impairment appears to be common in ALS patients

Anesthesia - Blood versus crystalloid cardioplegia shows little difference in myocardial oxygen tension

Anesthesia - New research in the area of anesthesia detailed

Anesthesia - Recent findings in anesthesia described

Aneurysms - Large unruptured aneurysms are benefited by treatment

Angiology - 8-iso-PGF2alpha is linked to coronary artery disease in coronary angiography patients

Angiology - Angiogenesis is enhanced by transforming growth factor beta signals

Angiology - Artery stiffness may be predicted by carotid-femoral pulse wave velocity and carotid stiffness

Angiology - Carotid endarterectomy is associated with transient increase in S-100B serum levels

Angiology - Effects of HDL-associated lysosphingolipids operate via Akt->NF-kappa B signaling pathways

Angiology - G protein-dependent regulation of endothelial NO synthase expression is a novel mechanism

Angiology - Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake

Angiology - Homocysteine-induced endothelin-1 release depends on hyperglycemia and reactive oxygen species

Angiology - Lectin-like oxidized LDL receptor-1 is expressed after vascular injury

Angiology - Microenvironmental determinates regulate endothelial cell ephrinB2

Angiology - Neo-aortic regurgitation progresses after arterial switch operation

Angiology - Plasma N-terminal pro-atrial natriuretic peptide is key correlate of vascular endothelial function

Angiology - Reports add new data to angiology research

Angiology - Research in angiology provides new insights

Angiology - Researchers report details of new studies and findings in the area of angiology

Angiology - Wall shear stress implications in atherosclerosis are verified by hemodynamic analysis

Angiotensin - The active losartan metabolite EXP3179 is a partial PPAR-gamma agonist

Anthrax Vaccine - Anthrax mucosal and systemic immunities are induced by nasal immunization

Anti-inflammatory Agents - A plant extract demonstrates anti-inflammatory activity in peripheral blood mononuclear cells

Antibacterial Agents -  Staphylococcus aureus vulnerability to antibiotic treatment may be linked to location in osteomyelitis

Antibacterial Agents - A novel quinolone and sitafloxacin have potent activity against gram-positive pathogens

Antibacterial Agents - Gentamicin-vancomycin-loaded hip spacers inhibited microbial growth for 2 weeks in vitro

Antibacterial Agents - Patients with intraabdominal infections effectively treated with ertapenem

Antimicrobial Agents - A new streptogramin was bactericidal until target strains acquired an erm gene

Antimicrobial Agents - Intra-abdominal infections treated with moxifloxacin monotherapy

Antimicrobial Agents - Lauric acid and gentamicin may produce a bacteriostatic effect

Antimicrobial Agents - Miltefosine and other antileishmanial drugs analyzed for interactions

Antimicrobial Peptides - Antimicrobial peptides trigger pathogen virulence

Antimicrobial Resistance -  Acinetobacter baumannii isolates expressing OXA-58 carbapenemase widely disseminated in ICU

Antimicrobial Resistance -  Acinetobacter species-expressing bla(OXA-58) carbapenemases geographically widespread

Antimicrobial Resistance -  Enterobactefiaceae isolates producing CTX-M ESBL increasing in Austria

Antisense Technology - Antisense oligonucleotide library validates Eg5 as a drug development target

Aortic Injury - Open surgical repair is better for young patients without brain injury

Apoptosis - An adenovirus mutant induces apoptosis and cell-cycle arrest in tumor cells

Apoptosis - Estrogen induction protects cells from mediated apoptosis

Apoptosis - Myc overexpression and ATM inactivation implicated in tumorigenesis

Apoptosis - Polyphenols purified from the aroeira plant induced apoptosis in DU145 cells

Apoptosis - Role of annexin A5 imaging in cancer treatment and surveillance explored

Apoptosis - Schisandrin B enhanced doxorubicin-induced apoptosis of cancer cells

Apoptosis - Studies add new findings to apoptosis body of knowledge

Argon Laser - Argon laser photoablation of conjunctival pigmented nevus

Arthritis - Inflammatory bone destruction requires p38 MAPK activation

Arthritis - Rheumatoid arthritis structural classification differentiates predisposing and protective alleles

Arthroplasty - Arthoplasty with calcar grafting is a reliable treatment option for surgical neck nonunions

Artificial Liver - Serum-free cultured hepatocytes propagated and characterized for downstream applications

Aspergillosis Diagnostics - Invasive aspergillosis and mucormycosis rapidly detected by seminested PCR

Asthma - Asthma risk increased in women with high levels of fat tissue inflammatory protein

Asthma - Higher dose formoterol treatments are not associated with asthma exacerbations

Asthma - Patients tend to view asthma as a temporary health problem

Astrocytomas - Pilomyxoid astrocytoma diagnosed in a patient with neurofibromatosis

Astronomy - Ice volcanoes discovered on Saturn's moon, Enceladus

Astronomy - Kiwi astronomers help find icy 'Super Earth' - Life in space discovery a step closer

Astronomy - New technique provides the first full view of the far side of the sun

Atherosclerosis - Atherosclerosis, MI, and cardiac dysfunction were delayed by hepatic lipase deficiency in model

Atherosclerosis - Findings describe new data in atherosclerosis research

Atherosclerosis - PPARdelta promotes very low-density lipoprotein-derived fatty acid catabolism in macrophage

Atherosclerosis - Reports describe recent advances in atherosclerosis research

Atherosclerosis - Researchers' data advance atherosclerosis research

Atherosclerosis - Studies describe new findings in atherosclerosis research

Autoimmune Disease - Osteopontin-CD44 pathway does not participate in development of autoimmune myocarditis

Avian Disease - Single dose of avian pneumovirus confers long-lasting immunity

Avian Influenza - Baxter study verifies inactivation of H5N1 virus in manufacture of plasma-derived therapies

Avian Influenza - Duck feeding area critical factor in highly pathogenic avian influenza persistence and spread

Avian Influenza - Recombinomics urges release of H5N1 avian influenza sequences from WHO private database

Avian Influenza - U.S. Department of Health orders 1.75 million more courses of anti-viral zanamivir Relenza

Avian Influenza - VHA avian influenza survey shows some hospitals would exhaust supplies in 2 weeks

Awards - Congressman Rush Holt named BIO Legislator of the Year

Awards - EPA names Merck an Energy Star 2006 Partner of the Year

Awards - Frost & Sullivan recognizes Dade Behring for excellence in customer service leadership

Awards - Frost & Sullivan recognizes I-Flow with the 2006 Product Innovation Award for ON-Q PainBuster

Awards - SunLink Health Systems' Missouri Southern Healthcare wins Solucient's 100 Top hospitals award

Awards - University Hospitals of Cleveland earns Solucient's 100 Top Hospital Award

Bioartificial Liver - Bioartificial liver effectively treats fulminant hepatic failure

Biomedical Engineering - Bioengineered grafts generate angiogenesis

Biomedical Engineering - Recent findings in biomedical engineering described

Biomedical Engineering - Skin-derived micro-organs trigger angiogenesis in rabbit models

Bladder Cancer - Invasive bladder cancer outcomes defined using oligonucleotide microarrays

Bladder Cancer - Nonmuscle invasive micropapillary bladder carcinoma treated by early cystectomy

Blood Clotting - Warfarin control of blood clotting was better in patient self-testing and patient self-management

Blood Safety - Blood transfusions linked to increased mortality in patients suffering from cardiac episodes

Bone Structure - Bone marrow density may be enhanced by parathyroid hormone

Brain Cancer - Brain lesions differentiated by proton magnetic resonance spectroscopic imaging

Brain Cancer - Survival of children with primary brain tumors in England and Wales analyzed

Breast Cancer - Adverse breast tumor profile may not be associated with antibiotic use prior to diagnosis

Breast Cancer - Breast cancer ErbB2 signals ignite a proangiogenic cascade

Breast Cancer - Breast cancer cells display alternative splicing

Breast Cancer - Breast cancer in premenopausal women may be associated with prolactin concentrations

Breast Cancer - Breast cancer patients with ATM gene alteration may develop fibrosis after radiotherapy

Breast Cancer - Breast cancer prognosticated by aberrant expression of 5-lipoxygenase-activating protein

Breast Cancer - Breast cancer response to endocrine therapy prognosticated by changes in proliferation

Breast Cancer - Breast cancer therapy trends show favorable physician response to published guidelines

Breast Cancer - Breast cancer therapy utilizes retrovirus-mediated tk gene

Breast Cancer - Breast cancer treatment disparities may exist due to ethnicity and insurance status

Breast Cancer - Breast carcinoma treatment outcomes were analyzed after neoadjuvant chemotherapy

Breast Cancer - Breast symmetry can be early indicator of breast cancer, say experts

Breast Cancer - Concord grape juice may inhibit formation of breast cancer tumors

Breast Cancer - Findings advance knowledge in breast cancer research

Breast Cancer - Human breast carcinoma survival predicted by ADAMTS8 and ADAMTS15 expression

Breast Cancer - Lower breast cancer survival rates among South Asian women reveals need for outreach

Breast Cancer - Mammography rates underscore important role of healthcare providers

Breast Cancer - Omitting axillary dissection after negative sentinel node biopsy is not contraindicated

Breast Cancer - Possible breast cancer therapy believed to be inhibition of Notch signaling

Breast Cancer - Predicting posttraumatic growth in breast cancer survivors discussed

Breast Cancer - Proliferation of breast cancer measured by Ki67 expression

Breast Cancer - Recent findings illuminate research in breast cancer

Breast Cancer - Reports add new data to breast cancer research

Breast Cancer - Reports advance knowledge in breast cancer research

Breast Cancer - Researchers report details of new studies and findings in the area of breast cancer

Breast Cancer - Researchers' work adds to breast cancer body of knowledge

Breast Cancer - Studies add new findings to breast cancer body of knowledge

Breast Cancer - Trastuzumab plus docetaxel or vinorelbine is effective in certain women with breast cancer

Breast Cancer - Value of prognostic factors to predict risk of death in breast cancer patients waned with time

Bulimia - Bulimia patients were helped by an online self-help program

Bulimia - Individualized therapy improved bulimia treatment

Business & Finance - A.P. Pharma posts loss of $0.33 per share, reports APF530 phase III trial update

Business & Finance - Accelr8 announces 2Q results, continued BACcelr8r development

Business & Finance - Clearant reports operating progress and 2005 financial results

Business & Finance - CoTherix reports increasing Ventavis sales, provides Q4 and 2005 results

Business & Finance - Competitive Technologies reports Q2 net loss of $0.6 million

Business & Finance - DOV Pharmaceutical reports fourth quarter net loss of $16.9 million, provides bicifadine update

Business & Finance - Enzo Biochem reports second quarter results, HIV-1 Stealth Vector trial initiated

Business & Finance - Hana Biosciences reports 2005 net loss of $10 million, discusses milestones

Business & Finance - Hollis-Eden Pharmaceuticals announces fourth quarter net loss of $10.4 million

Business & Finance - Hythiam announces fourth-quarter revenues of $370,000

Business & Finance - InfaCare Pharmaceutical Corp. raises $30 million in series A financing

Business & Finance - Inhibitex reports net loss of $9.5M

Business & Finance - Kosan reports Q4 2005 and year-end financial results, announces corporate restructuring

Business Update - AXM Pharma provides financing plan to the American Stock Exchange

Business Update - AdipoGenix achieves third milestone in deal with Johnson & Johnson

Business Update - Aeolus receives milestone payment, equity interest from cardiovascular firm

Business Update - Avera McKennan Hospital nets orthopedic savings

Business Update - Cleveland Clinic establishes Cleveland Clinic Canada

Business Update - DATATRAK's ECG laboratory component of the eClinical Platform selected by Duke business unit

Business Update - Delta Dental selected to administer Texas dental program for 311,000 uninsured

Business Update - Dendrite creates integrated support center for pharmaceutical industry

Business Update - Eksigent expands chromatography column product line

Business Update - Ellex announces rebranding and shifts focus to direct marketing of its ophthalmic lasers

Business Update - Elsevier brings Chinese research to an international audience

Business Update - Endologix announces filing of annual report on Form 10-K

Business Update - First Berlin issues research update with buy rating on Callisto Pharmaceuticals

Business Update - Fischer Imaging reports update on major contracts

Business Update - Fitch affirms Ochsner Clinic Foundation at 'A-', removes Rating Watch

Business Update - Iconix extends toxicogenomics gene expression database to Affymetrix GeneChip platform

Business Update - Illumina expands GoldenGate genotyping portfolio with three content products

Business Update - ImVisioN obtains license to patents covering intralymphatic administration of allergens

Business Update - Imalux signs China distribution agreement

Business Update - Indiana life sciences initiative reports upgrade in S&P rating, cites market strengths

Business Update - Integrated Security Technologies complete acquisition of oral insulin patent application

Business Update - IntraLase launches new generation laser for blade-free Lasik

Business Update - Iron Mountain supplies information management, X-ray archiving services to PinnacleHealth

Business Update - Korean NIH, Affymetrix to collaborate to identify genes associated with critical diseases

Business Update - Kreatech adds biotin labeling kits for Affymetrix Genechip, gene expression analysis

Business Update - Louisiana hospital selects Zix Corporation's HIPAA compliant e-mail encryption services

Business Update - Most laboratories in Ireland adopting Cytyc's Pap test for cervical cancer detection

Business Update - SAI Global urges high safety standards in wake of lifting of 10-year ban on British beef exports

Business Update - Sequenom launches quantitative methylation and gene expression analysis products

Business Update - Signet announces availability of two new monoclonal antibodies for diagnostic research

Business Update - Simulations Plus releases upgraded version of modeling software for drug discovery

Business Update - VITAS hospice care receives state approval to open program in Kansas City, Kansas

Business Update - Vidar introduces new digital radiography systems

Business Update - VistaCare hospice completes Terre Haute, Indiana, survey in Medicare certification process

Business Update - Warnex contracts with AmeriSci Bio-Chem service lab for PCR pathogen testing services

Business Update - WayPoint Biomedical, Global Informatics form joint entity to market card-based EMR system

Business Update - Windber Research Institute extends collaboration with informatics developer InforSense

Business Update - Zone Medical Systems launches upgrades to ultrasound system with sonography technology

COX-2 - Cyclooxygenase-2 pre-mRNA targeted using antisense morpholino oligonucleotides

Cancer Gene Therapy - Bladder cancer growth is inhibited by an adenovirus expressing dual therapeutic genes

Cancer Gene Therapy - Cervical cancer cell death can be induced by E6 siRNA

Cancer Gene Therapy - Enhanced bladder cancer gene therapy involves restoration of viral receptor expression

Cancer Gene Therapy - New research in the area of cancer gene therapy detailed

Cancer Gene Therapy - Ovarian cancer metastasis is inhibited by adeno-associated virus-mediated gene transfer

Cancer Gene Therapy - Prostate cancer radiation therapy is aided by the use of gene therapy

Cancer Gene Therapy - Recent findings in cancer gene therapy described

Cancer Gene Therapy - Recent findings in cancer gene therapy provide new insights

Cancer Gene Therapy - Small interfering RNA-mediated depletion of CD44 v5 reduced tumor cell invasion

Cancer Gene Therapy - Tumor angiogenesis is suppressed by oncolytic replication-competent adenovirus

Cancer Research - High leptin receptor mRNA expression and leptin levels in breast cancer predicts poor outcome

Cancer Research - San Diego State University team creates antibody that inhibits tumors growth

Cancer Research - Synovial sarcoma oncoprotein SYT-SSX1 tumorigenesis requires IGF2

Cancer Risk Factors - Respiratory cancer risks among workers with glutaraldehyde exposure analyzed

Cancer Staging - Nomogram can predict side specific extracapsular extension at radical prostatectomy

Cancer Therapy - African American women are bearing unequal burden of colorectal cancer

Cancer Therapy - Breast cancer angiogenesis yields to bevacizumab

Cancer Therapy - Breast cancer chemotherapy gets a boost from antiangiogenic therapy

Cancer Therapy - Cancer angiogenesis and growth is abated by the thioredoxin-1 inhibitor PX-12

Cancer Therapy - Chemotherapy can be enhanced by molecular targeting of BCL2 and BCLXL proteins

Cancer Therapy - Findings advance knowledge in cancer therapy research

Cancer Therapy - Gene expression may predict chemotherapy responses in colorectal cancer patients

Cancer Therapy - Gold nanosphere technology expanded to create safer, more penetrating cancer treatment

Cancer Therapy - High-dose intravenous vitamin C is safe for cancer patients, study says

Cancer Therapy - Introgen's Advexin demonstrates safety and antitumor activity in esophageal cancer

