Published in Health and Medicine Week, April 20th, 2006
Study 1: The small molecule inhibitor PS1145 targets activity in prostate cancer cells.
According to recent research from the United States, "a key antiapoptotic transcription factor, nuclear factor kappa-B (NF-kappaB), is known to be critically important for tumor cell growth, angiogenesis and development of metastatic lesions. We and others showed previously that NF-kappaB transcription factor was constitutively activated in androgen-independent prostate carcinoma (PC) cell lines due to the upregulated activity of inhibitor of NF-kappaB kinases (IKK)."
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