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Mangiferin reduces oxidative damage and activates mitochondrial energy metabolism

Published in Health and Medicine Week, August 14th, 2006

Study findings suggest that the protective effect of mangiferin can be attributed to its reducing effect on oxidative damage and activation of mitochondrial energy metabolism in an experimentally-induced myocardial infarcted rat model.

According to recent research from India, "Mangiferin, from the leaves of Mangifera indica Linn., has been suggested as useful in the treatment of cardiovascular disorders. In the present study this drug was examined on the alteration of cardiac energy metabolism in isoproterenol (ISPH) administered myocardial infarcted rats."

"ISPH (20 mg/kg b.w.), which was administered s.c. twice at an interval of 24 h, caused...

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