Published in Health and Medicine Week, August 7th, 2006
"Hypoxia inducible factor (HIF), a master regulator of critical genes for cell survival under hypoxic conditions, is known to be related to tumorigenesis and progression of renal cell carcinoma. N-methylpyrrole (Py)-N-methylimidazole (Im) hairpin polyamides are synthetic organic compounds that recognize and bind to the minor grooves of specific DNA sequences," investigators in Japan report.
"We synthesized three Py-Im hairpin polyamides targeting the flanking...
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