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Vitamin B12 reduces ribavirin-induced genotoxicity in lymphocytes

Published in Health and Medicine Week, October 2nd, 2006

Vitamin B12 reduces ribavirin-induced genotoxicity in phytohemaglutinin-stimulated human lymphocytes.

According to a study from Serbia, "Ribavirin, an N-glycosyl nucleoside (1,6-D-ribofuranosyl-1,2,4-triazole-3 carboxamide), is a synthetic purine nucleoside analogue with a broad spectrum of antiviral activity, however, its high toxicity poses a major disadvantage of its use as a therapeutic. Various studies have shown that vitamin B12 plays a significant role in maintaining the stability of the human genome."

"We therefore investigated the potential beneficial effect of vitamin B12 in reducing ribavirin-induced...

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