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Australian National University
Auditory brainstem neurons characterized in novel murine model
November 6th, 2004
A novel murine model has shed new light on neural activity in congenital deafness. In a recent study, physiologists in Australia "investigated changes in the neuronal excitability of the auditory brainstem in a congenitally deaf mouse (deafness dn/dn)." "Whole cell patch recordings from principal neurons of the medial nucleus of the trapezoid body (MNTB) showed strikingly enhanced excitability in the deaf mice when compared to control CBA mice at 12-14 days postnatal," R.N. Leao and coauthors at the Australian National University found. "MNTB neurons in normal CBA mice showed the phenotypic single action potential response...
Source: Healthcare Mergers, Acquisitions & Ventures Week (2004-11-06)
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