Cytomegalovirus Vaccine
Cytomegalovirus vaccine induces T cell responses in seronegative recipients
Published in Health and Medicine Week, April 20th, 2006
"Towne CMV vaccine is safe and immunogenic, though its protective efficacy has yet to be optimized. We describe antigen-specific T cell responses to Towne vaccination," wrote M.A. Jacobson and colleagues of the University of California, San Francisco.
"Three thousand pfu Towne CMV vaccine were given to 12 CMV-seronegative volunteers. CMV-specific CD4+ and CD8+ T cell proliferation and IFN gamma expression were measured by flow cytometry after stimulation...
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