Georgia State University, Atlanta
Sulfonated naphthyl porphyrins active against HIV-1
Published in Healthcare Finance, Tax and Law Weekly, May 11th, 2005
"Sulfonated 5,10,15,20-tetra(1-naphthyl)porphyrin (T1NapS) and 5,10,15,20-tetra(2-naphthyl)porphyrin (T2NapS) and their copper and iron chelates show activity against the human immunodeficiency virus (HIV-1).
"The porphyrins were prepared by sulfonation of the parent structures with sulfuric acid. More highly sulfonated structures were prepared by sulfonation for longer times," researchers in the United States report.
"Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry showed species with as many as eight sulfonates.
"Some of the mass...
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