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Breast Cancer
Humboldt University publishes research in breast cancer
November 5th, 2007
According to recent research from Berlin, Germany, "HER2 is an important tumour marker in breast cancer. However, there is controversy regarding which method reliably measures HER2 status." "This study evaluates the concordance between HER2 gene amplification in invasive breast cancer determined by fluorescence in. situ hybridisation (FISH) and a new silver enhanced in situ hybridisation (SISH) technique. Ninety-nine cases were analysed by direct-labelled manual FISH (PathVysion (R), Abbott/Vysis) and bright field automated SISH (INFORM (R), Ventana). For comparison, all specimens were stained by immunohistochemistry (Dako-HercepTest (TM) and Ventana-PATHWAY (R) 4B5)....
Source: Health & Medicine Week (2007-11-05)
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