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Chromatography

Findings in chromatography reported from Johnson & Johnson

Published in Healthcare Finance, Tax and Law Weekly, December 17th, 2008

Fresh data on chromatography are presented in the report 'Improved liquid chromatography-Online radioactivity detection for metabolite profiling.' According to a study from Belgium, "If very-high-pressure liquid chromatography (VHPLC) is to replace conventional HPLC as the ultimate separation tool for metabolism studies in development, coupling it efficiently with online radioactivity detection (RAD) is needed. We describe the successful combination of VHPLC/RAD, facilitated by improvements in online radioactivity detection, as well as in column loading and peak capacity."

"The sensitivity of (14)C detection was improved by the use of a variable scintillation flow...

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