Cancer Therapy - Molecular signatures predict disease progression and prognosis of high grade brain tumors

Cancer Therapy - Parenteral nutrition is not superior to fluid therapy for oral mucositis

Cancer Therapy - Prostate adenocarcinoma treated with radio/brachytherapy show no late Grade 4 or 5 toxicity

Cancer Therapy - Prostate cancer cell superoxide production and apoptosis is enhanced by p53

Cancer Therapy - Recent findings illuminate research in cancer therapy

Cancer Therapy - Recent findings in cancer therapy described

Cancer Therapy - Research in cancer therapy provides new insights

Cancer Therapy - Researchers describe findings in cancer therapy studies

Cancer Therapy - Researchers provide details of new studies and findings in the area of cancer therapy

Cancer Therapy - Solid tumors submit to CD8 T cell attack

Cancer Therapy - Studies add new findings to cancer therapy body of knowledge

Cancer Therapy - Targeted tumor therapy is achieved using an antisense compound

Cancer Therapy - Treatment of solid tumors by epoetin beta therapy unaffected by chemotherapy

Cancer Vaccines - Findings advance knowledge in cancer vaccines research

Cancer Vaccines - Researchers provide details of new studies and findings in the area of cancer vaccines

Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge

Carcinogenesis - 1,4-butanediol discounted as a carcinogen

Carcinogenesis - Oral cancer development linked to 8-nitroguanine formation in oral leukoplakia

Carcinogenesis - Proteins with whey-acidic-protein (WAP) motifs implicated in carcinogenesis

Cardiac Migraine - Cardiac migraine may be a distinct entity

Cardiac Risk - Dangers of stopping clopidogrel (Plavix) reported for patients with stents, other conditions

Cardiology - ARRIVE II registry demonstrates 2.5% Taxus-related re-intervention rate in complex lesions

Cardiology - Anti-thrombotic medication reduces risk of death for heart attack patients

Cardiology - Arrhythmogenic right ventricular dysplasia histopathology varies with age - in both ventricles

Cardiology - Cardiovascular risk may be mainly associated with waist circumference in Tehranian women

Cardiology - Coronary heart disease deaths in Ireland halved in 15 years

Cardiology - ECG transmission from ambulance to hospital cuts time to treat heart attacks

Cardiology - Estrogen receptor alpha mediates potassium channel stimulation

Cardiology - Findings describe new data in cardiology research

Cardiology - First human implanted with WorldHeart's next-generation rotary VAD

Cardiology - Functional capacity may help stratify women to pharmacologic versus exercise stress testing

Cardiology - GDF15/MIC-1 functions as a protective and antihypertrophic factor

Cardiology - Many high-risk patients do not receive cholesterol-lowering therapies

Cardiology - New findings in cardiology described

Cardiology - New findings in the area of cardiology described

Cardiology - Obesity-related heart disease may be linked to plasma endothelial cell-specific molecule-1

Cardiology - Paramedics may play role in reducing hospital treatment time for heart attack patients

Cardiology - Patients with angina and coronary occlusion display varying levels of angiogenic growth factor

Cardiology - Patients with subclinical hyperthyroidism show longer corrected QT intervals

Cardiology - Postural blood pressure changes and orthostatic hypotension may be traced to arterial stiffness

Cardiology - Progressive myocardial ischemia stalls upon angiogenic induction by VEGF-C

Cardiology - Recent findings illuminate research in cardiology

Cardiology - Recent studies add new data to cardiology research

Cardiology - Refinements and innovations enhance safety, effectiveness of therapies for acute coronary syndromes

Cardiology - Reports advance knowledge in cardiology research

Cardiology - Researchers develop method to identify children and teens at risk for sudden cardiac death

Cardiology - Researchers publish new studies and findings in the area of cardiology

Cardiology - Researchers' findings advance cardiology research

Cardiology - Should heart attack care be more like trauma care?

Cardiology - Vagal excitation is associated with shortening of fibrillatory cycle length in the pulmonary vein

Cardiology - Vascularized extracellular matrix replaces implanted scaffolds in injured myocardium

Cardiomyocytes - Adenylyl cyclase type V deletion reduces LV responsiveness to beta-adrenergic stimulation

Cardiomyocytes - Hypercontractile female hearts exhibit reduced ischemia/reperfusion injury

Cardiomyocytes - Role of cAMP response element binding protein in cardiovascular remodeling is focus of review

Cardiovascular Disease - After adenosine-induced cardiac arrest, changes in hemodynamic variables reversed completely

Cardiovascular Disease - Findings in cardiovascular disease provide new insights

Cardiovascular Disease - For some aortic aneurysms with distal extension, stepwise anastomosis is a secure option

Cardiovascular Disease - ISIS 301012 does not interact with currently marketed lipid-lowering drugs, study says

Cardiovascular Disease - Ischemic heart disease is associated with mental vulnerability as risk factor

Cardiovascular Disease - Managing hyperlipidemia includes new LDL-C targets for persons at high risk

Cardiovascular Disease - NHLBI Working Group on research in adult congenital heart disease issues recommendations

Cardiovascular Disease - Postoperative white blood cell count predicts atrial fibrillation after cardiac surgery

Cardiovascular Disease - Researchers detail new studies and findings in the area of cardiovascular disease

Cardiovascular Disease - Researchers report details of new studies and findings in the area of cardiovascular disease

Cardiovascular Disease - Specialists offer practical steps in prevention and care of cardiovascular disease

Cardiovascular Research - Atrial fibrillation is associated with differential remodeling in myocardium

Cardiovascular Research - Cardiac Science announces new research for assessing risk of cardiovascular death

Cardiovascular Research - Cardiovascular effects of matrix metalloproteinases in murine models provide wealth of data

Cardiovascular Research - Clinical impact of bleeding measured by two classifications was compared in acute coronary syndrome

Cardiovascular Research - Data analysis shows Vytorin significantly reduced LDL cholesterol in comparison group

Cardiovascular Research - Drug-eluting and absorbable stents push interventional frontiers

Cardiovascular Research - Heart attack patients do better with sirolimus-eluting stent than bare-metal stent, study says

Cardiovascular Research - High intensity statin therapy shows promise for inducing regression of coronary atherosclerosis

Cardiovascular Research - In aortic arch repair, deep hypothermia with retrograde cerebral perfusion is safe, effective

Cardiovascular Research - In atherosclerotic lesions of heart disease patients, diverse bacterial signatures were detected

Cardiovascular Research - Inflammatory heart disease, myocardial proteases, and matrix remodeling are focus of review

Cardiovascular Research - Ischemic preconditioning causes biphasic pattern of ST elevation during repeat coronary occlusions

Cardiovascular Research - Nissan Chemical reports NM-702 associated with an increase in patients' peak walking time

Cardiovascular Research - Use of cardiac resynchronization devices during hospital stays linked to better outcomes

Cardiovascular Risk Factors - Coronary heart disease risk is associated with plasma homocysteine thiolactone adducts

Cataract Surgery - New data illuminates research in cataract surgery

Cell Differentiation - Skeletal muscle satellite cell differentiation requires lamin A/C and emerin

Cervical Cancer - Cervical cancer therapy with total laparoscopic radical hysterectomy appears feasible/safe

Cervical Cancer - Recent findings illuminate research in cervical cancer

Cervical Cancer - Smoking may increase risk of squamous cell carcinoma of the cervix

Chemotherapy - Inex licenses three targeted chemotherapy products to Hana Biosciences

Cholangiocarcinoma - Cholangiocarcinoma is treatable with combination virus-radiation therapy

Cholera Toxin - Cholera toxin induces immunomodulator transcriptional responses

Chronic Myelogenous Leukemia - Chronic myelogenous leukemia linked to enhanced expression and activity of DNA polymerase beta

Chronic Obstructive Pulmonary Disease - Compound from Pharmacopeia collaboration shows clinical activity for COPD in phase I trial

Chronic Pain - Elite participates in First Albany Capital's Chronic Pain Conference, discusses opioid therapy

Circovirus Epidemiology - Porcine circovirus type 2 highly prevalent in pigs naturally infected with PEDV

Clinical Trials - Acologix phase II study of AC-100 meets goal of stimulating new dentin formation

Clinical Trials - Alexion updates phase III results for PRIMO-CABG2 study

Clinical Trials - Angiomax monotherapy is superior to heparins plus GP IIb/IIIa combination

Clinical Trials - Arixtra reduced risk of death or recurrent heart attack in patients with acute coronary syndromes

Clinical Trials - Atherosclerotic events are reduced as effectively by angiotensin receptor blockers as ACE inhibitors

Clinical Trials - Avicena reports promising phase II results from Parkinson disease trial

Clinical Trials - Clinical trial shows 96% improvement in pressure ulcer healing among nursing home residents

Clinical Trials - Critical Therapeutics announces decision to discontinue clinical trial of CTI-01

Clinical Trials - Dynogen initiates Phase II Trial of DDP225 for treatment of chronic functional vomiting

Clinical Trials - Eisai reports results from latest Donepezil study in vascular dementia

Clinical Trials - Eli Lilly launches phase 3 trial of targeted oral cancer agent in glioblastoma multiforme

Clinical Trials - Enzo Biochem initiates phase II trial of immunomodulatory compound for Crohn's disease

Clinical Trials - Excellent in-stent restenosis clinical trial results reported for TAXUS Stent System

Clinical Trials - Inflazyme, Helicon initiate phase IIa trial of IPL455,903 in age-associated memory impairment

Clinical Trials - Insert Therapeutics receives U.S. FDA approval for IT-101 phase I clinical trial

Clinical Trials - KeraCure initiates multicenter pivotal study of wound healing pack in diabetic foot ulcers

Clinical Trials - Keryx commences phase 2 multicenter study of perifosine treatment for refractory leukemia

Clinical Trials - Kyowa completes phase 3 studies of anti-Parkinson drug istradefylline, plans to submit NDA

Clinical Trials - Phase 2 efficacy study in patients with acute decompensated heart failure initiated

Clinical Trials - Role of angiotensin II receptor blocker therapy is focus of review

Clinical Trials - Samaritan starts second phase 2 monotherapy trial of oral anti-viral agent in HIV patients

Clinical Trials - Spectrum advances anticancer agent toward registration, plans 2006 phase 3 study start

Clinical Trials - Stem Cell Therapeutics reports positive results of phase 1 trial of therapy for stroke

Clinical Trials - Surface Logix initiates phase 1 trial of gastrointestinal-specific MTP inhibitor

Clinical Trials - Synthetic Blood enrolls first patient in phase 2 traumatic brain injury study

Clinical Trials - Targeted Genetics amends clinical protocol in trial of inflammatory arthritis drug

Clinical Trials - Tenecteplase-facilitated PCI was associated with more major adverse events than PCI alone

Clinical Trials - U.S. FDA grants Cerexa fast track designation for PPI-0903

Clinical Trials - U.S. FDA grants approval to begin phase 3 trial of API in congenital emphysema patients

Clinical Trials - U.S. FDA to consult Scientific Advisory Committee on Navy's proposed 'RESUS' trauma trial

Clinical Trials - University of Wisconsin medical, public health school to study new outpatient asthma procedure

Clinical Trials - Vertex reports p38 MAP kinase inhibitor meets endpoints in rheumatoid arthritis study

Clinical Trials - X-Cell Medical initiates enrollment for clinical trial of estradiol eluting stent

Clostridium Difficile -  Clostridium difficile-associated disease-related treatment risk higher with metronidazole

Collaborations - ActivX Biosciences expands collaboration agreement with Pfizer

Collaborations - Albemarle named as Tamiflu production partner

Collaborations - Argos Therapeutics, Novo Nordisk to develop treatment for systemic autoimmune disorders

Collaborations - AstraZeneca, University of Miami, and Humana collaborate to improve consumer health

Collaborations - Avi BioPharma, Cook Group sign agreement to develop Neugene drugs for vascular diseases

Collaborations - Avian influenza awareness, preparedness training offered

Collaborations - Bayer HealthCare acquires OriGene's TrueClone cDNAs for functional analyses

Collaborations - CombiMatrix Molecular Diagnostics and Array Genomics collaborate to expand internationally

Collaborations - Impac signs group purchasing agreement with Consorta

Collaborations - Infinity signs drug discovery alliance with Novartis in oncology

Collaborations - Invitrogen, NIH Chemical Genomics Center enter chemical genetics collaboration

Collaborations - MedAvant teams with Quest Diagnostics to offer expanded choice for diagnostic testing needs

Collaborations - MedLink International aligns with Premier Funding and Financial Marketing Services

Collaborations - Medeikon and American Cardiovascular Research Institute collaborate on cardiac disease technology

Collaborations - Pharmacopeia and Neurocrine expand drug discovery and development collaboration

Collaborations - Pritzker neuropsychiatric research group collaborates in efforts to identify novel targets

Collaborations - Rockwood's business unit Groupe Novasep collaborates with Roche to distribute Tamiflu

Collaborations - Uniprise and eLoyalty to develop analytical technology for healthcare call centers

Collaborations - Waters Corporation, Bruker BioSciences announce collaboration to combine technologies

Collaborations - sanofi-aventis and Roche ink deal to produce shikimic acid

Colon Cancer - Colon cancer risk may be associated with central adiposity in women

Colon Cancer - Colon cancer targeting of parvoviruses is achieved by insertion in P4 promoter

Colon Cancer - Colon cancer tumor vessels bear significant endoglin expression

Colon Cancer - Physicians warn too few Americans getting screened for colon cancer

Colorectal Cancer - Breast cancer linked to detection of cytokeratin 20-positive cells in blood of patients

Colorectal Cancer - Chemotherapy-induced colorectal cancer cell death inhibited by c-FLIP

Colorectal Cancer - Colorectal cancer angiogenesis is linked to VEGF production

Colorectal Cancer - Colorectal cancer did not show objective response when treated with capecitabine and thalidomide

Colorectal Cancer - Risk of colorectal cancer for individuals with a family history estimated

Colorectal Cancer - Use of DNA pools to identify single nucleotide polymorphisms linked to colorectal cancer validated

Complementary & Alternative Medicine -  Aloe arborescens Miller components show antidiabetic properties in mouse model

Complementary & Alternative Medicine - Healthy eating and lifestyle patterns benefit in prolonging wellness

Complementary & Alternative Medicine - Study shows complementary alternative medicine reduces pain and tension in heart surgery patients

Contraception - Barr confirms additional data is not required for approval of Duramed's Seasonique

Contraception - U.S. FDA approves first oral contraceptive to offer drospirenone in a 24-day, active-pill regimen

Contraceptive Microbicide - HIV infection and fertilization targets exploited for contraceptive microbicide development

Contracts - Medwave's Primo spot blood pressure monitoring product added to Novation purchasing agreement

Contracts - NHD awards Novation contract for dual source imaging products and services

Contrast Media - Deaths attributed to X-ray contrast media

Cord Blood Transplantation - Cord blood cell expansion improved following BM-derived mesenchymal stem cell co-culture

Cord Blood Transplantation - Cord blood readily available for children with lysosomal and peroxisomal storage disease

Coronary Artery Bypass - No relation seen between volume and outcome of off-pump coronary artery bypass

Coronary Artery Disease - Trial shows varied stenting methods can be effective in treating complex artery disease

Cosmetic Surgery - Venous thromboembolic prophylaxis in plastic surgery stressed to reduce risk of blood clots

DNA Research - Pausing during reverse transcription increases the rate of retroviral recombination

DNA Research - Researchers devise way to unravel DNA tangles, offering possibilities for cancer treatment

DNA Research - Single nucleotide polymorphisms are detected for medical diagnosis

DNA Research - Smad3 regulates telomerase reverse transcriptase via growth factor beta

DNA Research - Two-step red-mediated recombination allows DNA manipulation in Escherichia coli

DNA Vaccine - DNA vaccine encoding Der p2 allergen down-regulates STAT6 expression

Dementia - Inhibition of cyclooxygenase (COX-2) may slow the progression of clinical dementia in certain cases

Dental Research - Earlier periodontal treatment leads to lower medical costs

Depression - Depression treatment in youth produces significant improvement

Depression - Gender disparity in depression may not be as prevalent as previously reported

Depression - Gene influences antidepressant response

Depression - Lamivudine and ribavirin regulate serotonin transporter expression

Depression - Link between depression and medication nonadherence should be considered in cardiovascular care

Depression - Maintenance treatment prevents recurrence in older adults with single-episode depressions

Depression - Racial differences in mental health care in diabetics exist among Medicaid patients

Dermatology - Allergan receives U.K. approval for Vistabel for treatment of glabellar lines

