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Peptides and Proteins

Russian Academy of Sciences, Sechenov Institute of Evolutionary Physiology and Biochemistry reports research in peptides and proteins

Published in Health and Medicine Week, December 13th, 2010

2010 DEC 13 -- Fresh data on peptides and proteins are presented in the report 'Changes in the activity of amyloid-degrading metallopeptidases leads to disruption of memory in rats.' "In old male Wistar rats (older than 12 months), or adult males (3-4 months) subjected to prenatal hypoxia (7% O2, 3 h, E14), a disruption of short-term memory was observed. Prenatal hypoxia also led to a decrease in the brain cortex of the levels of expression of the metallopeptidases neprilysin (NEP) and endothelinconverting enzyme (ECE-1) which regulate some neuropeptides and are the main amyloid-beta ('ß)-degrading enzymes," researchers in Russia report.

"Moreover we...

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