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Healthcare Finance, Tax and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . September 28th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Healthcare Finance, Tax and Law Weekly | Other Publications

A&G Pharmaceutical - Theranostics company completes series A financing

AMDL, Inc. - Oncology test maker closes second private offering

Align Technology - California county court overrules challenges to teeth straightening technology

Allergan - Eric Brandt resigns to accept position as president of Avanir Pharmaceuticals

Amnis Corp. - Life science instrument maker closes $3M series C financing round

Amylin Pharmaceuticals - Metabolic disorders drug developer announces public offering of common stock

Apotex Corp. - Court rules in favor of Canadian drug maker in gabapentin ruling

Array BioPharma - Small-molecule drug maker announces lease restatement

Arriva Pharmaceuticals - Anti-inflammatory therapy developer names new general counsel

Arrow International - Disposable catheter maker revises fourth quarter, full year sales estimates

Avitar - Avitar, Inc. announces AMEX delisting

Biofrontera AG - German pharmaceutical firm places convertible bond

Biolex Therapeutics - Protein therapeutics company raises $36M in venture financing

Biophan Technologies - Three new patents issued relating to MRI safety and visualization

Boston Life Sciences - Neuroscience company announces $12.7M private placement

Alfacell Corp. - Update provided on Onconase malignant mesothelioma phase IIIb trial

Applied Biotechnology Institute - Plant-based vaccines for animal health reviewed

Aristotle University of Thessaloniki - Screening progeny of CHD can identify children at excessive risk

Atrium Medical Center, Heerlen - Combination of tiotropium and formoterol effective to treat COPD

Avos Life Sciences - Reports identify shift in strategic performance of top pharma companies

Baylor College of Medicine, Houston - Coadministration of raloxifene and simvastatin tested to reduce plasma lipids

Besler Consulting - Revenue management company provides staffing to Westchester County Health Care

Biogen Idec - Supplemental BLA submitted to U.S. FDA for Rituxan

BlueCross BlueShield of South Carolina - South Carolina insurance company to offer discounted cosmetic dentistry program

Brigham & Women's Hospital, Boston - Managed ventricular pacing mode improves safety

Cadence Pharmaceuticals - Phase III trial of CPI-226 initiated for catheter-related infections

Cardiac Science - U.S. CDC purchases automatic public-access defibrillators

Celera Diagnostics - Celera Diagnostics identifies markers linked to increased risk of heart attack

Cephalon - German agency gives go-ahead to market modafinil for shift-work sleep disorder

Children's Hospital of Philadelphia - Implantation technique may decrease risk of stent malposition

Children's Hospital, Boston - Hand sanitizer gel reduces spread of GI infections

Children's Hospital, Boston - Study finds potentially better test for infant iron deficiency

City of Hope National Medical Center, Durarte - Portal vein-delivered adjuvant floxuridine has low hepatotoxicity

Cyberonics - Data from D-02 study treated with vagus nerve stimulation published in journal

Cyto Pulse Sciences - Company works with USAMRIID on Marburg vaccine delivery development

Denver VA Medical Center - Cerebellar neuron apoptosis studied, mechanism of apoptotic cascade defined

Deutsch Herzzentrum, Berlin - Researchers describe findings in stents studies

Dionex Chemical Corp. - Trace concentrations of bromate found in municipal and bottled drinking waters

Drexel Univ. College of Medicine, Philadelphia - Cholesterol crystals analyzed, gallbladder Na+/H+ activity clarified

Epocrates - Medical information company announces alliance with school of dentistry

European Society of Cardiology - Study shows new anti-thrombotic therapy effective, safer for ACS patients

Finance - Predictive medicines company announces private placement financing

Fischer International - Hospice services company selects identity software for compliance, audit needs

Geron - Studies demonstrate engraftment of hESC-derived cardiomyocytes in rodent heart

Harvard Health Publications - Publication examines bypass surgery versus off-pump bypass

Harvard Medical School - Oocytes generated in adult ovaries by putative germ cells in bone marrow

Harvard University - Cortical progenitors studied, spindles and asymmetric cells clarified

Harvard University - Dopamine signaling and depression analyzed, link revealed

Healthcare Costs - Blue Cross and Blue Shield of New Mexico educate Medicare beneficiaries

Herlev University Hospital - Simultaneous scintigraphy can reveal CV information in hyperparathyroid patients

Hiroshima University - MSC and hydroxyapatite ceramic transplant treats severe osteochondral damage

Hokkaido University - Permeability of adhesive resin films studied

Hospital for Sick Children, Toronto -  Escherichia coli ProP studied, role of intermolecular coiled coil revealed

INSERM U499, Lyon - Atheroma cholesterol metabolism analyzed, storage and repression clarified

INSERM, U620, Rennes - 34+ HSCs are targets for carcinogenic polycyclic aromatic hydrocarbons

IRCCS, Rome - Analysis of gliosarcomas intimated the existence of two subtypes

Illinois Medical District - NanoInk and GenUs BioSystems graduate from Chicago Technology Park

