Neuroscience
A neuroprotectant inhibits mitochondrial membrane depolarization
Published in Health and Medicine Week, October 2nd, 2006
"We have previously reported that a neuroprotective substance, serofendic acid, was purified and isolated from fetal calf serum. Here, we investigated the effect of serofendic acid on glutamate-induced apoptosis using rat primary cultures of cortical neurons," wrote T. Kume and colleagues, Kyoto University.
"Exposure of the cortical cultures to relatively low concentration of glutamate (100 mcM) induced neuronal death and nuclear fragmentation....
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