Depression
Atypical antipsychotics may augment the therapeutic efficacy of SSRIs
Published in Health and Medicine Week, May 18th, 2006
According to a study from the United States, "APDs, e.g. olanzapine and risperidone, have been reported to be effective adjunctive treatment for depression if selective serotonin (5-HT) reuptake inhibitors (SSRIs) alone are ineffective. We utilized microdialysis in awake, freely moving rats to study the effect of risperidone in combination with citalopram, an SSRI, on extracellular 5-HT, dopamine (DA), and norepinephrine (NE) efflux in rat medial prefrontal cortex (mPFC)."
M. Huang and...
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