Glioma
Glioma patients experienced cellular immune defects
Published in Health and Medicine Week, May 18th, 2006
According to a study from the United States, "Immunosuppression is frequently associated with malignancy and is particularly severe in patients with malignant glioma. Anergy and counterproductive shifts toward T(H)2 cytokine production are long-recognized T-cell defects in these patients whose etiology has remained elusive for >30 years."
"We show here that absolute counts of both CD4+ T cells and CD4+CD25+FOXP3+CD45RO+ T cells (T-regs) are greatly diminished in patients with malignant glioma, but T-regs frequently represent an increased fraction of the remaining CD4 compartment," explained...
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