Dermatology - Inamed's positive phase III results for Juvederm presented at dermatology meeting

Dermatology - Women dermatologists volunteer to teach about sun safety in Miami, Florida

Developmental Biology - Gene expression of Cox5a, 5b, or 6b1 functions in preimplantation mouse embryos

Developmental Biology - Myocardial wall rotation of the outflow tract is implicated in positioning of great arteries

Developmental Biology - Plant cells black out when eaten by leafworms

Developmental Biology - Xenopus hypaxial myogenesis involves lbx1

Diabetes Care - Quality of diabetes care requires improvement

Diabetes Complications - Aspirin can inhibit platelet aggregation in most patients with diabetes

Diabetes Complications - Diabetic control, disease duration, and onset age predict diabetes complications risk

Diabetes Complications - EDHF-mediated and endothelium-independent relaxations are impaired in diabetic rat arteries

Diabetes Complications - Gangrenous foot development in diabetes mellitus may involve lipoprotein (a) levels

Diabetes Complications - Glucagon-like peptide 1 administration may reduce cardiovascular risk in type 2 diabetes

Diabetes Complications - Glycoxidation of LDL promotes apoptotic pathways and NFkappaB activation in coronary cells

Diabetes Complications - Nai + increase influences ischemia susceptibility in hearts from diabetic mice

Diabetes Complications - Rat neutrophil function and metabolism is altered considerably by diabetes

Diabetes Control - CareSens meter most precise blood glucose meter with bias of less than 5%

Diabetes Control - Endocrinologist-directed intervention aimed at primary care physicians improves diabetes care

Diabetes Control - Glucose homeostasis regulation involves estrogen receptor-alpha

Diabetes Control - Hypoglycemic medication beliefs among type 2 diabetes mediates success rate

Diabetes Control - In primary care setting few patients achieved diabetes control targets

Diabetes Control - Insulin glargine plus insulin lispro improved glycemic control in type 1 diabetes

Diabetes Control - Insulin glargine plus oral hypoglycemic agents provide glycemic control in type 2 diabetes

Diabetes Diagnosis - Genetic tests can be crucial for correct classification of diabetes type

Diabetes Diagnosis - Primary care practices may improve undiagnosed diabetes detection and improve 1-year outcomes

Diabetes Diagnosis - Retinopathy signs plus a family history of diabetes predict subsequent diabetes risk

Diabetes Education - Diabetes education for youth involving puppets allowed them feel in control of the situation

Diabetes Epidemiology - Benefits of diet in Murcia, Spain do not counteract obesity-related risk factors

Diabetes Epidemiology - EC-SOD gene polymorphism is related to insulin resistance and type 2 diabetes risk

Diabetes Epidemiology - IL-18 promoter polymorphisms are linked to type 1 diabetes predisposition

Diabetes Epidemiology - Interleukin-12p40 gene polymorphism did not seem to play role in type 1 diabetes mellitus

Diabetes Epidemiology - Reports describe recent advances in diabetes epidemiology research

Diabetes Epidemiology - Urinary albumin excretion and renal disease related to diabetes are linked to genetics

Diabetes Management - Healthways announces new agreement with Middle Tennessee Medical Center for diabetes care

Diabetes Pathogenesis - Baroreflex gain are progressively reduced with increasing severity of insulin resistance

Diabetes Pathogenesis - Beta-cell GSIS dysfunction may show fetal survival adaptations that predispose to diabetes

Diabetes Pathogenesis - COX2 (PTGS2) inhibitors augment hexose transport rate in insulin- and AMPK alpha-independent way

Diabetes Pathogenesis - Ca2+ overload and high Ca2+ transport are linked to salivary cell impairment in diabetes

Diabetes Pathogenesis - Decrease in PI-3K/AKT1 survival signaling mediates DN-HNF-1alpha-induced apoptosis

Diabetes Pathogenesis - Diabetes only affects nNOS-containing myenteric neurons without heme oxygenase 2

Diabetes Pathogenesis - Findings describe new data in diabetes pathogenesis research

Diabetes Pathogenesis - Glucagon works to induce ERK 1/2 phosphorylation and raise mesangial cell proliferation

Diabetes Pathogenesis - HNF-4 alpha is essential for glucose stimulated insulin secretion by pancreatic beta-cells

Diabetes Pathogenesis - MCH-/- mice are resistant to aging-associated raises in body weight and insulin resistance

Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis described

Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis detailed

Diabetes Pathogenesis - Phosphorylation of JNK in diabetic rat sensory neurons may impair nerve conduction

Diabetes Pathogenesis - RAS and NOS3 polymorphisms do not seem to influence cardiovascular disease in diabetics

Diabetes Pathogenesis - Rapid infancy weight gain in preterms was slightly related to higher insulin levels

Diabetes Pathogenesis - Recent findings in diabetes pathogenesis provide new insights

Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights

Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis

Diabetes Pathogenesis - Smad7 expression in beta cells disrupts TGF-beta signaling and induces reversible diabetes

Diabetes Pathogenesis - Tissue degeneration in hearts could be caused by increased cell-cycle arrest and DNA repair

Diabetes Pathogenesis - Urinary oxidative stress markers may indicate vascular complication risk in type 1 diabetes

Diabetes Therapy -  Salacia oblonga root improves postprandial hyperlipidemia and hepatic steatosis in diabetes

Diabetes Therapy - Behavioral assessment and intervention in pediatric diabetes is reviewed

Diabetes Therapy - Data advance knowledge in diabetes therapy research

Diabetes Therapy - Diabetes mellitus prevalence has increased steadily in Germany to reach 6.45%

Diabetes Therapy - Diabetic nephropathy progression is delayed by probucol

Diabetes Therapy - Duloxetine offers diabetic neuropathy treatment

Diabetes Therapy - Emotional problems in diabetes patients need increased recognition

Diabetes Therapy - Exenatide dose reduced postprandial plasma glucose excursions in type 2 diabetes

Diabetes Therapy - Glycemic control can be achieved with both glargine plus metformin and NPH plus metformin

Diabetes Therapy - Insulin administration route did not alter glucose metabolism

Diabetes Therapy - Insulin aspart was well tolerated and effective during long-term type 1 diabetes treatment

Diabetes Therapy - Insulin release in novel drug delivery system depends on polymer swelling and crosslinking

Diabetes Therapy - Lisinopril plus telmisartan may prevent diabetic nephropathy type 2 diabetes, hypertension

Diabetes Therapy - NCX4016 has protective effect against ischemia-reperfusion injury in diabetic rat hearts

Diabetes Therapy - Okchun-San-C may lower blood glucose level in type 2 diabetic patients

Diabetes Therapy - Pioglitazone raises adiponectin levels and reduces TNF-alpha levels in type 2 diabetics

Diabetes Therapy - Pioglitazone's insulin-sensitizing offers advantage over gliclazide for glycemic control

Diabetes Therapy - Postprandial lipemia in diabetics is restored to normal by insulin sensitization with pioglitazone

Diabetes Therapy - Reports describe recent advances in diabetes therapy research

Diabetes Therapy - Researchers' findings advance diabetes therapy research

Diabetes Therapy - Restenosis in diabetics with coronary lesions was reduced by radiation after stent implant

Diabetes Therapy - Urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats

Diagnostics - 1.5 T compared to 3.0 T superparamagnetic iron oxide-enhanced liver MRI

Diagnostics - A new aptamer assay allows visual detection of minute concentrations of molecules

Diagnostics - Abbott receives U.S. FDA 510K clearance to market blood glucose monitoring system

Diagnostics - Altor BioScience launches reagents to measure disease-specific antigen presentation

Diagnostics - Applied Biosystems' Avian influenza detection kits available in Europe, Asia, and Africa

Diagnostics - Cardiovascular mortality is predicted by ambulatory arterial stiffness index

Diagnostics - Clinical applications of mammary ductoscopy discussed

Diagnostics - Down syndrome screening by targeted ultrasound may result in missed diagnoses

Diagnostics - Findings in diagnostics provide new insights

Diagnostics - Independent Forensics releases semen testing kit

Diagnostics - Medical Services to deliver Dengue Fever rapid test kits to Middle East

Diagnostics - Meridian Bioscience receives U.S. FDA clearance for diagnosistic test for Helicobacter pylori infection

Diagnostics - New findings in the area of diagnostics detailed

Diagnostics - Reports add new data to diagnostics research

Diagnostics - Research in diagnostics provides new insights

Diagnostics - Researchers detail new studies and findings in the area of diagnostics

Diagnostics - Researchers report details of new studies and findings in the area of diagnostics

Diagnostics - Ventria Bioscience launches animal-free plant-derived diagnostic bacterial cell lysis agent

Diagnostics - Welch Allyn, Natus partner to market hearing loss screening device for infants, children

Diet & Nutrition - Aortic valve disease induced by high fat/high carbohydrate diet in C57BL/6J mice

Diet & Nutrition - Appropriate nutrition is an important component of healthy aging

Diet & Nutrition - Data advance knowledge in diet & nutrition research

Diet & Nutrition - Genetic interactions with diet influence the risk of cardiovascular disease

Diet & Nutrition - Ghrelin neutralization ameliorates obesity in diet-induced obese mice

Diet & Nutrition - Jenny Craig partners with Penn State nutrition researcher on Volumetrics Cookbook

Diet & Nutrition - Leptin appears to raise renal sympathetic nerve activity and BP after chronic high-fat diet

Diet & Nutrition - Low-carbohydrate, high-protein diets improve body mass/composition regardless of energy intake

Diet & Nutrition - PPAR alpha mediates effects of high-fat diet on hepatic gene expression

Diet & Nutrition - Postprandial ghrelin levels was lowered more by high-protein meal than by high-carbohydrate meal

Diet & Nutrition - Reports advance knowledge in diet & nutrition research

Diet & Nutrition - Research add new data to diet & nutrition body of knowledge

Diet & Nutrition - Standards of nutritional care in pediatric oncology evaluated

Diet & Nutrition - Studies add new findings to diet & nutrition body of knowledge

Disease Associations - HIV morbidity and mortality is increased in hepatitis C virus co-infection

Disease Associations - HIV/HCV co-infection follow-up is aided by the use of core antigen-based testing

Disease Associations - Increased psychosocial stress is associated with bacterial vaginosis in nonpregnant women

Disease Associations - Lung cancer prognosis is worse in HIV/AIDS than in general population

Diverticulitis - Recurrent diverticulitis is more likely in obese than in asymptomatic individuals

Drug Abuse - Education initiative on new substance abuse treatment comes to Atlanta, other metro areas

Drug Abuse - Memory, speed of thinking get worse over time with marijuana use

Drug Abuse - Phoenix House admissions data shows rise in meth-related teen treatment, tracks national trends

Drug Delivery - Cationic liposomes are promising in drug and gene delivery

Drug Delivery - Endosomes and lysosomes are the receptors for peptide localization

Drug Delivery - Scientists use wireless MicroChips to control drug release over time

Drug Delivery - Transcutol P may improve the ocular drug delivery of hydrophilic compounds

Drug Development - ALS Association funds study in monkeys of drug with potential to treat Lou Gehrig disease

Drug Development - ATP-sensitive potassium channels are potential targets for the treatment of early Parkinson disease

Drug Development - Adenosine kinase is a novel target for protecting tissues against ischemia

Drug Development - Alba Therapeutics reports positive phase Ib results for AT1001 in autoimmune diseases

Drug Development - Alnylam Research on microRNAs featured in journal

Drug Development - Ambrisentan receives U.S. FDA fast track designation for PAH development

Drug Development - AnorMED reports AMD070 is active in HIV patients

Drug Development - Arbios expands indications for SEPET feasibility trial

Drug Development - Australian snakes' venom could provide the next generation of human therapeutic drugs

Drug Development - Avi BioPharma’s Ebola study results highlighted in journal

Drug Development - Company reviews state of structure-guided drug design

Drug Development - Corroles are specifically delivered to tumor cells via noncovalent conjugates

Drug Development - Eurand's AdvaTab Cetirizine meets major development milestone

Drug Development - Glibenclamide in single oral dose does not reduce pain-free or maximal walking distance

Drug Development - Immtech completes U.S. FDA special protocol assessment

Drug Development - Impax receives U.S. FDA non-approvable letter for Vadova

Drug Development - Indevus Pharmaceuticals' IND for Nebido accepted by U.S. FDA

Drug Development - Inhibition of ATPase and helicase activity suggests a drug discovery strategy

Drug Development - Intravenous delivery of plasmid DNA generates antibody

Drug Development - Shire says U.S. FDA moved NDA for ADHD treatment Daytrana to Class I resubmission status

Drug Development - Simplified ecteinascidin-saframycin analogs synthesized

Drug Development - Spectrum files its thirteenth ANDA with U.S. FDA for injectable drug

Drug Development - Stilbenoids of Kobresia nepalensis exhibited DNA topoisomerase II inhibition

Drug Development - Structural basis for antitumor effect of aplyronine A studied

Drug Development - Takeda selects Lexicon Genetics' hypertension target for development in research alliance

Drug Development - Terascale computing can accelerate development of therapies for SARS and Avian Influenza

Drug Development - Topical antifungal agent for onychomycosis demonstrates good safety profile

Drug Development - Tumor endothelial cells respond to epidermal growth factor receptor kinase inhibitors

Drug Development - Wyeth Pharmaceutical's form of antibiotic tigecycline gets 'positive opinion' in Europe

Drug Discovery - CytRx provides 2006 update on RNAi-based drug-discovery programs

Drug Metabolism - Calcein assays may be able to predict pharmacological interaction properties in clinical settings

Drug Metabolism - Interspecies scaling might not appropriately predict metabolism and disposition of S4

Drug Resistance - MET amplification may uncover cancers sensitive to PHA-665752

Drug Resistance - Methicillin-resistant Staphylococcus is linked to in-hospital mortality in cardiac surgical patients

Drug Toxicity - Education on NSAIDs and aspirin-associated toxicity for primary care physicians is warranted

Drug-Resistant Staphylococcus Aureus - Multidrug-resistant CA-MRSA emergent clones are a major public health concern in Australia

Dystonia - Dystonia may be relieved with acupuncture treatment

Ebola Vaccine - A paramyxovirus-vectored vaccine protects against a lethal-dose Ebola virus challenge

Electronic Medical Records - Connecticut Multispecialty Group selects Allscripts TouchWorks Electronic Health Record

Embryogenesis - Foxd3 mediates zebrafish myf5 expression during early somitogenesis

Embryogenesis - Nodal gene expression and signaling is cooperatively and autonomously regulated in Xenopus

Embryonic Stem Cell Research - ESC lines maintained under common culture and cardiomyocyte differentiation conditions

Embryonic Stem Cell Research - Eye-like structure generated from embryonic stem cells

Embryonic Stem Cell Research - Hematopoietic lineages created from embryonic stem cells is ultimate medical goal

Embryonic Stem Cell Research - Hybrid hepatocytes generated by cell fusion from embryoid body cells in injured liver

Embryonic Stem Cell Research - Immortalized keratinocyte lines derived from embryonic stem cells

Embryonic Stem Cell Research - Site-specific embryonic SC integration efficiently generates single-copy transgenic mice

Emergency Care - North Carolina hospital emergency departments score poorly in child-saving drills

Encephalitis - Encephalitis protection is conferred by immunization with recombinant adenovirus

End-of-Life Issues - Advance planning can help family members make decisions at end of life

End-of-Life Issues - Living fully with end-stage heart failure includes attending to four types of tasks

Endocrinology - Fat distribution pattern and coronary risk profile linked to X chromosome

Endocrinology - Foxa2 coactivation promotes liver fatty acid oxidation and triglyceride/VLDL secretion

Endocrinology - Gap junction coupled KATP channel activity plays key role in regulating insulin secretion

Endocrinology - Ghrelin secretion is lower in obese, but responds equally to oral glucose in obese and lean

Endocrinology - Growth hormone determines sexual dimorphism of hepatic cytochrome expression

Endocrinology - Leptin rapidly alters liver triglyceride secretion and lipid oxidative metabolism in vivo

Endocrinology - Rapid Ca2+ uptake by SERCA pump controls insulin secretion amount

Endocrinology - Recombinant human growth hormone affects metabolic parameters and atherosclerotic markers

Endocrinology - Researchers publish new studies and findings in the area of endocrinology

Endometrial Cancer - Endometrial cancer risk may be increased in women with weight gain or weight instability

Endometrial Cancer - Endometrial carcinoma chemoresistance involves placental leucine aminopeptidase

Endometrial Cancer - Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis

Endometriosis - Angiogenesis in endometriosis tissue may surrender to retinoid therapy

