Microbodies
New microbodies findings from Northwestern University, Department of Pathology published
Published in Health and Medicine Week, January 3rd, 2011
2011 JAN 3 -- Researchers detail in 'Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression,' new data in microbodies. "PBP (peroxisome-proliferator-activated receptor-binding protein) [Med1 (mediator 1)/TRAP220 (thyroid-hormone-receptor-associated protein 220)] is essential for mammary gland development. We established a mammary epithelial cell line with a genotype of PBPLoxP/LoxP by expressing an active form of Notch4," investigators in the United States report.
"Null mutation of PBP caused severe growth inhibition of the...
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