Kitasato University, Kanagawa

Testicular androgen receptors analyzed, expression defined

Published in Healthcare Finance, Tax and Law Weekly, June 15th, 2005

Recent research published from Japan has elucidated the expression of steroid receptor coactivator-1 (SRC-1) and p300/CBP/co-integrator protein (p/CIP) in the mouse testis.

"The function of the testis is regulated by androgens. The activity of testicular androgens is expressed through androgen receptors and many kinds of coactivators in a similar way as with other steroid hormones.

"In this study," wrote K. Fujita and colleagues, Kitasato University, "the expression of androgen receptors (AR) SRC-1 and p/CIP in the mouse testis was analyzed by immunohistochemistry."

"The AR signals were detected in the nucleus of peritubular...

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Source: Healthcare Finance, Tax and Law Weekly (2005-06-15)

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