Sezary Syndrome
Reports outline Sezary syndrome study findings from University Medical Center
Published in Health and Medicine Week, December 13th, 2010
2010 DEC 13 -- "Dysfunctions in memory T cells contribute to various inflammatory autoimmune diseases and neoplasms. We hypothesize that investigating the differences of genetic profiles between resting and activated naive and memory T cells may provide insight into the characterization of abnormal memory T cells in diseases, such as Sezary syndrome (SS), a neoplasm composed of CD4(+) CD45RO(+) cells," researchers in the United States report.
"We determined genes distinctively expressed between resting and activated naive and memory cells. Levels of up-regulated genes in resting and activated memory cells were measured in SS PBMCs, which were largely...
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