Healthcare Mergers, Acquisitions & Ventures Week
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International Agency for Cancer Research, Lyon
Genetic markers of therapeutic radiation sensitivity reviewed
November 6th, 2004
Known genetic biomarkers of therapeutic radiation sensitivity have been reviewed. "The occurrence of acute or late normal tissue reactions after therapeutic radiotherapy and cellular responses in in vitro radiosensitivity assays do not correlate well, suggesting that to date no one test system is suitable for predicting the risk or severity of such reactions," oncologists in France explained. "New insights into the underlying molecular mechanisms of this sensitivity are coming from studies that assess associations between common polymorphisms in DNA damage detection and repair genes and the development of adverse reactions to radiotherapy." "The...
Source: Healthcare Mergers, Acquisitions & Ventures Week (2004-11-06)
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