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Wellcome Trust Sanger Institute, Cambridge

Cell-cell & cell-extracellular matrix contacts essential for NSC maintenance

Published in Healthcare Finance, Tax and Law Weekly, March 9th, 2005

Cell-cell and cell-extracellular matrix contacts may be essential for neural stem cell maintenance.

According to a recent review in the Journal of Neuroscience Research, "Neural stem cells (NSC) are a tissue-specific subtype of self-renewing and multipotent cells that can give rise to all neural populations.

"In this review, the importance of maintaining cell-cell contacts in the study of NSC is highlighted, and data obtained from some crucial single-cell studies is compared to results obtained from neurospheres, where aggregates of NSC are grown in suspension."

"In particular," said L.S. Campos and colleagues, "results...

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