University of Manchester, U.K.
Recent advances in targeting regulators of apoptosis in cancer cells reviewed
Published in Healthcare Finance, Tax and Law Weekly, August 23rd, 2006
"Apoptosis is a fundamental cellular death process that is essential for normal tissue homeostasis, whose deregulation is associated with several human disease states, including cancer. Increased understanding of cancer biology has led to the hypothesis that although cancer cells are inherently resistant to the engagement of apoptosis due to the deregulation of molecular components of core apoptotic machinery or of survival signalling cascades, they are primed to die as a result of microenvironmental and oncogenic proapoptotic stress," researchers in England reported.
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