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Vascular Disease
Contribution of cholesterol transporter to vascular disease
November 5th, 2007
Low-density lipoprotein (LDL), a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a report published online in EMBO reports. The study reveals a link between native LDL (nLDL) and the vascular endothelial growth factor receptor 1 (VEGFR1), which plays a central role in blood vessel formation. LDL is responsible for transporting cholesterol from the liver to peripheral tissues. During transit in the blood, cholesterol can be deposited causing the formation of plaques that lead to hardening of the arteries. Vascular diseases such as thrombosis, stroke and heart attacks are associated with this...
Source: Health & Medicine Week (2007-11-05)
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