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Developmental Biology

Research from Max Planck Institute for Molecular Cell Biology and Genetics Provides New Data on Developmental Biology

Published in Health and Medicine Week, September 5th, 2011

2011 SEP 5 -- New research, "Survival strategies of a sterol auxotroph," is the subject of a report. "The high sterol concentration in eukaryotic cell membranes is thought to influence membrane properties such as permeability, fluidity and microdomain formation. Drosophila cannot synthesize sterols, but do require them for development," scientists in Dresden, Germany report.

"Does this simply reflect a requirement for sterols in steroid hormone biosynthesis, or is bulk membrane sterol also essential in Drosophila' If the latter is true, how do they survive fluctuations in sterol availability and maintain membrane homeostasis' Here, we show that Drosophila...

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