Endometriosis - Association of endometriosis to sex steroid polymorphisms is not supported by trials data

Endometriosis - Bufalin holds promise as a treatment for endometriosis

Endometriosis - Endometriosis garners proangiogenic support from neutrophils and macrophages

Environmental Health - Exposure to volcanic mineral associated with increased mesothelioma incidence in Turkey

Environmental Health - Rare volcanic plumes create uncommonly dangerous ash flows

Environmental Health Risk - Atrazine monitoring reveals the effectiveness of Abraxis ELISA method may be limited

Environmental Health Risk - Lung association, ethanol coalition support Iowa college students' tour in E85 vehicle

Enzymology - Valproic acid alters apoptosis signals in endothelial cells

Epidemiology - Booster vaccination effects on disease epidemiology have been modeled

Epidemiology - Researchers convinced satellites are helpful in tracking epidemics

Epilepsy Therapy - Lacosamide phase III data for epilepsy shows positive results for both primary endpoints

Esophageal Cancer - Esophageal carcinoma staged preoperatively with multidetector CT and virtual endoscopy

Esophageal Cancer - Patients with mucosal cancer without lymphatic invasion treated with local tumor resection

Esophageal Cancer - Routine compared to selective EUS-guided FNA for staging of esophageal carcinoma

Esophageal Squamous Cell Carcinoma - Esophageal squamous cell carcinoma predicted MTR A2756G polymorphism

Esophageal Tumors - Hypoxic esophageal tumors responded to radiotherapy with addition of irinotecan

Facilities - INC Research expands European operations

Facilities - Icon enhances Italian operations with new office

Facilities - Japanese biotech company Aqumen opens U.S. operations in Pennsylvania Science Center

Facilities - MUSC Hollings Cancer Center announces affiliation with Carolina Regional Cancer Center

Facilities - Maker of nasal drug delivery devices Kurve Technology moves to new corporate headquarters

Facilities - Quantum Group completes four new community health systems in Florida

Facilities - SmartCare medical centers, Kerr Drug partner to open centers in Carolina drug stores

Facilities - Sutter Health plans $6.6 billion investment in northern California healthcare services

Facilities - WellBound's newest self-care dialysis facility opens in northern California

Feline Calicivirus - Virulent systemic feline calicivirus is an emerging pathogen

Fibromyalgia - Fibromyalgia patients' adherence to exercise may be enhanced by reducing baseline stress

Fibrosis - Fibrosis progression is not abnormal in chronic HCV with occult HBV co-infection

Finance - $16M grant awarded to the Institute for Systems Biology

Finance - A.D.A.M. reports income of $0.75 per share

Finance - Advanced Life Sciences reports loss of $0.15 per share

Finance - Advanced Magnetics prices common stock offering

Finance - Advanced Medical Optics pledges $1M for refractive lenticular science research

Finance - Adventrx records loss of $0.03 per share

Finance - Akorn completes $19.4M private placement of common stock

Finance - American HomePatient reports slight decrease in revenue

Finance - American Stock Exchange lists stock of Medivation

Finance - Applied Imaging closes $1.3M equity financing

Finance - AutoImmune reports loss of $0.01 per share

Finance - Avant Immunotherapeutics reports loss of $0.05 per share

Finance - Avant accelerates receipt of $40M milestone payment for Rotarix

Finance - Axonyx posts net loss of $0.08 per share

Finance - Biolase reports loss of $0.05 per share

Finance - Bradley Pharmaceuticals reports 36% increase in sales

Finance - CRO Life Sciences Research announces $70 million long-term financing, plan to redeem bonds

Finance - CV Therapeutics reports option grants

Finance - Celesio revenue exceeds EUR 20 billion for first time

Finance - Cell Genesys secures $75 million Committed Equity Financing Facility

Finance - Corautus Genetics Inc. announces pricing of equity offering

Finance - Corcept Therapeutics reports Q4 2005 net loss of $5.2 million

Finance - Cortex reports fourth quarter and year-end operating results

Finance - Cypress Bioscience, Inc. announces net losses in fourth quarter and fiscal year-end results

Finance - DeCODE genetics reports 2005 revenues of $44 million, up from $42.1 million for 2004

Finance - Dendreon reports fourth quarter and year-end results, revenue drops

Finance - Depomed reports significant increase in 2005 revenue

Finance - Dynavax reports fourth-quarter and year-end results close to previous year

Finance - EDAP TMS S.A. reports strong growth in fourth-quarter and year-end results

Finance - EDiets.com reports Q4 2005 revenues of $12.1 million, up 8.5% from a year ago

Finance - Egalet a/s secures US$27.6 million via financing co-led by Atlas Venture and Index Ventures

Finance - Elite announces closing of $10,000,000 private placement

Finance - Emisphere Technologies, Inc. reduces year-end net loss, increases revenue

Finance - EpiCept releases first financial report since merger with Maxim Pharmaceuticals

Finance - First Horizon Pharmaceutical Corporation commences exchange offer

Finance - GPC Biotech reports 33% increase in revenues for fiscal year

Finance - HealthSouth completes recapitalization transactions, prepayment of existing indebtedness

Finance - HealthSpring, Inc., reports 43% increase in revenues for 2005

Finance - Helicos BioSciences announces $40 million funding round

Finance - Helix BioMedix raises $2.6 million in private placement

Finance - Ibex reports quarterly revenue is up 22%

Finance - Icagen reports loss of $5.3M

Finance - Idenix Pharmaceuticals posts loss of $0.27 per share

Finance - Ikonisys raises $10M in series D financing

Finance - Insmed announces proposed public offering of common stock

Finance - Insmed completes $46 million public offering

Finance - Institute for the Study of Aging, Elan announce winners of Alzheimer disease program

Finance - Interleukin releases Q4 and full-year results; net loss of $6.6 million reported for year

Finance - Inverness reports Q4 2005 net revenues of $121.4 million, up from $97.1 million in Q4 2004

Finance - Iomai receives second payment of $2.9 million NIH grant for pandemic flu vaccine research

Finance - Iris International reports 44% increase in revenue

Finance - Isis reports 41% decrease in 2005 proforma loss from operations compared to 2004

Finance - Johnson & Johnson announces board approval of stock repurchase program

Finance - Kaiser Permanente Colorado donates external automated defibrillators to Denver Zoo

Finance - Keryx reports 2005 increase in cash, other assets spurred by common stock offering

Finance - La Jolla reports Q4 2005 net loss of $6 million compared to $11 million a year ago

Finance - Larry C. Glasscock, WellPoint chairman, president, CEO, establishes 10b5-1 equity plan

Finance - LifeCell reports Q4 2005 product revenues of $27 million, up 69% from Q4 2004

Finance - Longs Drug Stores reports preliminary February 2006 4-week revenues of $387.7 million

Finance - Matria Healthcare reaffirms 2006 revenue estimates to be between $370 to $380 million

Finance - Medical device company TransMedics, Inc. raises $29.75 million in series C funding

Finance - Medifast announces revenue of $40.1 million for 2005

Finance - Mera Pharmaceuticals announces first quarter revenue of $152,394

Finance - Metropolitan Health Networks announces revenue for 2005 increased 16% to $183.8 million

Finance - National HealthCare Corporation reports 19.5% increase in net income

Finance - New River Pharmaceuticals realizes net loss of 29.9 million for fiscal year

Finance - Nobel Biocare donates CDN$5 million to Canadian university to establish oral health center

Finance - NovaDel reports second fiscal quarter net loss of $2.8 million

Finance - Pacific Biometrics Inc. completes $3.8 million financing

Finance - Peregrine Pharmaceuticals reports net loss of $3.1 million in third quarter

Finance - Pharmos Corporation reports 2005 fourth quarter net loss of $3 million

Finance - Point Therapeutics reports a net loss of $5,899,000 for fourth quarter

Finance - Polypore announces fourth quarter net sales of $101.6 million

Finance - Primedex Health Systems announces funding of $161 million senior secured credit facility

Finance - Pro-Pharmaceuticals reports fourth quarter net loss of $1,749,000

Finance - Progenics Pharmaceuticals reports fourth quarter revenues were $2 million

Finance - QuadraMed reports net loss of $3.9 million for 2005

Finance - Reliant Technologies secures $22 million in venture funding

Finance - Renal Care Group announces diluted net income per share of $0.52 for fourth quarter

Finance - Somanetics reports Q1 2006 $5.8 million net revenues, up 43% from $4 million in Q1 2005

Finance - Southern Research Institute receives $1.4 million grant to develop anti-viral drug screening tools

Finance - Spectrum reports 2005 net loss of $18.6 million, compared to $12.3 million in 2004

Finance - StemCells reports Q4 2005 net loss of $4,328,000 compared to $4,919,000 for Q4 2004

Finance - Synergetics USA reports record revenue, net profits in Q2 of fiscal 2006

Finance - Targeted Genetics completes $5 million public offering of common stock

Finance - Titan Pharmaceuticals to raise $10 million in registered direct offering of common stock

Finance - Transgenomic reports plans to sell or close, liquidate nucleic acids business

Finance - Unigene enters agreement to sell $13 million in equity securities to institutional investor

Finance - Unigene reports revenue for 2005 of $14,276,000 compared to $8,400,000 a year ago

Finance - Valera reports 2005 net revenues of $26.8 million driven by prostate cancer treatment

Finance - ViroPharma eliminates long-term debt by redeeming remaining $79 million in notes

Finance - WellCare Health Plans, Inc. prices public offering at $39.56 per share

Finance - XOMA reports total 2005 revenues of $18.7 million, up from $3.7 million in 2004

Finance - Xenogen reports record 2005 revenue of $12 million, a 24% increase over Q4 2004

Fitness & Wellness - Commercial abdominal exercise machines demonstrate mixed results and some may contribute to low back pain

Fitness & Wellness - Exercise and diet normalize serum aminotransferase levels in NASH patients

Fitness & Wellness - Exercise can lead to improved functional fitness even among elderly sedentary individuals

Fitness & Wellness - Exercise raises VEGF receptor levels in study volunteers

Fitness & Wellness - Minority and low socioeconomic groups require separate health-related fitness interventions

Fitness & Wellness - Quick Fit Products announces release of exercise DVD tailored to inactive adults

Fitness & Wellness - Understanding aging process is important for protecting and preserving health

Gastric Cancer - Clinicopathological properties of poorly differentiated adenocarcinoma of the stomach described

Gastric Cancer - Disseminated peritoneal scirrhous gastric cancer is responsive to gene-drug therapy

Gastric Cancer - Gastric cancer progression is driven by protease-activated receptor-2

Gastric Cancer - Reports advance knowledge in gastric cancer research

Gastroenterology - Findings advance knowledge in gastroenterology research

Gastrointestinal Cancer - Analysis of cancer prevention strategies for gastrointestinal cancer conducted

Gene Research - Anemone genes reveal versatile building blocks for body plans

Gene Research - Cancer pathogenesis involves small noncoding microRNA

Gene Research - Drug that switches on genes improves myelodysplastic syndrome treatment

Gene Research - Gene linked to violent behavior appears to weaken impulse control circuits in the brain

Gene Research - Researchers transfer specific DNA sequences into the genome of strawberry

Gene Therapy - Cationic gene delivery polymer has been synthesized and characterized

Gene Therapy - Uronic acid functionalized copolymers can be synthetic gene carriers

Gene Therapy - Viral vectors activate endothelial cell signal transduction

Gene Transfer - LYVE-1 cDNA delivery creates blocking antibodies

Generic Drugs - Immtech announces DB289's to be named pafuramidine maleate

Generic Drugs - U.S. FDA approves ANDA for generic mometasone furoate topical solution USP, 0.1%

Genetic Analysis - Combined fast extraction, amplification and analysis of genes holds diagnostic potential

Genetic Research - Compendia Bioscience obtains exclusive rights to commercialize Oncomine

Genetic Research - Roles of FHIT and WWOX fragile genes in cancer discussed

Genetics & Genomics - EGene's genetic analysis technology used to find genotyping strategy in Alzheimer disease

Genetics & Genomics - GSTT1 gene may contribute to type 2 diabetes mellitus development

Genetics & Genomics - GenOway contracts with Italy-based oncology institutes for gene-modified mouse models

Genetics & Genomics - Genetic mutations associated with azathioprine toxicity do not predict hepatoxicity

Genetics & Genomics - Influence of matrix metalloproteinase genotype on cardiovascular disease is focus of review

Genetics & Genomics - More evidence mammals, fruit flies share make-up on function of biological clocks

Genetics & Genomics - Mycobacterial vaccination and infection induces transcriptional responses

Genetics & Genomics - New findings in the area of genetics & genomics described

Genetics & Genomics - Reports describe recent advances in genetics & genomics research

Genetics & Genomics - Study results on ChondroGene's blood-based molecular diagnostics tests published in paper

Geriatrics - Cardiovascular gene expression shifts with advancing age

Germ Cell Cancer - Surveillance programs for stage I nonseminomatous germ cell tumors described

Glaucoma - Eyes with glaucoma compared with normal eyes for abnormalities

Glaucoma - InSite Vision announces positive trial results, prepares for AzaSite NDA

Glioblastomas - Intravenous compared to intraarterial ACNU administration in newly diagnosed glioblastomas

Gliomas - Glioma cell invasion enhanced by EFA6A

Graft-versus-Host Disease - Interleukin-18 levels are a useful indicator of acute graft-versus-host disease

Graft-versus-Host Disease - Women with breast or hematologic malignancy more likely to develop GI GVHD after ASCT

Gynecology - Menstrual cycle phases distinguished from underlying biological processes

HIV Transmission - Alkyl sulfate microbicides can be used to treat milk from HIV-1-positive women

HIV/AIDS Breast Feeding - HIV-infected mothers do not use formula milk because of social stigma and lack of resources

HIV/AIDS Dementia - HIV-1 Tat and methamphetamine synergistically destroy dopaminergic terminals in striatum

HIV/AIDS Diagnostics - Discordance between interpretation algorithms for HIV genotypes is subtype dependent

HIV/AIDS Diagnostics - HIV viral load assays compared

HIV/AIDS Diagnostics - HIV-1 replication capacity is measured by sensitive FACS-based method

HIV/AIDS Diagnostics - IFN-gamma alone may be insufficient to evaluate breadth of HIV-specific T cell response

HIV/AIDS Diagnostics - Researchers publish new studies and findings in the area of HIV/AIDS diagnostics

HIV/AIDS Drug Adherence - Adherence and response to HAART interaction requires multidisciplinary approach

HIV/AIDS Drug Adherence - HAART adherence improved in Mozambique with free drugs and laboratory testing

HIV/AIDS Drug Development - HIV-1 replication is inhibited in latently infected cells by I kappa B kinase inhibitor

HIV/AIDS Drug Monitoring - Antiretroviral drugs simultaneously detected in plasma by HPLC

HIV/AIDS Epidemiology - HIV drug resistance markers are epidemiologic sentinels for devising public health solutions

HIV/AIDS Evolution - HIV-1 env evolves toward ancestral states upon transmission to a new host

HIV/AIDS HAART - HAART needed by 6.5 million people in low- and middle-income countries by end of 2004

HIV/AIDS Microbicide - Preclinical nonoxynol-9 toxicity levels are standardized for HIV microbicide testing protocols

HIV/AIDS Pathogenesis - Basic residues in gag nucleocapsid domain required for HIV-1 Gag-ABCE1 interaction

HIV/AIDS Pathogenesis - HIV fusion to dendritic cells declines as cells mature

HIV/AIDS Pathogenesis - HIV integrase-E2C fusion protein strategy achieves site-specific integration

HIV/AIDS Pathogenesis - HIV-1-inducible short hairpin RNA and protein coexpression directed by pol II fusion promoter

HIV/AIDS Prevention - HIV transmission misunderstood by female intravenous drug users in Taiwan

HIV/AIDS Prevention - Mother-adolescent HIV prevention program increases condom use and improves communication

HIV/AIDS Prevention - Studies add new findings to HIV/AIDS prevention body of knowledge

HIV/AIDS Prognostics - Transformed variable Hsp70/CD4+ is less variable than Hsp70 for HIV prognosis

HIV/AIDS Research - U.S. NIH to initiate testing of Mymetics' HIV-AIDS mucosal prophylactic vaccine candidate

HIV/AIDS Therapy - Antiretrovirals not a magic bullet in reducing HIV infection rates; education still essential

HIV/AIDS Therapy - CD4 count at end of HAART interruption influences duration of first interruption

HIV/AIDS Therapy - Enfuvirtide therapy long-term outcome in HIV/AIDS is predicted by week-12 response

