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Sunesis Pharmaceuticals, Inc.

Sunesis begins clinical study of anticancer drug

Published in Healthcare Mergers, Acquisitions and Ventures Week, July 31st, 2004

Sunesis Pharmaceuticals, Inc. has initiated the first of two planned Phase I clinical studies of SNS-595, the company's anti-cancer small molecule drug.

The trial is an open-label multi-center, dose escalation study designed to examine the safety, tolerability, and pharmacokinetics of SNS-595 in order to establish optimal dosing regimens for use in Phase II clinical testing. The drug is a first-in-class cell cycle modulator that kills proliferating cancer cells by inducing apoptosis, or programmed cell death.

Patients with advanced malignancies are being enrolled at four centers in the U.S. In the first trial, SNS-595 will be administered as a single...

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