Inovio Biomedical Corp. - Melanoma treatment discussed at oncology meeting

Institute Pasteur, Paris - Interleukin-2 (IL-2) responsiveness of CD4 and CD8 lymphocytes chronicled

InterGenetics - Company builds DNA analysis and genotyping laboratory

InterMune - Two composition of matter patents issued for Actimmune

Intercell AG - Marketing and distribution agreement signed for Japanese encephalitis vaccine

Introgen Therapeutics - Bystander effect of INGN 241 increases cancer-killing activity in breast cancer

Johns Hopkins Medical Institutions - Embryonic stem cells accrue genetic changes

Johns Hopkins University - DNA shows promise for cancer immunotherapy

Joslin Diabetes Center - Joslin Diabetes Center offers back-to-school tips for parents

Kagawa University - Growth inhibitory effect of D-allose on human ovarian carcinoma cells studied

Karolinska University Hospital - Molecular mechanisms of glucocorticoid activity clarified

Kochi Medical School - BNP level correlated with Tei index in hypertrophic cardiomyopathy

Kokura Memorial Hospital, Fukuoka - ATHEROMA study indicates that pravastatin improves hyperlipidemia

Kyoto Prefectural University of Medicine - Reports add new data to oncology research

Leiden University Medical Center - Antigens that discriminate between TB and non-TB sera have been identified

Ligand Pharmaceuticals - Pharmaceutical company requests filing extension from Nasdaq, awaits response

Lilly Research Laboratories - Inhibition of GARFT results in inhibition of macrophage cytokine secretion

Loma Linda University - Mouse ESC used for quality control testing in assisted reproductive technology

M.D. Anderson Cancer Center - Vascular endothelial growth factor receptor-1 promotes cancer invasion

Mayo Clinic - Wireless capsule endoscopy safe in patients with implantable defibrillators

Medical University of Schleswig Holstein, Lubeck - Mechanisms in alcohol-associated carcinogenesis discussed

Medicare - CMS extends Medicare project for two additional years

Memorial Sloan-Kettering Cancer Center - Alternative to abdominoperineal resection proposed

Metabolic Pharmaceuticals Limited - Pharma company names chief financial officer

Microvision, Inc. - Light scanning technology company completes $1.5 million private placement

Nagoya University - High-level expression of Fv-Fc fusion protein in egg white achieved

Nanjing University - Endotoxemia studied, inhibitory hydroxyethyl starch effects defined

National Institute of Cardiology, Mexico City - ECG is used to assess coronary reserve in patients with arteritis

National Safety Council - As America ages, falls become bigger problem

National Yang Ming University, Taipei - GST genotypes associated with oral squamous cell carcinoma

Nippon Veterinary & Animal Science University - Oligomeganephronic disease modeled, hyperfiltration and hypertrophy clarified

Nonlinear Dynamics Ltd. - Bioinformatics solutions provider provides product release update

Novartis - Femara granted FDA priority review for new indication: early breast cancer

Ohio State University - Acute-leukemia sign may signal need for different therapy

Okayama University - Irinotecan and amrubicin treated patients with non-small-cell lung cancer

Origen Therapeutics - First production of human monoclonal antibodies in chicken eggs published

Osaka University - Efficacy of contrast-enhanced power Doppler sonography assessed

PacifiCare Health Systems Inc. - Health system launches public information campaign for Medicare Part D

Par Pharmaceutical Companies, Inc. - FDA approves NDA for cholestyramine for oral suspension

PhotoMedex, Inc. - Patents for copper peptide compounds in dermatological skin disorders awarded

Quinton Cardiology Systems - Cardiology products company and Cardiac Science announce completion of merger

Royal Brompton Hospital, London - Stress ECG uniquely identifies high risk in ischemic cardiomyopathy

Royal College of Surgeons in Ireland, Dublin - T lymphocytes examined, stimulus-induced kinase phosphorylation described

Royal Victoria Hospital, Montreal - Receptor signaling studied, roles of reactive oxygen species defined

San Francisco General Hospital - PPT or standard tubes processed within 4 hours yield equivalent HIV RNA in bDNA

Sectra - Company provides PACS for breast imaging to BreastScreen New South Wales

Shanghai Medical College of Fudan University - Anti-dsDNA autoantibodies have anti-tumor effects in cancer patients

Showa University, Tokyo - Er,Cr:YSGG laser ablation evaluated in rabbit model

Soroka University, Beer-Sheva - Treatment bias examined for men and women with coronary artery disease

Sotiria Hospital, Athens - Cisplatin-combined schedules used as second-line chemotherapy in NSCLC patients

St. George's Hospital Medical School, London - Proopiomelanocortin variants linked to leptin and body fat in women

St. James's University Hospital, West Yorkshire - Left hepatic trisectionectomy performed for hepatobiliary malignancy

St. Josefs Hospita, Cloppenburg - Diagnosis of impaired glucose tolerance in hypertension examined