HIV/AIDS Therapy - HAART initiation after severe immunosuppression does not restore CD4+ counts in children

HIV/AIDS Therapy - HAART may reduce incidence of AIDS-related events in late-stage infection

HIV/AIDS Therapy - HAART protects against initial and subsequent AIDS-defining illnesses

HIV/AIDS Therapy - NRTI SPD754 is active against group M HIV-1 clades and has low myelotoxicity potential

HIV/AIDS Therapy - Research add new data to HIV/AIDS therapy body of knowledge

HIV/AIDS Therapy - Researchers' work adds to HIV/AIDS therapy body of knowledge

HIV/AIDS Vaccine - Fusion molecules could be the key to producing vaccines from plants

HIV/AIDS Vaccine - Juvaris receives SBIR Advanced Technology NIH-funded grant for HIV vaccine development

HIV/AIDS Vaccine - Multiple epitope-specific CTL responses control immunodeficiency virus replication

HIV/AIDS Vaccine - Novavax receives additional government funding for HIV/AIDS vaccine research

HIV/AIDS Vaccine - Peptide epitope of neutralizing HIV-1 antibody 4E10 analyzed

HIV/AIDS Wasting - Weight loss and wasting remain important AIDS-defining conditions

HIV/AIDS-Associated Lipoatrophy - Lipoatrophy improvement in lower extremities is associated with long-term stavudine withdrawal

HIV/AIDS-Related Depression - Factors associated with depression among homeless HIV-infected men identified

HIV/AIDS-Related Social Impact - HIV disease related to unemployment in France

HIV/Tuberculosis Screening - Chronic cough clinics for suspected TB are used to screen patients for HIV infection

Head & Neck Cancer - Cancer lymphangiogenesis may stem from inducible nitric oxide synthase activity

Head & Neck Cancer - Head and neck squamous cell carcinoma treated by carboplatin and radiotherapy

Head & Neck Cancer - Head and neck squamous cell carcinoma treated by docetaxel, cisplatin, and 5-fluorouracil

Head & Neck Cancer - Recent findings in head & neck cancer described

Head & Neck Cancer - Squamous cell head and neck cancer prognosticated by anemia

Health Promotion - Survey reveals percentage of parents don't trust government advice on vaccine safety

Healthcare Access - Prescription surveillance may increase racial disparities in access to medicines

Healthcare Access - Women and children are the first hurt by welfare reform

Healthcare Coverage - Aetna makes it simpler, easier for consumers to track, manage personal healthcare expenses

Healthcare Coverage - American Clinical Laboratory Association lauds deadline delay

Healthcare Coverage - Chrysler Group announces changes to employee health care plans effective next year

Healthcare Coverage - ConAPA's alternative to workers' comp legally lowers costs to California businesses

Healthcare Coverage - Del. Brown's bill to ensure access to cervical cancer screening passes West Virginia legislature

Healthcare Coverage - Diabetes advocates urge Senate HELP Committee to reject Enzi health insurance legislation

Healthcare Coverage - Health Net and Consulate General of Mexico collaborate to address gaps in Latino healthcare

Healthcare Coverage - Healthways expands HealthPlus of Michigan contract to provide disease-management services

Healthcare Coverage - Molina Healthcare Inc. is expanding its presence in both Medicare and Medicaid in Michigan

Healthcare Coverage - Mutual of Omaha to offer Healthways' myhealthIQ wellness program to group health customers

Healthcare Coverage - Premera Blue Cross Blue Shield of Alaska signs contract to administer state health plan

Healthcare Coverage - Priority Health implements Cave Consulting Group's Marketbasket system

Healthcare Coverage - UnumProvident reports cancer was top reason for long-term absence from work in 2005

Healthcare Coverage - Watson Wyatt collaborative survey finds employer interest in consumer-directed health plans

Heart Disease - Recent findings in heart disease provide new insights

Heart Failure - Advanced heart failure is independent predictor of inappropriate ICD shocks

Heart Failure - African American heart failure trial shows women, men both benefit from BiDil

Heart Failure - Biventricular pacing may be beneficial over univentricular pacing for resynchronization patients

Heart Failure - Coreg at hospital discharge associated with improved survival in heart failure

Heart Failure - Gene variations may determine which heart failure patients will benefit from BiDil

Heart Failure - Heart failure functional class and prognosis correlate with Doppler measures

Heart Failure - Heart failure severity linked to increased prevalence of sleep-related breathing disorders

Heart Failure - In mild, stable heart failure, metoprolol increases plasma B-type natriuretic peptides

Heart Failure - Leptin modulates cell size, MMP-2 expression, and collagen profile in human cardiomyocytes

Heart Failure - Pathways of matrix metalloproteinase induction in heart failure are focus of review

Heart Failure - Treatment of anemia with Aranesp may provide clinical benefits in heart failure patients

Hematology - Hemorrhage risk among patients with warfarin-associated coagulopathy is low

Hematology - Immobilized thrombin facilitates platelet adhesion and aggregation

Hematology - Neutrophil chemotaxis requires Hem-1 complexes

Hematology - Whole blood coagulation is used to guide hemostatic therapy

Hematopoiesis - Fetal hematopoiesis altered by genetic reduction of class IA PI-3 kinase activity

Hematopoiesis - Megakaryocytopoiesis is stimulated by arsenic trioxide through upregulation of GATA-2 expression

Hemodynamics - Cyclic strain urges vessel-like structures in 3D tissue culture models

Hepatitis B Virus - HBV X antigen downregulates E-cadherin in hepatocellular carcinoma

Hepatitis B Virus - HBV reverse transcriptase and epsilon RNA sequences are required for interaction

Hepatitis B Virus - Hepatitis B virus capsid plasticity is revealed by conformational stress

Hepatitis B Virus - New data illuminates research in hepatitis B virus

Hepatitis B Virus - Researchers report details of new studies and findings in the area of hepatitis B virus

Hepatitis C Virus - HCV RNA genotype is translationally enhanced by protein-coding sequences

Hepatitis C Virus - HCV down-regulation requires binding of ribosome domain and viral core protein

Hepatitis C Virus - HCV occurring after liver transplantation displays growth factor gene polymorphism

Hepatitis C Virus - HCV-positive patients differ in presentation of diffuse large B-cell lymphoma

Hepatitis C Virus - HGS reports positive interim phase IIb results for Albuferon in combination with ribavirin

Hepatitis C Virus - Hepatitis C immunopathogenesis is influenced by HIV co-infection

Hepatitis C Virus - Hepatitis C virus affects the expression of transferrin receptor 2

Hepatitis C Virus - Hepatitis C virus clinic treatment outcomes are comparable with clinical trials

Hepatitis C Virus - Hepatitis C virus is associated with very-low-density lipoprotein

Hepatitis C Virus - Hepatitis C virus treatment efficacy can be predicted

Hepatitis C Virus - Intrahepatic hepatitis C virus replication correlates with disease severity

Hepatitis C Virus - Quality of life of hepatitis C patients is affected by depression and smoking

Hepatitis C Virus - Recent studies add new data to hepatitis C virus research

Hepatitis C Virus - Researchers describe findings in hepatitis C virus studies

Hepatitis C Virus - Studies advance knowledge in hepatitis C virus research

Hepatitis Virus - Hepatitis virus strain JHM preferentially infects mature dendritic cells

Hepatocellular Cancer - Studies describe new findings in hepatocellular cancer research

Hepatocellular Carcinoma - Factors identified that are linked to early recurrence of hepatocellular carcinoma after resection

Hepatocellular Carcinoma - HCC changes occur after sustained interferon response to hepatitis C virus

Hepatocellular Carcinoma - HCC is influenced by alcohol consumption and ADH2 and ALDH2 gene polymorphisms

Hepatocellular Carcinoma - HCC proteomic profiling reveals heat-shock protein up-regulation

Hepatocellular Carcinoma - HCC tumorigenicity is reduced by knock-down of hepatitis B virus X protein

Hepatocellular Carcinoma - Hepatocellular carcinoma treated by menatetrenone, a vitamin K2 analog

Hepatocellular Carcinoma - Hepatocellular carcinoma treated by radiofrequency thermal ablation

Hepatocellular Carcinoma - Hepatocellular carcinoma treated by transcatheter arterial chemoembolization

Hepatocellular Carcinoma - Liver cancer angiogenesis could be restricted by Sprouty 2 regulation

Hepatocellular Carcinoma - Liver cancer growth, but not angiogenesis, responds to combination therapy

Hepatocellular Carcinoma - Primary HCC serum associated fucosylated glycoproteins may be diagnostic

Herpes Simplex Virus - Targeted herpes simplex virus testing may not be viable method to identify neonatal herpes

Herpes Simplex Virus - Treatment of intravaginal HSV-2 infection is aided by mucosal innate activation

High Cholesterol - Torcetrapib/atorvastatin research further supports raising good and lowering bad cholesterol

Hodgkin Lymphoma - Diagnosis of secondary malignancies after primary treatment of Hodgkin lymphoma could be difficult

Human Herpesvirus - Human herpes virus type 8 seroprevalence rate is intermediate-high and stable in Northern Sweden

Human Papillomavirus - Human papillomavirus-associated oropharyngeal cancers with favorable prognosis identified

Human Papillomavirus - Human papillomaviruses are genotyped by bead-based multiplex method

Human Papillomavirus - Study group urges establishment of international standard for HPV 16 antibodies

Human Papillomavirus Vaccine - Dendritic cell activation by HPV-16 vaccine involves a specific C-type lectin

Hyperglycemia - 5-HT reduces hyperphagia in NPY-overexpressing rat through action on 5-HT2A receptors

Hypertension - Coreg CR new drug application as blood pressure therapy accepted for review by U.S. FDA

Hypertension - High prevalence of hypertension is found with in-hospital 24-h blood pressure measurement

Hypertension - Hypertension and cardiovascular disease risk are linked to age, diabetes, and albuminuria

Hypertension - Hypertension may be adversely affected by swimming therapy in older women

Hypertension - Hypertension may be linked to ethnicity-specific regulator of G-protein signaling

Hypertension - In hypertension, ACE inhibition modulates vascular smooth muscle activation, wall remodeling

Hypertension - In hypertensive families, acute exercise reduces vascular reactivity to mental challenge

Hypertension - In idiopathic pulmonary arterial hypertension, arterial capacitance is predictor of mortality

Hypertension - In prehypertensives, impaired glucose tolerance raised cardiovascular disease risk

Hypertension - Initial studies show Aliskiren effective as hypertension drug

Hypertension - New data illuminates research in hypertension

Hypertension - Recent findings in hypertension provide new insights

Hypertension - Reports add new data to hypertension research

Hypertension - Researchers provide details of new studies and findings in the area of hypertension

Hypertension - Resting blood pressure reflects varied cardiovascular, sympathetic responses to mental stress

Hypertension - Salt substitute significantly reduces hypertension amongst rural Chinese

Hyperthyroidism - Induced Graves' hyperthyroidism is improved by adenovirus-encoded thyrotropin receptor

Hypotension - Clinical response to BiDil evaluated by baseline blood pressure

Hypoxia - Recent studies add new data to hypoxia research

Imaging - Dobutamine stress echocardiography sensitivity improves after beta blockade

Imaging - Imaging procedure speeds diagnosis of acute chest pain

Imaging - In suspected coronary artery disease, real-time perfusion-adenosine stress echocardiography may be useful

Imaging - MediSpectra receives U.S. FDA approval for the Luma Cervical Imaging System

Imaging - New Mexico Software signs X-Ray on Wheels to use web-based teleradiology PACS system

Imaging - New data illuminates research in imaging

Imaging - Nonlinear TT900 S2S now incorporates SameSpots for a new approach to 2D image analysis

Imaging - Optical coherence tomography is promising for imaging coronary atherosclerotic plaque

Imaging - Positron emission tomography targets oncolytic virus in prostate cancer therapy

Imaging - Pre-op MRI predicts left ventricular function after drug-eluting stent implantation

Imaging - Reports add new data to imaging research

Imaging - Reports describe recent advances in imaging research

Imaging - Researchers' work adds to imaging body of knowledge

Imaging - Speckle tracking echocardiography enables angle-independent measures of left ventricular strains

Imaging - Stress ECG, heart rate response to dobutamine should be included in image interpretation

Imaging - Studies advance knowledge in imaging research

Imaging - Studies describe new findings in imaging research

Imaging - U.S. FDA clears 3D imaging system with cardiac navigation technology

Imaging - U.S. FDA grants clearance for Toshiba's MRI system with advanced cardiac imaging applications

Imaging - Vulnerable plaques causing acute coronary syndrome are assessed using intravascular ultrasound

Immunotherapy - Connective tissue disease is induced with U1 small nuclear RNP autoantigen

Immunotherapy - Cytokine gene variants may affect efficacy of immunosuppressive, anti-inflammatory drugs

Immunotherapy - Heat labile Escherichia coli enterotoxin is potential adjuvant for transcutaneous cancer immunotherapy

Immunotherapy - Mirus Bio announces efficient new genetic immunization method to produce antibodies

Immunotherapy - Study to determine how to protect patients with weakened immune systems from influenza

Immunotherapy - T cell crosspriming in epithelial tissues is determined by dendritic cells

Immunotherapy - T cell-mediated oral tolerance is intact in germ-free mice

Incontinence - Transobturator sling is associated with decrease in obstructive voiding complications

Influenza Vaccine - Master donor virus for live attenuated influenza vaccines has been genetically mapped

Influenza Vaccine - Microbix technology yields significant increase in influenza virus for vaccine production

Influenza Virus - H5N1 influenza A virus detected by single step multiplex real-time RT-PCR assay

Influenza Virus - Nastech Pharmaceutical siRNA therapeutics effective in targeting and inhibiting influenza virus

Information Technology - Cedara Software introduces OrthoWorks ProPlanner

Information Technology - Central Illinois hospital system selects IT physician information system

Information Technology - Convergence CT completes technology integration at Kettering Medical Center Network

Information Technology - EPartnersMD software series for healthcare industry introduced by Microsoft consultancy

Information Technology - Invivodata integrates devices for patient-reported data recording in clinical trial

Information Technology - Invivodata to utilize Enfora's wireless modem cradle for clinical research data uploads

Information Technology - Kodak to support transition of BUPA's U.K. hospitals to digital medical imaging system

Information Technology - MedAvant converts customers to real-time claims processing engine, rolls out virtual call center

Information Technology - PMSI-Tmesys program guards patient safety by identifying potential drug-related risks

Information Technology - Premier unveils tool to analyze hospital supply spending

Information Technology - RelayHealth and SureScripts partner to provide eprescribing services

Information Technology - Software brings color to millions of color-blind users

Information Technology - Source Medical, MEDIBIS partner for integrated web-based business intelligence IT system

Information Technology - Substructure searchable inhibitor database files released by EMD Biosciences

Information Technology - Technology to improve care at the bedside and beyond

Information Technology - Verispan's informatics software identifies top 10 drug classes affected by Medicare Part D

Information Technology - Wolters Kluwer's drug dosing database licensed by Healthcare Management System Inc.

