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Emory University
Neuronal transport may play a role in neuritic degeneration
November 6th, 2004
Neuronal transport may play a role in neuritic degeneration. According to a study from the United States, "The presence of amyloid plaques in the brain is one of the pathological hallmarks of Alzheimer disease (AD). We report here a comprehensive proteomic analysis of senile plaques from postmortem AD brain tissues. Senile plaques labeled with thioflavin-S were procured by laser capture microdissection, and their protein components were analyzed by liquid chromatography coupled with tandem mass spectrometry." "We identified a total of 488 proteins co-isolated with the plaques, and we found multiple phosphorylation sites on the neurofilament...
Source: Healthcare Mergers, Acquisitions & Ventures Week (2004-11-06)
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