St. Jude Children's Research Hospital - Research hospital to lead trial to investigate sickle cell anemia and stroke

Tanta University - Hepatitis B virus may be a hit and run mutagen

TargeGen, Inc. - Biopharmaceutical company closes $30 million preferred venture financing round

Teaching Hospital of the Univ. of Mainz, Wiesbaden - Local endoscopic therapy treated early-stage small-bowel adenocarcinoma

Technical Research Centre of Finland - Remarkable enhancement of drug productivity via new real-time quality control

Technical University of Berlin - Mutational biosynthesis important tool for synthesis of natural products

Technical University of Denmark - Novel software tool facilitates microarray probe design

Temple University, Philadelphia - Factor XIa examined, role of dimer in factor IX activation defined

The Perrigo Company - Tentative FDA approval granted to market Glimepiride Tablets

Tokyo Medical University - Effect of replacement therapy with hydrocortisone or levothyroxine studied

Tripos, Inc. - Drug discovery, informatics software maker partners with French company Servier

U.S. Army Med. Research Inst. of Infectious Dis. - Humoral and CD8+ responses needed to protect against Ebola infection

U.S. Centers for Disease Control & Prevention - Neonatal sepsis associated with bacterial contamination of intravenous fluids

U.S. Centers for Disease Control & Prevention - Risks identified for occupationally acquired histoplasmosis outbreaks

U.S. Food & Drug Administration - U.S. regulatory perspective on multicenter trials presented

U.S. National Institutes of Health - Gene profiling of immune responses against tumors reveals complexity

U.S. National Institutes of Health - Minority participation in cancer clinical trials increased

U.S. National Institutes of Health - Real-time MRI-guided stenting achieved in porcine model

University Hospital, Mannheim - VF patients show enhanced coagulation after in vitro LPS challenge

University Magna Graecia, Catanzaro - L-arginine and ADMA are inversely related to endothelial function in HT

University of Antwerp Hospital - Staging systems for malignant pleural mesothelioma examined

University of Athens - Free/Total PSA kinetics in patients undergoing radical prostatectomy studied

University of Birmingham - New approach to adoptive transfer shows potential in T cell therapy

University of California, Irvine - Dermatological indications and side effects of thalidomide reported

University of California, Los Angeles - Patients with cervical spine injury may harbor additional spinal damage

University of California, Sacramento - Nomogram-based IOL power adjustment effective for post-LASIK/PRK eyes

University of California, Santa Cruz - New findings in the area of neurology described

University of Cambridge - Salicylate synthase from Yersinia enterocolitica characterized

University of Groningen - Radiation damage to heart enhanced early radiation-induced lung function loss

University of Heidelberg - HIV Nef establishes superinfection immunity by downregulating CCR5 and CD4

University of Ioannina - Primary hyperlipidemia examined, association of clinical indicators clarified

University of Louvain - Researchers report details of new studies and findings in the area of hormones

University of Medicine & Dentistry of New Jersey - Loss-of-function of Nkx3.1 increased oxidative damage in prostate carcinogenesis

University of Nebraska Medical Center - Independent nursing actions in cooperative care discussed

University of New South Wales - New research shows the elderly aren't rude, just uninhibited

University of Nottingham - Concurrent SSRI and NSAID use doesn't raise risk of upper GI bleeding

University of Pennsylvania - Zygotic gene activation in the preimplantation mouse embryo studied

University of Rochester - New findings in DPT vaccines described

University of S. Florida, Tampa - Researchers provide details of new studies and findings in the area of drug development

University of Sydney - Glycemic index affects insulin-like growth factor-binding protein

University of Texas - Differences evaluated in race and gender for C-reactive protein levels

University of Texas SW Medical Center, Dallas - Metronomic chemotherapy delays prostate tumor growth in rodents

University of Tokyo - Exogenous expression of hRFI induced multidrug resistance

University of Toronto - Immune signaling molecule 4-1BB associated with type 1 diabetes

University of Ulm - Survival benefit in resectable colon cancer increased by adjuvant treatment

Vanung University, Taipei - Dehydroepiandrosterone after exercise decreases serum lipids

Vital Living, Inc. - Nutraceuticals company implements quality assurance program

Washington University, St. Louis - Researchers' findings advance colorectal cancer research

Weider Nutrition International - Vitamins, nutrition products company reports fiscal year 2005 and Q4 results

Wright Medical Group - Advanced metal for hip replacement systems with greater motion introduced

Yamagata University - Heart-type fatty acid binding protein and BNP can aid HF risk analysis

Yonsei University, Seoul - CpG ODN have limited effect in preventing type 1 diabetes

Yonsei University, Seoul - Outcomes of hand-sewn coloanal anastomosis for distal rectal cancer detailed

etrials Worldwide - Agreement to merge clinical trial software company, CEA Acquisition announced

iSurg. Corp. - ISurg Corp. introduces colorectal surgery care program for care providers

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