Injury Prevention - Coalition calls on tobacco companies to reduce cigarette-ignited fires and save lives

Interstitial Cystitis - Botulinum toxin type A may be a therapy for interstitial cystitis or sensory urgency

Ischemia - Hypercapnia uses nitrative stress to foil angiogenesis

Ischemia - Ischemic preconditioning requires increased reactive oxygen release apart from mitochondrial K+ activity

Ischemia - Myocardial perfusion is improved by tibolone therapy in women with ischemic heart disease

Ischemia - Post-conditioning reduces infarct size in the isolated rat heart

Ischemia - Post-conditioning-induced cardioprotection mechanisms are investigated

Ischemia - Transient ischemic episodes modulate brain damage through action of prostaglandin receptors

Kidney Disease - In long-term peritoneal dialysis, volume control is associated with better cardiac function

Kidney Disease - Renal dysfunction predicts higher mortality in patients with acute coronary syndrome

Kidney Transplant - Renal transplant dynamics can be tracked with contrast-enhanced ultrasound

Kidney Transplantation - Findings advance knowledge in kidney transplantation research

Klebsiella Outbreak -  Klebsiella pneumoniae mastitis outbreak caused by contaminated sawdust

Legal Issues - Federated Ambulatory Surgery Association files Friend of the Court brief with U.S. Supreme Court

Legal Issues - OrthoClear may continue suit against Align Technology, court rules

Legal Issues - U.S. District Court in Chicago dismisses action instituted by Abbott against Takeda

Legal Issues - Valeant Pharmaceuticals, Health Fund of Serbia settle dispute in joint venture Galenika

Leukemia - ATM gene promoter analysis of childhood lymphoid malignancies conducted

Leukemia - Acute myeloid leukemia linked to cyclin A1 expression

Leukemia - Adult T cell leukemia treated by curcumin

Leukemia - Frequency of chronic lymphocytic leukemia expressing VH 1-69 was low in Japanese

Leukemia - Myeloid leukemia cell differentiation involves a novel signaling molecule

Leukemia - New findings in the area of leukemia described

Leukemia - New findings in the area of leukemia detailed

Leukemia - New research in the area of leukemia detailed

Leukemia - Patients with acute myelogenous leukemia should receive consolidation before autotransplantation

Leukemia - Pre-B lymphoblastic leukemia cell aberrant splicing is induced by BCR-ABL1

Leukemia - Researchers publish new studies and findings in the area of leukemia

Leukemia - Smaller white-matter volumes linked to neurocognitive performance deficits among leukemia survivors

Leukemia - Studies add new findings to leukemia body of knowledge

Limb Regeneration - Satellite cell activation promotes salamander limb regeneration

Liposome Delivery - Cationic liposome decoy complex suppresses tumor necrosis factor alpha

Liposome Delivery - Liposome-DNA complexes inhibit tumor angiogenesis and elicit antitumor activity

Liver Cancer - Florida medical practice treats metastatic cancer using Varian image-guided radiotherapy technology

Liver Cancer - Liver cancer over-expresses angiogenesis growth factor

Liver Cancer - Liver cancer patients are often treatable

Liver Diseases - Non-alcoholic fatty liver disease is increasing among Korean adults

Lung Cancer - Histopathology of lung cancer in relation to radon exposure and silicosis analyzed

Lung Cancer - Lung cancer cannot be staged adequately by PET/CT of the chest during shallow breathing

Lung Cancer - Lung cancer treated by carboplatin/gemcitabine, an alternative therapy regimen

Lung Cancer - Lung cancer treated by irinotecan and cisplatin

Lung Cancer - Nonsmall cell lung cancer associated with cell-free circulating hTERT mRNA

Lung Cancer - Pharmacokinetics of amrubicin in lung cancer patients characterized

Lung Cancer - Quinuclidinone analogs examined as anti-proliferative agents in lung cancer

Lung Cancer - Reports describe recent advances in lung cancer research

Lung Cancer - Researchers describe findings in lung cancer studies

Lung Cancer - Resected non-small cell lung cancer linked to extreme chemotherapy resistance

Lung Cancer - Secular changes in sex-specific lung cancer incidence rates in urban Chinese population examined

Lung Cancer - Stage Ib lung cancer treated by sublobar resection with brachytherapy

Lung Cancer - Video-assisted thoracic surgery lobectomy for lung cancer evaluated

Lung Transplantation - Ex vivo evaluation called valuable for some nonacceptable donor lungs

Lymphoma - Lymphoma growth is sustained by fibroblast growth factor

Lymphoma - Lymphoma survival predicted by integrated clinical and gene expression data

Lymphoma - Studies describe new findings in lymphoma research

Macular Degeneration - Choroidal neovascularization increases following prophylactic laser therapy

Macular Degeneration - Vision loss from subfoveal choroidal neovascularization stabilizes with combination therapy

Malaria Drug Development - Antimalarial activity is seen in HIV protease inhibitors

Malaria Vaccines - New findings in the area of malaria vaccines described

Market Analysis - Counterpane & MessageLabs intelligence says cyber attacks will impact healthcare

Market Analysis - Deals between biotechnology companies and academic sector account for growth in licensing activity

Market Analysis - Drug companies incorporate Medicare Part D into strategy, structure

Market Analysis - HealthLeaders-InterStudy releases report on Colorado health plan consolidation

Market Analysis - India's global market share for the biotechnology industry is 1.1%

Market Analysis - Medical science liaison programs grow in popularity outside pharmaceuticals, study shows

Market Analysis - Publication examines physicians' online behaviors in Italy and Spain

Market Analysis - Ranks of pharmacists shrink as job demands grow

Market Analysis - Sleep-wake disorders market estimated at $4.3 billion, forecast to increase 158% by 2012

Market Analysis - Technology expenditure by the Virginia State Government predicted to be over $4.5 billion

Market Analysis - U.S. pharmaceutical launch advice given in new report

Market Analysis - Wireless patient monitoring systems growing in importance finds Frost & Sullivan report

Marketing - Allerex licenses rights to sell epinephrine auto injector in Canada to King Pharmaceuticals

Marketing - First Albany Capital hosts Chronic Pain Conference featuring physician panel

Marketing - Frito-Lay launches 100 Calorie Mini Bites line

Marketing - Helsinn and Pfizer sign a license agreement for the marketing of Aloxi in South Africa

Marketing - IDM and Medison Pharma sign an exclusive marketing agreement for Junovan in Israel

Marketing - Imalux commences Australia and New Zealand market development activity

Marketing - Neoprobe renews marketing agreement with Ethicon Endo-Surgery

Marketing - Report on CPOE systems shows Eclipsys' applications are most used by physicians

Marketing - Sinovac, LG Life Sciences sign agreement to market hepatitis B vaccine in China

Marketing - Toshiba 64-slice CT system ranked in KLAS survey at top in medical imaging technology

Marketing - Vertebron, medArtis sign exclusive agreement to distribute synthetic bone graft materials

Marketing - Vyteris' marketing partner launches transdermal drug delivery system in U.S. hospitals

Measles Surveillance - Measles surveillance algorithm reduces resource use during interepidemic periods

Medical Devices - ATS Medical reports first implant of Simulus annuloplasty ring

Medical Devices - Agilent launches sensitive triple quadruple mass spectrometer

Medical Devices - Centice debuts new Multimodal Multiplex Spectroscopy technology

Medical Devices - Conor Medsystems licenses pimecrolimus from Novartis for use in reservoir-based drug-eluting stents

Medical Devices - Cypher stent shown to outperform Taxus stent in long complex lesions

Medical Devices - Daxor announces publication of blood volume research study by Vanderbilt University and NIH

Medical Devices - Devon Medical Supplies, SafeTip Syringe make the grade in clinical testing

Medical Devices - Ingen announces that FDA evaluation for OxyView is complete

Medical Devices - Low adverse cardiac events rate using embolic protection system in SVG treatment reported

Medical Devices - Medtronic's Endeavor stent continues to show consistent clinical efficacy and strong safety profile

Medical Devices - Micrus Endovascular receives CE Mark for Courier microcatheter and Watusi guidewire

Medical Devices - Neuroscience Therapy introduces new electro stimulation device for acupuncture

Medical Devices - New findings in the area of medical devices detailed

Medical Devices - New research in the area of medical devices detailed

Medical Devices - NuVasive launches Gradient Plus anterior cervical plating system

Medical Devices - Recent findings in medical devices described

Medical Devices - ScottCare introduces Nicore Advantage external counterpulsation solution for cardiac patients

Medical Devices - U.S. FDA approves expanded labeling of Medtronic CRT biventricular pacing systems

Medical Devices - Varian adds Pursuit XRs high performance liquid chromatography columns to its lab products line

Medical Education - Virtual classroom proves better teacher for certain medical skills

Medicare - CMS conducting prescription drug plan enrollment campaign for selected Medicare beneficiaries

Medicare - Evercare launches educational outreach program to answer Medicare Part D questions

Medicare - Illinois health benefits company announces two Medicare supplement plans for seniors

Medicare - Ninety percent of low-income seniors surveyed expressed no problems using Medicare drug benefit

Medicare - Survey finds most Medicare drug enrollees are already saving

Medicare & Medicaid - Academy of Managed Care Pharmacy advocates changes in CMS Formulary Guidance

Melanoma - Dermatomyositis occurring in patients with malignant melanoma stage IV linked to poor prognosis

Melanoma - Impact of lymphoscintigraphy technique on outcome of sentinel node biopsy in melanoma discussed

Melanoma - Melanoma is regressed in a murine model by RLIP76 depletion

Melanoma - Melanosomal targeting sequences target epitope presentation and mobilization

Melanoma - Researchers detail new studies and findings in the area of melanoma

Melanoma - Researchers publish new studies and findings in the area of melanoma

Melanoma - Ultraviolet B sensitivity of lymphocytes identified as risk factor for melanoma

Melanoma Vaccines - New data illuminates research in melanoma vaccines

Melanoma Vaccines - Recent studies add new data to melanoma vaccines research

Melanoma Vaccines - Reports add new data to melanoma vaccines research

Meningiomas - Primary and recurrent meningiomas require new treatment strategies

Meningococcus Vaccine - Virulence is conserved in C to B capsule-switched Neisseria meningitidis

Mental Health - CompCare to launch disease management initiative to help U.S. Armed Forces returning from war

Mental Health - Faxed alerts to physicians may not improve patient antidepressant adherence

Mental Health - Female veterans find comfort level facilitates willingness to participate in therapy

Mental Health - Integrated treatment of psychiatric and substance use disorders is cost effective

Mental Health - Report finds North Carolina has shortage of psychiatrists

Mental Health - Reports advance knowledge in mental health research

Mergers & Acquisitions - Allergan receives final U.S. antitrust approval of Inamed acquisition

Mergers & Acquisitions - Allion Healthcare acquires H.S. Maiman RX, Inc.

Mergers & Acquisitions - AlloSource, U.S. Tissue and Cell join forces to create single source for allograft products

Mergers & Acquisitions - American Esoteric Laboratories acquires Physicians Medical Laboratory

Mergers & Acquisitions - American Medical Alert acquires MD On Call and Capitol Medical Bureau

Mergers & Acquisitions - AmerisourceBergen to acquire Canadian distributor

Mergers & Acquisitions - Andrx to be acquired by Watson for $25 per share

Mergers & Acquisitions - Angiotech's proceeds with acquisition of American Medical Instruments Holdings

Mergers & Acquisitions - Avantogen, Hawaii Biotech to combine vaccine businesses

Mergers & Acquisitions - China Health Holding plans to acquire Shaanxi Wanan Pharmaceutical

Mergers & Acquisitions - Contract research organization Kendle agrees to acquire Latin America CRO IC-Research

Mergers & Acquisitions - Fisher Scientific expands presence in molecular diagnostics, will acquire Athena Diagnostics

Mergers & Acquisitions - InSight Health Corp. acquires East Bay Medical Imaging

Mergers & Acquisitions - Independence Holding Company to acquire marketing organization

Mergers & Acquisitions - Integra LifeSciences closes acquisition of Radionics division of Tyco Healthcare

Mergers & Acquisitions - Kairos Holdings signs letter of intent to acquire interest in Health Plus International

Mergers & Acquisitions - MMS signs agreement to acquire Hospital Supply and Extended Care business of Henry Schein

Mergers & Acquisitions - Novoste sells vascular brachytherapy business to Best Vascular

Mergers & Acquisitions - Prionics acquires CEDI Diagnostics

Mergers & Acquisitions - Upstream Biosciences Inc. acquires common shares of genetic diagnostic marker company

Mergers & Acquisitions - Waters Corporation acquires VICAM's food safety technology business, associated net assets

Metastasis - Colorectal cancer liver metastasis may recur due to angiogenesis factors after resection

Methionine Kinetics - Methionine kinetics are altered in the elderly before and after vaccination

Microtechnology - Changes in the visual word processing network fine tuned beyond adolescence

Microtechnology - Confocal microprobe Raman imaging of urban tropospheric aerosol particles is evaluated

Microtubules - Flexural rigidity of individual microtubules measured by a buckling force with optical traps

Migraine Headache - NMT Medical's MIST study indicates that closing a PFO has an effect on migraine

Molecular Biology - Molecular interactions govern VEGF-induced endothelial cell proliferation

Multiple Myeloma - Early multiple myeloma treatment failure is initiated by synergy between cyclin D2 and CKS1B

Multiple Myeloma - Multiple myeloma peripheral blood progenitor cells are mobilized and harvested by pegfilgrastim

Multiple Myeloma - Multiple myeloma responds to thalidomide monotherapy

Multiple Sclerosis - Oligodendrocyte glycoprotein antibodies are diagnostic of early inflammation in multiple sclerosis

Mycobacteria Diagnostics - Slow growing Mycobacterium species directly identified by 16S-23S rDNA ISR analysis

Myelodysplastic Syndrome - Study recommends treatment change for pre-leukemia disease

Myeloma - Multiple myeloma is rarely associated with PTEN deletions and mutations

Myeloma - Multiple myeloma overexpressed genes identified in chromosome regions

Myeloma - Outcome of myeloma not improved with addition of valspodar

Myocardial Infarction - For myocardial infarction diagnosis, studies are needed to define optimal troponin threshold

Myocardial Infarction - Remodeling after myocardial infarction is unaffected by deletion of NADPH oxidase subunit

Nanotechnology - Alltracel develops nano-fiber delivery platform for wound care technology

Nanotechnology - Do-Coop Technologies launches new Neowater program and kit at 2006 qPCR Conference

Natural Products - 5,6:8,9-Diepoxy and other cytotoxic sterols isolated from marine sponge

Nephroblastoma - Wilms tumor complicated by liver metastases linked to less favorable outcome

Neural Stem Cell Research - Brain function improved by G-CSF and SCF administration after stroke

Neurogenesis - Neural stem cell differentiation into cholinergic neurons affected by bFGF and heparin

Neurogenesis - Researchers' findings advance neurogenesis research

Neurology - Electrical impulses found to foster myelination in brain cells, speeding communications

Neuropathic Pain - Lacosamide results statistically significant in diabetic neuropathic pain phase III trial

Neuropathy - Dichloroacetate causes toxic neuropathy in MELAS in clinical trial

Neuroscience - Basic FGF expression in astrocytes affects dopamine neuron synaptic function and development

Neuroscience - Extracellular matrix-degrading proteases affect spatial learning and synaptic plasticity

Neuroscience - GABAB receptors mediate inhibitory action via calcium and potassium channels

Neuroscience - Neuroticism mediates serotonin transporter gene association with lifetime major depression

Neuroscience - Neurotoxicity is attenuated by adenoviral gene transfer of superoxide dismutase

Neuroscience - Researchers discover technique to stimulate brain growth in hatchery-reared fish

Neuroscience - Schizophrenia may result in part from impaired D-4 mediated downstream signaling

Neuroscience - Serotonin receptors remain engaged after damage to the serotonergic system

Nipah Virus-Associated Encephalitis - Nipah virus-associated encephalitis outbreak in India confirmed by RT-PCR

Non-Alcoholic Steatohepatitis - Non-alcoholic steatohepatitis predictors of fibrosis identified

Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma treated with less intensive therapy

Norovirus Transmission - Feline calicivirus can survive for several days on fomites

Nosocomial Infections - Findings describe new data in nosocomial infections research

Obesity Complications - Carotid artery stiffness and C-reactive protein were linked to metabolic syndrome in obese

Obesity Complications - Macrophage-secreted factors influence inflammatory and insulin responses in adipocytes

Obesity Epidemiology - Interventions to social environment at community level may offer obesity treatment option

Obesity Epidemiology - Obesity related to insulin resistance adaptation mechanisms are similar across ethnic groups

Obesity Epidemiology - PPARGC1A Gly482Ser polymorphism is linked to high obesity risk in physically inactive

Obesity Epidemiology - Rapid weight gain in infancy and early childhood is adiposity and obesity risk factor

Obesity Epidemiology - Weight gain was linked to sugar-sweetened drink and fatty food intake in Mediterranean cohort

Obesity Pathogenesis - CD11b expression and endothelial cell adhesion in monocytes is linked to high fatty acid levels

Obesity Pathogenesis - ELOVL3 is important for early onset of lipid recruitment in brown adipose tissue

Obesity Pathogenesis - Findings in obesity pathogenesis provide new insights

Obesity Pathogenesis - Leptin has a common link to obesity and hypertension

Obesity Pathogenesis - POMC variant implicates beta-MSH in the control of human energy balance

Obesity Pathogenesis - Recent studies add new data to obesity pathogenesis research

Obesity Pathogenesis - Researchers detail new studies and findings in the area of obesity pathogenesis

Obesity Pathogenesis - Researchers provide details of new studies and findings in the area of obesity pathogenesis

Obesity Pathogenesis - Researchers publish new studies and findings in the area of obesity pathogenesis

Obesity Pathogenesis - Treating adipocytes as endocrine organs is leading to new insights into obesity

Obesity Pathogenesis - p/CIP and SRC-1 play key roles in energy balance by controlling energy intake and expenditure

Obesity Pathogenesis - p38MAPK negatively influences adipogenesis by inhibiting C/EBP beta and PPAR gamma transcription

