Atherosclerosis
Scientists at Southwest University Publish New Data on Atherosclerosis
Published in Health and Medicine Week, November 14th, 2011
2011 NOV 14 -- In this recent report, researchers in Chongqing, People's Republic of China conducted a study "To investigate the effects of darapladib, a specific inhibitor of lipoprotein-associated phospholipase A2 (lp-PLA2), on inflammation and atherosclerotic formation in the low density lipoprotein receptor (LDLR)-deficient mice. Six-week-old LDLR-deficient mice were fed an atherogenic high-fat diet for 17 weeks and then randomly divided into two groups."
"One group was administered darapladib (50 mg.kg(-1).d(-1); po) for 6 weeks. The other group was administered saline as a control. Serum lipid levels were measured using the corresponding kits, and...
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