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Gliomas

Glioma response to radiotherapy predicted by early temporal changes

Published in Health and Medicine Week, April 27th, 2006

Glioma response to radiotherapy (RT) could be predicted by early temporal changes.

In a recent article published in the International Journal of Radiation Oncology Biology Physics, scientists in the United States conducted a study "to determine whether cerebral blood volume (CBV) and cerebral blood flow can predict the response of high-grade gliomas to RT by taking into account spatial heterogeneity and temporal changes in perfusion. Twenty-three patients with high-grade gliomas underwent conformal RT, with magnetic resonance imaging perfusion before and at Weeks 1-2 and 3-4 during RT. Tumor perfusion was classified as high, medium, or low."

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