Biochemistry
Research on Biochemistry Published by Scientists at University of Innsbruck
Published in Health and Medicine Week, March 28th, 2011
2011 MAR 28 -- A new study, 'p65 controls NF-'B activity by regulating cellular localization of I'Bß,' is now available. According to a study from Innsbruck, Austria, "NF-'B (nuclear factor 'B) controls diverse cellular processes and is frequently misregulated in chronic immune diseases or cancer. The activity of NF-'B is regulated by I'B (inhibitory 'B) proteins which control nuclear-cytoplasmic shuttling and DNA binding of NF-'B."
"In the present paper, we describe a novel role for p65 as a critical regulator of the cellular localization and functions of NF-'B and its inhibitor I'Bß. In genetically modified p65-/-cells, the localization of...
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