St. Jude Children's Hospital
Gabapentin controls seizures in children receiving chemotherapy
Published in Healthcare Mergers, Acquisitions and Ventures Week, May 15th, 2004
"Hepatic clearance of chemotherapy drugs is increased by many antiepilepsy drugs. At our institution, new-onset seizures in children on chemotherapy are treated with gabapentin, a nonhepatic enzyme inducer. The charts of all children given gabapentin for seizures were reviewed," researchers in the United States report.
"At a median follow-up of 34 months, seizures were controlled in 74% of 50 children given gabapentin monotherapy as initial treatment: 91% of the leukemia group, 57% of the brain tumor group, and 75% of the other tumor...
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