Published in Healthcare Finance, Tax and Law Weekly, February 25th, 2009
"The continued one-pot synthesis with 4 to a highly refined material like [5-C-14]-dimethylsulfanyltriazolepyridines 8 and 13 without any intermediate purification, six steps in the same pot from [C-14]KCN. Oxidation of the sulfur provided access to triazole-ethers upon reaction with alcohols," wrote P. Strom and colleagues, AstraZeneca.
The researchers concluded: "The triazole-ethers, 15, were obtained at fair to good yields and specific activities above 2 GBq/mmol."
Strom and colleagues...
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