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Antibacterial Agents

ALT plus systemic antibiotics are effective for IV catheter-related bacteremia

Published in Health and Medicine Week, August 7th, 2006

Antibiotic-lock therapy (ALT) combined with systemic antibiotics seems to be effective for treating catheter-related bacteremia (CRB), especially in Gram-negative and coagulase-negative staphylococci episodes.

"Infection is one of the main problems associated with long-term central venous catheters. This study assesses the effectiveness of ALT for treating CRB," scientists writing in the Journal of Antimicrobial Chemotherapy report.

"CRB was defined as quantitative blood culture counts through any catheter lumen 5-fold greater than concurrent peripheral blood culture, and qualitative blood culture positive for the same microorganism in all...

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