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Ovarian Cancer

Research from Nextcea, Inc. provides new data about ovarian cancer

Published in Healthcare Finance, Tax and Law Weekly, October 31st, 2007

Investigators publish new data in the report 'Drug safety evaluation through biomarker analysis--a toxicity study in the cynomolgus monkey using an antibody-cytotoxic conjugate against ovarian cancer.' According to a study from the United States, "'Antibody-cytotoxin conjugates are complex novel therapeutic agents whose toxicological properties are not presently well understood. The objective of this study was to identify serum biomarkers that correlate with MLN8866 (an Antibody-Cytotoxic Conjugate, mAb8866-CT) pathological events in monkeys and to predict the maximal tolerated dose (MTD) level using biomarkers."

"Cynomolgus monkeys were administered a single dose...

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