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Cancer Gene Therapy

Ovarian cancer apoptosis enhanced by ionizing radiation adenoviral vector

Published in Health and Medicine Week, September 4th, 2006

According to a study from the United States, ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.

"Ovarian cancer is the fifth most common cause of cancer-related death in women. Current interventional approaches, including debulking surgery, chemotherapy, and/or radiation have proven minimally effective in preventing the recurrence and/or mortality associated with this malignancy," wrote L. Emdad and colleagues, Columbia University.

"Subtraction hybridization applied to terminally differentiating human melanoma cells identified melanoma differentiation associated gene-7/interleukin-24...

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