Urology
Hepatocyte growth factor protects from kidney cell-crystal interaction
Published in Health and Medicine Week, June 22nd, 2006
N. Tei and colleagues, Osaka University, wrote that the study was done "to investigate whether HGF has a protective role against crystal-cell interaction and crystal deposits in a stone-forming rat model kidney."
"Crystal-cell interaction is an important step during the early stages of stone formation. High oxalate levels induce cell injuries and increase adhesion of calcium oxalate monohydrate (COM) crystals to renal tubular cells. HGF was initially identified as the most potent growth factor for hepatocytes...
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