Obesity Prevention - Mayo Clinic obesity researchers test classroom of the future

Obesity Prevention - Obesity prevention in youth needs to involve politics, science, and healthcare

Obesity Research - Obesity risk in women may be related to socioeconomic status in childhood

Obesity Surgery - Mayo Clinic researchers say bariatric surgery may reduce risk of heart disease

Obesity Therapy - Botulinum toxin A reduces appetite and may be a potential obesity treatment

Obesity Therapy - Cardiovascular fitness in obese improved by 'Walking for pleasure'

Obesity Therapy - Conservative weight loss is better option for morbid obesity therapy in some patients

Obesity Therapy - Quality of life improved by surgical procedures in severely obese patients

Obesity Therapy - RYGB in high-obesity risk patients was related to a decline in fatty food preference

Obesity Therapy - Total abdominal liposuction followed by abdominoplasty is proposed for massive weight loss

Obstetrics - Adult hypertension and chronic kidney disease may be associated with low birth weight

Obstetrics - Birth weight may be associated with maternal glucose levels during third trimester

Obstetrics - Caesarean section may not be determining factor for women to avoid future pregnancies

Obstetrics - Changes in fetal echocardiography referral trends are focus of review

Obstetrics - Group B streptococcal colonization has inverse association with preterm delivery

Obstetrics - Increasing calcium intake during pregnancy may reduce bone loss during gestation/lactation

Obstetrics - Maternal health progress requires poverty reduction/health system improvements

Obstetrics - Physical activity of mice during pregnancy appears to stimulate brain cell growth in offspring

Obstetrics - Pregnancy complications increase women's risk of heart disease, death

Obstetrics - Prenatal iron supplementation may increase mean birth weight and lower preterm delivery

Obstetrics - Prenatal pesticide exposure may lead to high blood pressure, decreased neurological ability

Obstetrics - Rise in maternal pregestational diabetes corresponds to increased birth complications

Obstetrics - Small birthweight and premature births associated with higher risk of child abuse

Obstetrics - Thyroid disorder screening during pregnancy could be enhanced by standardization

Obstetrics - Thyroid function testing during specific intervals enhances monitoring during pregnancy

Occupational Exposure - Compliance inadequate for prevention of occupational exposure to blood and body fluids

Oncology - Findings describe new data in oncology research

Oncology - New findings in the area of oncology detailed

Oncology - Tumor angiogenesis and monocyte trafficking are driven by integrin interaction

Oncology - Urothelial cancer displays matrix metalloproteinase localization

Ophthalmology - Corneal neovascularization can be limited by antiangiogenic therapy after low-risk keratoplasty

Ophthalmology - Neurotech's NT-501 can be safely implanted into the eye, well tolerated by patients

Ophthalmology - Researchers report details of new studies and findings in the area of ophthalmology

Ophthalmology - Single dose of azithromycin prevents recurrence of inturned eyelashes

Osteoporosis - Bone mineral density is reduced in distal limbs of women with primary hyperparathyroidism

Osteoporosis - Effect of bone aging on maxillofacial skeleton and osteoporosis development is focus of review

Osteoporosis - NPS Pharmaceuticals receives approvable letter for Preos NDA from U.S. FDA

Osteoporosis - New study shows women with osteoporosis prefer treatment in one tablet per month

Osteoporosis - Osteoporosis risk may be higher in women with altered inferior cortex morphology

Outbreak Surveillance - Surveillance networks linked by Global Outbreak Alert and Response Network

Ovarian Cancer - Data advance knowledge in ovarian cancer research

Ovarian Cancer - Effective ovarian cancer treatment strategies target Raf-1 mRNA

Ovarian Cancer - Mdr-1 polymorphism G2677T/A correlates with paclitaxel response in ovarian cancer

Ovarian Cancer - Ovarian cancer progression is predicted preoperatively by angiogenesis protein

Overactive Bladder - Only four percent of Americans with bladder problems seek medical help

Pacemakers - Pacemaker patients benefit from upgraded biventricular pacing

Palliation - Improved chemotherapy drugs improve quality of life for bone marrow cancer patients

Pancreas Disease - Salmonid alphavirus detected by sensitive and specific real-time PCR assay

Pancreatic Cancer - Pancreatic cancer cells react to structurally optimized celecoxib derivative

Pancreatic Cancer - Pancreatic head carcinoma in elderly patients can be treated by surgery but with risks

Pancreatitis - Scientists discover secret of coffee's beneficial effect on pancreatitis

Parasitology - Inhibitors of aquaporins may yield novel therapeutic agents for microsporidian infections

Parkinson Disease - Research add new data to Parkinson disease body of knowledge

Patents - Clearant awarded two new U.S. patents on pathogen inactivation technology

Patents - CombiMatrix granted nanotechnology patent enabling unique proteomics technology and products

Patents - EntreMed's patent covers broad range of indications for 2-methoxyestradiol

Patents - HemoCue prevails in patent infringement suit over hemoglobin testing product

Patents - Nanogen issued U.S. patent for integrated sample preparation and detection device

Patents - PTS, Inc.'s Glove Box granted U.S. patent

Patents - Patent issued to the University of Pittsburgh for 2-methoxyestradiol for diabetes

Patents - U.S. patent office issues broad Invader Plus patent to Third Wave Technologies

Pediatric Cardiology - Researchers' data advance pediatric cardiology research

Pediatric Diabetes - Adolescents with diabetes have friendships that are similar to those among healthy

Pediatrics - National survey reveals need for DHA education among new moms

Pediatrics - Use of high humidity does not improve symptoms for children with croup

Pelvic Surgery - Pelvic surgery with the Siremobil Iso-C-3D imaging system evaluated

Peptic Stenosis - Scintigraphy utilizing Tc-99m is an effective method to assess improvement in gastric function

Periampullary Tumors - Periampullary tumors with CT grades A to D staged with laparoscopic ultrasound

Peritoneal Dialysis - Peritoneal membrane failure is launched by irregular mesothelial cell transitioning

Personnel - AAIPharma announces new chief financial officer

Personnel - AMS Health Sciences elects new board member

Personnel - Acorda Therapeutics adds Lorin J. Randall to board of directors

Personnel - Adeza appoints Greg Vontz to board of directors

Personnel - Allos Therapeutics appoints Paul L. Berns as president and CEO

Personnel - Aptuit names Kurt S. Mussina as VP, sales and marketing

Personnel - Beckman Coulter announces management change

Personnel - Cardium adds Kelly D. Scott as vice president of new medical technology business

Personnel - Christopher Twomey joins board of directors of Senomyx, Inc.

Personnel - Click4Care welcomes John McGahey to executive team

Personnel - Coalition America CEO and Chairman Sean Smith elected to AAPPO board

Personnel - Codexis announces senior appointments at new enzymes and intermediates business

Personnel - CombiMatrix Molecular Diagnostics names Dr. Mansoor Mohammed CSO and to board

Personnel - Dendreon names Mark Frohlich vice president of clinical affairs

Personnel - Donald L. Resnick, MD, joins Franklin & Seidelmann network as subspecialty radiologist

Personnel - Dr. Alan Ezekowitz joins Merck Research Laboratories in key leadership role

Personnel - Dr. Judith Hemberger joins ZymoGenetics board of directors

Personnel - Elder Health, Inc. names Jeffrey M. Folick new CEO

Personnel - Floyd retires as BEI chairman, CEO

Personnel - Frances W. Preston joins Bionovo's board of directors

Personnel - G. Taylor Wilson joins Cirrus Health leadership team

Personnel - Gary Gensler named to board of consumer health spending management company WageWorks

Personnel - Genetic Technologies Limited appoints Norbet Bachl to its scientific advisory committee

Personnel - Guidant Cardiac Rhythm Management President R. Frederick McCoy elects early retirement

Personnel - HealthPoint names Rob Bancroft as senior vice president, sales and marketing for tissue management

Personnel - Herbalife adds Belong Cho, MD, of Korea, to medical advisory board

Personnel - Hoana Medical names Robert Wachter to its medical advisory board

Personnel - Holmes Herbs names Mohammed A. Quader, MD, as chief scientific advisor

Personnel - Icagen announces retirement of Heyward Hull, senior VP

Personnel - Illinois Children's Health Foundation names Floyd D. Perkins to board

Personnel - ImaRx Therapeutics bolsters executive team

Personnel - ImmuneRegen BioSciences appoints Kelly McQueen to advisory board

Personnel - InNexus appoints chief financial officer

Personnel - Ingen Technologies names Dr. Michael Koch to its advisory board

Personnel - Innovative Spinal Technologies adds Todd Fanning to the executive management team

Personnel - Inotek Pharmaceuticals hires Emma Reeve as chief financial officer

Personnel - Institute for Cellular Medicine names Dr. Miguel Bedolla to ethical advisory board

Personnel - Jeff L. Myers named chief of pediatric cardiothoracic surgery at Le Bonheur medical center

Personnel - Joel Lajeunesse named VP, division head of pharmacy, at M.D. Anderson Cancer Center

Personnel - Joimax names Michael Stek CEO for U.S. activities, finalizes new board of directors

Personnel - Julie M. Eastland named chief financial officer of biotech company VLST Corp.

Personnel - Lindal Ollis named CEO of Creighton University Medical Center by Tenet California

Personnel - Lumenis announces resignation of Darrell S. Rigel from company's board of directors

Personnel - Marc Burel named VP of domestic sales by medical device company Vertebron

Personnel - Mark P. Backer, PhD, appointed president and CEO of West Coast Biologicals, Inc.

Personnel - Med-Vantage announces expansion of senior management team

Personnel - MedCath names Phil Mazzuca as chief operating officer

Personnel - MedImmune broadens management team with five additional leaders in key strategic areas

Personnel - MedSolutions appoints Stephen Mengert as chief financial officer

Personnel - MedVenture Associates expands partnership with addition of Robert Brownell

Personnel - MediCor names Paul R. Kimmel as chief financial officer

Personnel - Medistem appoints Roger M. Nocera as executive vice president and chief medical officer

Personnel - Met-Pro corporation names James G. Board and Paul A. Tetley as executive vice presidents

Personnel - Michael Shoup named SurModic's VP of quality, regulatory and clinical affairs

Personnel - NIH Research appoints Stephanie P. Massengill as chief executive officer

Personnel - National Cancer Coalition creates international advisory council

Personnel - National Health Investors to end use of National HealthCare Corporation advisors

Personnel - National Medical Health Card Systems names G. Harry Durity chairman of board of directors

Personnel - Par Pharmaceutical names Gerard A. Martino as chief financial officer

Personnel - PhRMA elects Peter R. Dolan as board chairman, seeks to improve access to medicines

Personnel - PolyMedix elects William Kelley, MD and Shaun O'Malley to board of directors

Personnel - Pozen appoints Donald H. Namm and James J. Mauzey to its board of directors

Personnel - Renowned retinal specialist Alan Bird joins iCO Therapeutics' strategic advisory team

Personnel - Santo J. Costa, JD, appointed to board of directors of Labopharm Inc.

Personnel - Schering-Plough announces changes in executive finance positions

Personnel - Seattle Genetics appoints Dr. Daniel Hoth to board of directors

Personnel - Sheren Ghali named vice president of human resources of WageWorks

Personnel - Sirna Therapeutics announces members of scientific advisory board

Personnel - St. Francis Medical names Andrew Caudell European director of sales and marketing

Personnel - Sterling Healthcare names Eugene F. Dauchert, Jr. CEO and G. Scott Dillon COO

Personnel - Tracon Pharmaceuticals names key management team members to help develop cancer therapy pipeline

Personnel - Vesta Therapeutics names four researchers to newly formed scientific advisory board

Personnel - Vinand Nantulya, MD, named senior policy, implementation officer by diagnostics foundation

Personnel - Voyager Pharmaceutical adds Tommy G. Thompson, five more new members to board of directors

Personnel - Werner Hacke, PhD, named to LION bioscience's new supervisory board

Pharmaceutical Research - Best Practices introduces Best Practice and Benchmarking Database for biotech companies

Pharmaceutical Research - Cutting Edge Information study shows real-world data drive line extensions

Pharmaceutical Research - Engineering Fc region of antibodies raises toxicity to cancer cells, Xencor research shows

Pharmaceutical Research - Production restructuring in pharma companies to propel fine chemicals market in North America

Pharmaceutical Research - Thalidomide shows no interaction with P-glycoprotein

Pharmaceutical Research - Top pharma copromotions start with detailed contracts

Pharmacology - A bromoenol lactone suicide substrate inactivates group VIA

Pharmacology - Pharmacokinetics of anidulafungin in children with neutropenia studied

Pheochromocytomas - Pheochromocytoma linked to clusterin expression

Philanthropy - Holland America Line sponsors "On Deck for the Cure" to raise money to fight breast cancer

Physiological Stress - Physiological stress in response to bullying in the workplace was evaluated

Physiology - Intermedin activates aortic L-Arg/nitric oxide synthase/nitric oxide pathway

Physiology - Intracellular pH modulates taste receptor cell volume and response to acids

Physiology - Novel targets identified in a phosphatidylinositol 3-kinase-independent pathway

Physiology - RNA interference-based screen identifies MAP4K4/NIK as a negative regulator

Pneumococcus Epidemiology - Pneumococcal clones not widely distributed in disease-causing isolates in Scotland

Pneumococcus Vaccine - Pneumococcal vaccination is unaffected by splenectomy

Pneumococcus Vaccine - T cell responses increase with age and determine antibody response and protective efficacy

Pneumonia - CCL5 may be key factor for induction, maintenance of protective pneumococcal immunity

Pneumonia - Contagious pleuropneumonia transmission and control has been modeled

Polio Vaccines - New findings in the area of polio vaccines described

Preventive Medicine - Sun safety curriculum improved middle school students' knowledge of sun protection

Prison Health - As inmate population ages, prison system must adapt to meet healthcare needs, say researchers

Product Licensing - Berlex signs license agreement with GeneGo

Product Licensing - Norwood Abbey signs commercial-phase license agreement with MIT for needle-free injection system

Product Licensing - Nu Skin Enterprises acquires additional Pharmanex BioPhotonic Scanner rights

Product Licensing - Tm Bioscience licenses P450 pharmacogenetic biomarker from Epidauros Biotechnologie AG

Professional Education - Cynosure inks agreement for accredited courses for women's health

Prognostics - Clinical factors used to select patients who would benefit from hepatic metastasectomy

Prostate Cancer - Bone implants in SCID mice evaluated as a model of prostate cancer bone metastasis

Prostate Cancer - Cell Genesys to present data from two GVAX cancer immunotherapy clinical trials

Prostate Cancer - Detection of bone metastases from high-risk prostate cancer improved by SPECT

Prostate Cancer - Hormone-sensitive prostate cancer treated with zoledronic acid therapy

Prostate Cancer - Human prostate cancer is associated with G-protein coupled receptor overexpression

Prostate Cancer - Impact of prostate cancer diagnosis on patients' mental health evaluated

Prostate Cancer - Pathological characteristics of prostate cancer discussed

Prostate Cancer - Prostate cancer diagnosed after repeat biopsies linked to favorable prognosis

Prostate Cancer - Prostate cancer epithelial cell channels display differential roles

Prostate Cancer - Prostate cancer linked to 90K/Mac-2 binding protein expression

Prostate Cancer - Prostate cancer malignancy linked to Aurora B expression

Prostate Cancer - Prostate cancer predicted by prostate specific antigen in black American men

Prostate Cancer - Prostate cancer screening in high-risk African American men discussed

Prostate Cancer - Prostate cancers are effectively treated using oncolytic herpes simplex virus

Prostate Cancer - Regressive changes after antihormonal therapy in prostatic carcinoma analyzed

Prostate Cancer - Reports advance knowledge in prostate cancer research

Prostate Cancer - Research add new data to prostate cancer body of knowledge

Prostate Cancer - Researchers describe findings in prostate cancer studies

Prostate Cancer - Researchers provide details of new studies and findings in the area of prostate cancer

Prostate Cancer - Researchers' work adds to prostate cancer body of knowledge

Proteomics - Amphotericin B's antifungicidal activity is inhibited by protein binding

Proteomics - Caprion Pharmaceuticals announces acquisition of novel therapeutic peptide applicable in oncology

Proteomics - Crystal structure of apolipoprotein A-I offers insights into its protective cardiovascular effect

Proteomics - Deformability, dynamics, and remodeling of cytoskeleton of adherent living cells are considered

Proteomics - Endogenous factors influence angiogenin production

Proteomics - Macrophage cholesterol homeostasis and inflammation involves adipocyte enhancer-binding protein 1

