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Cell Science

New cell science study results from University of Iowa described

Published in Health and Medicine Week, January 3rd, 2011

2011 JAN 3 -- "Using a newly developed microfluidic chamber, we have demonstrated in vitro that Ca2+ functions as a chemoattractant of aggregation-competent Dictyostelium discoideum amoebae, that parallel spatial gradients of cAMP and Ca2+ are more effective than either alone, and that cAMP functions as a stronger chemoattractant than Ca2+," scientists writing in the Journal of Cell Science report.

"Effective Ca2+ gradients are extremely steep compared with effective cAMP gradients. This presents a paradox because there is no indication to date that steep Ca2+ gradients are generated in aggregation territories," wrote A. Scherer and colleagues,...

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