Tobacco Use
Cigarette smoke reprograms hypothalamic neuropeptide Y-axis to promote weight loss
Published in Health and Medicine Week, July 31st, 2006
"Despite irrefutable epidemiologic evidence, cigarette smoking remains the major preventable cause of lung disease morbidity worldwide. The appetite-suppressing effect of tobacco is a major behavioral determinant of smoking, but the underlying molecular and neuronal mechanisms are not understood," investigators in Australia report.
H. Chen and colleagues at the University New South Wales explained, "Neuropeptide Y (NPY) is an orexigenic neuropeptide, whose activity in the hypothalamic paraventricular nucleus governs appetite. To compare the effects of...
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