Proteomics - Metabolic acidosis is mediated by a p38 signaling pathway

Proteomics - Nonstructural protein 5A possesses conserved membrane anchoring regions

Proteomics - Proteomics of the heart and the study of cardiovascular disease are focus of review

Proteomics - The angiogenesis inhibitor histidine-rich glycoprotein disrupts endothelial cell movement

Proteomics - University of Illiniois chemists devise method makes ligation reactions permanent

Public Health - Commission report indicates Australia has benefited from spending on innovation in health care

Quality Assurance - Henry Ford Hospital selects ValiMed from CDEX for medication validation

Quality Assurance - Medco Health Solutions' RationalMed receives NCQA Disease Management Systems Certification

Quality Assurance - National Quality Forum report details success stories of implementing consensus standards

Quality Assurance - Stratagene's Texas facility achieves ISO 13485 registration as medical devices developer

RNA Interference - RNA interference allows transgenic screening

Radiotherapy - Link between quality of life and fatigue in cancer patients receiving radiotherapy assessed

Radiotherapy - Non-small cell lung cancer treated by stereotactic hypofractionated radiotherapy

Radiotherapy - Sulfoquinovosylmonoacylglycerol sensitizes tumor vessels to radiation therapy

Rectal Cancer - Technique of total mesorectal excision in rectal cancer surgery described

Renal Angiomyolipomata - Renal angiomyolipomata in patients with tuberous sclerosis complex treated by embolization

Renal Cell Carcinoma - Renal cell carcinoma prognosticated by platelet count

Renal Rhabdomyosarcoma - Case of puerperal renal rhabdomyosarcoma described

Renal Tumors - Renal tumors treated by radiofrequency ablation

Research Reporting - Bibliometric assessment of prevention research impact is feasible but of limited utility

Respiratory Medicine - Positive pressure-assisted breathing alters sympathetic baroreflex drive

Respiratory Medicine - Sleep-related breathing disorder therapies must be determined individually

Respiratory Medicine - Team proposes national tuberculosis archive

Respiratory Syncytial Virus - RSV genetic variation characterized from consecutive acute respiratory infection isolates

Restructuring - QuadraMed aligns resources to streamline operations

Rhabdomyosarcomas - Mel-resistant rhabdomyosarcoma cells sensitized to melphalan by TRAIL

Rhabdomyosarcomas - Rhabdomyosarcoma should be treated by complete tumor resection prior to chemotherapy

SARS - Researchers provide details of new studies and findings in the area of SARS

SARS - SARS coronavirus triple-spanning membrane proteins are glycosylated

SARS Infection Control - SARS spread among healthcare workers minimized by integrated infection control

SARS Outbreaks - SARS spread may be contained through early recognition and prompt isolation

SARS Prevention - SARS prevention program initiation decreases nursing staff anxiety and depression

SIDS - A genetic variant is probable cause of increased SIDS in African Americans

Sacrococcygeal Teratoma - Factors relating to sacrococcygeal teratoma recurrence in children examined

Sexual & Reproductive Health - Chronic pelvic pain may correlate to COX-2 overexpression in peritoneal lesions

Sexual & Reproductive Health - Chronic pelvic pain patients may have history of suppressed emotions and abuse

Sexual & Reproductive Health - Continuous hormone therapy with 17beta-estradiol dydrogesterone appears effective and safe

Sexual & Reproductive Health - Levonorgestrel intrauterine system results in better outcomes for menorrhagia

Sexual & Reproductive Health - Planned Parenthood Southeastern Pennsylvania kicks off $6 million awareness campaign

Sexual & Reproductive Health - Risk of lower back pain may be increased in women with past gynecological surgeries

Sexual & Reproductive Health - Serotonin-induced sexual dysfunction in women may be reversed with tadalafil therapy

Sexual & Reproductive Health - Study shows lifestyle and health related to satisfying sex life as men age

Sexual & Reproductive Health - Transdermal estrogen therapy appears safe/effective for women having vaginal hysterectomy

Sexual & Reproductive Health - Transvaginal ultrasound-guided polypectomy was evaluated for endometrial polyp removal

Skin Cancer - Researchers link human papillomavirus to common skin cancer

Sleep Apnea - Sodium oxybate formulation available as narcolepsy treatment, Jazz Pharmaceuticals reports

Smallpox Vaccine - Atopic dermatitis may lead to deadly complications from smallpox vaccine

Smallpox Vaccines - Recent findings illuminate research in smallpox vaccines

Smallpox Vaccines - Reports add new data to smallpox vaccines research

Soft Tissue Sarcomas - Soft tissue sarcoma should not be treated with gemcitabine as first-line chemotherapy

Solitary Fibrous Tumors - Case of solitary fibrous tumor of the larynx reported

Splenectomy - Post-splenectomy infection risk called an important health problem

Squamous Cell Carcinoma - Incidence of squamous cell carcinoma in Zimbabwean population described

Squamous Cell Carcinoma - Oral squamous cell carcinoma linked to WWOX gene alterations

Squamous Cell Carcinoma - Poor prognosis in oral squamous cell carcinoma linked to reduced E-cadherin expression

Squamous Cell Carcinoma - Squamous cell carcinoma of the esophagus staged by preoperative laparoscopy

Squamous Cell Carcinoma - Squamous cell carcinoma of the head and neck linked to p16 gene alterations

Staffing - IPC to provide inpatient care at Florida Hospital Zephyrhills

Staffing - Medical transcription recognized as apprenticeable occupation by U.S. Department of Labor

Staffing - Premier designates Private Eyes as supplier for background checks for member hospitals

Staffing - Retention initiatives rise as physician turnover concerns increase

Statins - Findings advance knowledge in statins research

Statins - In rat model of heart failure, pravastatin increases survival, suppresses MMP activity

Statins - Pravastatin inhibits expression of lectin-like oxidized LDL receptor-1

Statins - Recent studies add new data to statins research

Statins - Reports advance knowledge in statins research

Statins - Statin anti-inflammatory properties involve peroxisome proliferator-activated receptor-alpha

Statins - Statin-related adverse events are synthesized in a meta-analysis of clinical trials

Statins - Statins are suggested to have anti-arrhythmic properties

Stem Cell Research - Activated NK cells are capable of killing mesenchymal stem cells

Stem Cell Research - Adult stem cells improve cardiac function, blood flow in patients with heart disease

Stem Cell Research - Allogeneic hematopoietic stem cell transplantation is a potent immunotherapy

Stem Cell Research - Fluid flow-induced MSC proliferation mediated by MAP kinase and calcium signaling

Stem Cell Research - Genetically corrected Fanconi anemia bone marrow cells can repopulate

Stem Cell Research - Research into the behavior of leukemic cells may enhance recovery from radiation and chemo

Stem Cell Research - Researchers find viable new sources for stem cell transplants to the heart

Stem Cell Research - Stem cell-derived dendritic cells induce immunity against metastatic melanoma

Stem Cell Research - Stem cells improved left ventricle wall thickness, capillary density following heart attack

Stem Cell Research - miRNA analyzed in single cells by real-time PCR-based 220-plex miRNA expression profiling

Stem Cell Therapy - Grafted MSCs differentiate into neural cells and improve motor function in ischemic brain

Stem Cell Transplantation - ASCT is feasible in selected elderly patients with non-Hodgkin lymphoma

Stem Cell Transplantation - Natural killer-cell lineage neoplasms treated by hematopoietic SCT therapy

Stem Cell Transplantation - Post-hematopoietic stem cell transplant G-CSF does not affect risk of GVHD or survival

Stem Cell Transplantation - Reports describe recent advances in stem cell transplantation research

Stem Cell Transplantation - Stem cell transplant survival in CML associated with higher 30-day lymphocyte count

Stem Cell Transplantation - Transplant-related mortality increased in non-Caucasians undergoing standard sibling SCT

Streptococcal Diseases -  Streptococcus equi SeM gene sequence variation discriminates outbreak source

Stroke - A neuroactive steroid may be a useful co-therapy with thrombolytics for stroke

Stroke - Cardiovascular risk factors and 5-year mortality in Copenhagen stroke study are reported

Stroke - Clopidogrel and aspirin did not reduce heart attack, stroke, or cardiovascular death risk in study

Stroke - DP-b99 phase II study recommended for continuation by ISMB, says D-Pharm

Stroke - For patients with atrial fibrillation, discontinuing warfarin over time is a cause for concern

Stroke - Landmark trial shows carotid stenting beneficial for patients at risk for standard surgery

Stroke - Reimbursement practices and public health efforts critical to improve stroke reporting, outcomes

Stroke - Renovis' NXY-059 for intracerebral hemmorhage phase IIb trial met primary endpoints

Stroke Therapy - Robotic arm lends a hand to stroke patients at Minnesota hospital

Substance Abuse - CompCare launches substance abuse disease management solutions using Hythiam protocols

Surgical Technology - Bladder cancer treated by virtual cystoscopy via instillation of dilute contrast medium

Surgical Technology - Enchondroma of the hand treated with injectable calcium phosphate bone cement

Surgical Technology - Innocoll receives approval to promote its Gentamicin surgical implant in Norway

Surgical Technology - Large-model femoral bypass graft exhibits better hemodynamics than smaller version

Surgical Technology - Michigan hospital utilizes Spy Intra-operative Imaging System to confirm success of heart surgery

Surgical Technology - New findings in the area of surgical technology described

Surgical Technology - Paclitaxel-eluting stent use, lumen diameter, and lesion length were predictors of restenosis

Surgical Technology - Praxim Medivision announces plans to enter U.S. market

Surgical Technology - Restenosis is frequent after SES implantation for unprotected left main coronary artery lesions

Surgical Technology - Sirolimus-eluting stents induced redistribution of memory T lymphocytes in coronary sinus

Surgical Technology - Stent registry safety data favors Taxus over Cypher in complex diabetic patients

Surgical Technology - Subtotal esophagectomy for esophageal cancer performed using supercharge technique

Telemedicine - Low-income patients may reduce heart disease risk via internet

Testicular Seminoma - Treatment of testicular seminoma by adjuvant chemotherapy evaluated

Therapeutic Drug Monitoring - Therapeutic drug monitoring before HSCT improved by pharmacokinetic sampling strategy

Thyroid Cancer - Metastatic thyroid carcinoma restaged in real-time by FDG-PET scanning

Tissue Engineering - Amniotic fluid a preferred cell source for tissue-engineered diaphragmatic reconstruction

Tissue Engineering - Bone regeneration enhanced by cultured periosteal cells

Tissue Engineering - Chondrogenesis occurs in a diminished capacity in mesenchymal SC-laden hydrogels

Tissue Engineering - Limbal epithelia cultured on fibrin gels grafted for ocular surface reconstruction

Tissue Engineering - New data illuminates research in tissue engineering

Tissue Engineering - Reports add new data to tissue engineering research

Tissue Engineering - Tissue-engineered cartilage chondrocytes can be immortalized

Tobacco Use - An Internet-based anti-smoking intervention proved efficacious at 90 days

Tobacco Use - Internet websites are a new vehicle for smoking cessation

Tobacco Use - Recent studies add new data to tobacco use research

Tongue Cancer - Poor prognosis of tongue carcinoma associated with expression of Bcl-2

Transforming Growth Factor - Transforming growth factor-beta signaling pathways are altered in human cancer

Transitional Cell Carcinoma - Transitional cell carcinoma treated by gemcitabine and paclitaxel second-line chemotherapy

Transplant Medicine - After bone marrow transplant, weight loss appears to contribute to increased mortality

Transplant Medicine - After cardiac transplant, early stage graft vasculopathy is accompanied by hypersensitivity

Transplant Medicine - Findings advance knowledge in transplant medicine research

Transplant Medicine - For heart transplant recipients, virtual crossmatch may improve organ availability

Transplant Medicine - Lymphoproliferative disorder is serious complicating outcome of cardiac transplantation

Transplant Medicine - Medwave's blood pressure monitoring technology studied in difficult liver transplant cases

Transplant Medicine - Novel method may allow transplant of islet cells from single donor into multiple recipients

Transplant Medicine - Orthotopic liver transplantation can precede live virus immunization

Transplant Medicine - Pre-op creatinine clearance <40 ml/min is an outcome marker after orthotopic heart transplant

Transplant Medicine - Reports describe recent advances in transplant medicine research

Transplant Medicine - Researchers' data advance transplant medicine research

Transplantation Biology - Liver transplantation can be advantageous for hepatitis C virus-positive patients

Transplantation Biology - Liver transplantation can increase survival in children with hepatocellular carcinoma

Tuberculosis - Co-author of article in The Lancet says TB drug pipeline shows major progress

Tuberculosis - MDR-TB present in Indonesia but not a major TB-control problem in Mimika district

Tuberculosis Control - Pulmonary tuberculosis may be controlled and prevented by up-regulating NK cell function

Tuberculosis Diagnosis - ELISPOT and skin test cut-offs determined for MTB diagnosis in Gambia

Tuberculosis Diagnosis - Tuberculosis diagnosis delay due to lack of patient education and health worker incompetence

Tuberculosis Drug Resistance - Multidrug-resistant tuberculosis and rifampin resistance prevalence high in Bujumbura

Tuberculosis Drug Resistance - Multidrug-resistant tuberculosis risk factors in Europe determined

Tuberculosis Epidemiology - Multidrug-resistant tuberculosis prevalence is high in Ho Chi Minh City

Tuberculosis Epidemiology - Severe infectious tuberculosis in childhood may become epidemiologically important

Tuberculosis Epidemiology - Tuberculosis prevalence and infection rates higher in prisoners than in general population

Tuberculosis Genetics - Tuberculosis resistance associated with IFN-gamma gene polymorphisms

Tuberculosis Healthcare - Tuberculosis care access and quality improved by government-NGO collaboration

Tuberculosis Pathogenesis - P40 overexpression in lungs related to slightly impaired resistance during tuberculosis

Tuberculosis Risk Factors - Interferon-gamma gene polymorphisms associated with microscopy-positive tuberculosis

Tuberculosis Screening - Village outreach improves speed but not extent of case finding in smear-positive TB

Tuberculosis Therapy - Fluoroquinolones active against drug-resistant tuberculosis

Tuberculosis Therapy - Tuberculosis therapy compliance improved by directly observed treatment

Tuberculosis Vaccine - Oral tuberculosis vaccine produced from a transgenic plant is immunogenic

Tumor Lysis Syndrome - Hyperuricemia corrected with reduced-dose rasburicase

Type 1 Diabetes - Self-management-based patient education program for hypoglycemia therapy in diabetes is adequate

Type 1 Diabetes - Serum CXCL10 level may be used to assess pathophysiology of type 1 diabetes disease course

Type 2 Diabetes - CytRx's RNAi screening technology supported by publication of scientific article, says company

Type 2 Diabetes - Dopamine D3-RA had a positive effect on renal morphology and albuminuria in type 2 diabetes

Type 2 Diabetes - Gly482Ser variant in PPARGC1 plays a role in type 2 diabetes risk

Type 2 Diabetes - Hypertriglyceridemia, waist-hip ratio, and family T2DM history increase diabetes risk

Type 2 Diabetes - Metformin and TZDs improved fasting hepatic insulin sensitivity and glucose clearance

Type 2 Diabetes - Neuroanatomical framework for the role of the brain in type 2 diabetes was determined

Type 2 Diabetes - Postprandial deterioration of endothelial dysfunction in diabetes is decreased by vitamin C

Vaccinia Vaccine - Immune recognition by natural killer cells depends on cytotoxicity receptors

Vaccinia Virus - Vaccinia virus proteins have been identified in intracellular mature virion particles

Vancomycin-Resistant Enterococcus - Epidemic VRE nosocomial spread controlled by strict infection control measures

Vascular Disease - Cleveland Clinic reports research results of aspirin alone, in combination with clopidogrel

Vector Development - Findings in vector development provide new insights

Vector Development - Recent findings in vector development provide new insights

Virology - Antibodies that ligate CD40 and OX40 have different effects

Virology - Immunocontraceptive effects are produced by a recombinant myxoma virus

Virology - Infectious bronchitis virus protein displays differences in localization and turnover

Virology - Metapneumovirus surface glycoproteins function in protective immunity

Virology - Researchers report details of new studies and findings in the area of virology

West Nile Virus - West Nile virus virulence in mice is attenuated by a single amino acid substitution

Wilms Tumor - Value of surgery in directing therapy for patients with Wilms tumor assessed

Wound Care - Ohio hospital's wound care center to offer hyperbaric oxygen therapy

Yellow Fever Vaccine - Recombinant yellow fever 17D vaccine expresses Lassa virus glycoproteins

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