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Experimental Biology

Study data from Nihon University, Department of Anatomy update understanding of experimental biology

Published in Health and Medicine Week, January 22nd, 2007

Data detailed in "Inflammatory biomarker, neopterin, suppresses B lymphopoiesis for possible facilitation of granulocyte responses, which is severely altered in age-related stromal-cell-impaired mice, SCI/SAM" have been presented. According to a study from Tokyo, Japan, "Neopterin is produced by monocytes and is a useful biomarker of inflammatory activation. We found that neopterin enhanced in vivo and in vitro granulopoiesis triggered by the stromal-cell production of cytokines in mice."

"The effects of neopterin on B lymphopoiesis during the enhancement of granulopoiesis were determined using the mouse model of senescent stromal-cell impairment (SCI), a subline of...

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